Live rabbit eye model studies of optical coherence tomography guided pneumatic dissection using vertically inserted razor edge cannula for deep anterior lamellar keratoplasty

Yaning Wang; Justin D. Opfermann; James Kaluna; Ruizhi Zuo; Jesse Haworth; Axel Krieger; Bill G. Gensheimer; Jin U. Kang

doi:10.1117/12.3002995

13 March 2024 Live rabbit eye model studies of optical coherence tomography guided pneumatic dissection using vertically inserted razor edge cannula for deep anterior lamellar keratoplasty

Yaning Wang, Justin D. Opfermann, James Kaluna, Ruizhi Zuo, Jesse Haworth, Axel Krieger, Bill G. Gensheimer, Jin U. Kang

Author Affiliations +

Proceedings Volume PC12831, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXII; PC128310F (2024) https://doi.org/10.1117/12.3002995
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Here we proposed a designed, built, and evaluated 20G vertically inserted razor edge cannula (VIREC) robotic device guided by optical coherence tomography (OCT) for pneumatic dissection. The fiber sensor was glued inside the needle at a fixed offset of ~500 um. During the experiment, the robotic needle driver precisely moves the VIREC based on the surgeon input which is carefully monitored by the M-mode OCT system. Once the needle is inserted into the desired depth, the air is injected by the surgeon to separate stroma from Descemet’s membrane (DM). During in vivo study (N=8), the “big bubble” was effectively generated in six of eight eyes tested and DM was perforated in two eyes. This demonstrated the reliability and effectiveness of VIREC for “big bubble” DALK.

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Yaning Wang, Justin D. Opfermann, James Kaluna, Ruizhi Zuo, Jesse Haworth, Axel Krieger, Bill G. Gensheimer, and Jin U. Kang "Live rabbit eye model studies of optical coherence tomography guided pneumatic dissection using vertically inserted razor edge cannula for deep anterior lamellar keratoplasty", Proc. SPIE PC12831, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXII, PC128310F (13 March 2024); https://doi.org/10.1117/12.3002995

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KEYWORDS

Optical coherence tomography

Cornea

Eye models

Bubbles

Robotics

Surgery

Eye

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