Metasurface-enhanced spectrochemical tissue diagnostics and biosensing

Filiz Yesilkoy

doi:10.1117/12.3008316

13 March 2024 Metasurface-enhanced spectrochemical tissue diagnostics and biosensing

Filiz Yesilkoy

Proceedings Volume PC12855, Advanced Chemical Microscopy for Life Science and Translational Medicine 2024; PC128550K (2024) https://doi.org/10.1117/12.3008316
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Label-free and nondestructive mid-infrared (MIR) vibrational hyperspectral imaging has gained significance as a valuable analytical tool for analyzing biomedical tissue samples. However, the complex chemical composition and heterogeneous nature of tissue specimens along with the weak interaction of infrared light with biomolecules, pose limitations on the analytical performance of traditional MIR chemical imaging. In this talk, I will introduce an advanced MIR spectrochemical tissue imaging technique that utilizes plasmonic metasurfaces to enable the capture of quantitative molecular maps of large-area murine brain tissue sections. The proposed surface-enhanced chemical imaging method using plasmonic metasurfaces has great potential for translational biomedical research and diagnostic clinical histopathology.

Conference Presentation

Citation Download Citation

Filiz Yesilkoy "Metasurface-enhanced spectrochemical tissue diagnostics and biosensing", Proc. SPIE PC12855, Advanced Chemical Microscopy for Life Science and Translational Medicine 2024, PC128550K (13 March 2024); https://doi.org/10.1117/12.3008316

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