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13 March 2024 A rotating photoacoustic and ultrasound imaging system for whole-body small animal studies
Alissa Silva, Michael D. Brown, Nam Huynh, Khoa Pham, Edward Zhang, Olumide Ogunlade, Paul Beard, Ben T. Cox
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Proceedings Volume PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024; PC128420L (2024) https://doi.org/10.1117/12.3008993
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
We present the developments on a rotating multiple-view dual-mode photoacoustic/ultrasound system for in-vivo, non-invasive, whole-body small-animal imaging and based on planar Fabry-Pérot sensor-based tomography to overcome present challenges. Single planar Fabry-Pérot sensors suffer from an incomplete view of the acoustic fields, which leads to blurring and artefacts in tissue sample images. Increasing the fields of view would relax this limitation. Another contribution to the degradation of the image quality are wavefront aberrations stemming from spatially-varying sound speeds in a tissue sample and which limit the imaging depth. These can however be corrected by carrying out ultrasound computed tomography.
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Alissa Silva, Michael D. Brown, Nam Huynh, Khoa Pham, Edward Zhang, Olumide Ogunlade, Paul Beard, and Ben T. Cox "A rotating photoacoustic and ultrasound imaging system for whole-body small animal studies", Proc. SPIE PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024, PC128420L (13 March 2024); https://doi.org/10.1117/12.3008993
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KEYWORDS
Ultrasonography
Photoacoustic spectroscopy
Acoustics
Animals
Imaging systems
Biological samples
Sensors
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