Decay of photoacoustic signals from biological tissue irradiated by near infrared laser pulses

Grzegorz Gondek; Teng Li; Richard Lynch; Richard J. Dewhurst

doi:10.1117/1.2360690

1 September 2006 Decay of photoacoustic signals from biological tissue irradiated by near infrared laser pulses

Grzegorz Gondek, Teng Li, Richard Lynch, Richard J. Dewhurst

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Journal of Biomedical Optics, Vol. 11, Issue 5, 054036 (September 2006). https://doi.org/10.1117/1.2360690

Abstract

We describe the phenomenon of a sudden decrease in the amplitude of photoacoustic signals arising from nanosecond laser pulse irradiation of biological samples, measured in vitro. Several dental enamel and chicken/turkey breast samples are examined. Moderate optical energy densities (i.e., about 300 mJ/cm2) are used, typical of those exploited in photoacoustic investigations. Measurements show a rapid decay of photoacoustic signals within the first few laser pulses absorbed by the sample. This phenomenon indicates that laser irradiation interacts with biological samples, causing long-term physical changes that can be attributed to a reduction of optical absorption within the samples.

©(2006) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Grzegorz Gondek, Teng Li, Richard Lynch, and Richard J. Dewhurst "Decay of photoacoustic signals from biological tissue irradiated by near infrared laser pulses," Journal of Biomedical Optics 11(5), 054036 (1 September 2006). https://doi.org/10.1117/1.2360690

Published: 1 September 2006

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