Developing compact multiphoton systems using femtosecond fiber lasers

Shuo Tang; Jian Liu; Tatiana B. Krasieva; Zhongping Chen; Bruce Jason Tromberg

doi:10.1117/1.3153842

1 May 2009 We will do our best to have your figures appear in color online. Since you submitted your figures as TIFF, this shouldn't be a problem. When you receive your proof, if the PDFs are in color, then the figures will appear in color online.

Shuo Tang, Jian Liu, Tatiana B. Krasieva, Zhongping Chen, Bruce Jason Tromberg

Author Affiliations +

Journal of Biomedical Optics, Vol. 14, Issue 3, 030508 (May 2009). https://doi.org/10.1117/1.3153842

Abstract

We implement a fiber-delivered compact femtosecond fiber laser at 1030-nm wavelength in multiphoton imaging. The laser pulse duration is 150 fs, the average power is 200 mW, and the repetition rate is 40 MHz. The laser measures 200×160×45 mm in size and its output is delivered through a photonic bandgap fiber. Intrinsic second-harmonic generation signal is excited from rat tail tendon and human skin samples. Two-photon excited fluorescence signal is obtained from human skin tissues stained with exogenous fluorophore. Our results show that femtosecond fiber lasers at 1030-nm wavelength have significant potential in developing compact, all-fiber-based, portable multiphoton systems and endoscopes.

©(2009) Society of Photo-Optical Instrumentation Engineers (SPIE)

Citation Download Citation

Shuo Tang, Jian Liu, Tatiana B. Krasieva, Zhongping Chen, and Bruce Jason Tromberg "We will do our best to have your figures appear in color online. Since you submitted your figures as TIFF, this shouldn't be a problem. When you receive your proof, if the PDFs are in color, then the figures will appear in color online.," Journal of Biomedical Optics 14(3), 030508 (1 May 2009). https://doi.org/10.1117/1.3153842

Published: 1 May 2009

ACCESS THE FULL ARTICLE

JOURNAL ARTICLE
3 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

CITATIONS

Cited by 61 scholarly publications and 2 patents.

Explore citations on Lens.org

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Femtosecond fiber lasers

Fiber lasers

Second-harmonic generation

Skin

Laser development

Tissues

Femtosecond phenomena

Show All Keywords

RELATED CONTENT

Optical fiber-based photomechanical molecular delivery system
Proceedings of SPIE (February 20 2014)

High resolution multiphoton tomography of human skin in vivo and...
Proceedings of SPIE (September 08 2004)

In-vivo non-invasive multiphoton tomography of human skin
Proceedings of SPIE (October 28 2005)

Optical control of urinary bladder contraction using femtosecond-pulsed laser
Proceedings of SPIE (February 18 2011)

Noninvasive laser coagulation of the canine vas deferens, in vivo
Proceedings of SPIE (March 02 2010)

Femtosecond fiber laser system for medical applications
Proceedings of SPIE (February 24 2009)

Subscribe to Digital Library

Receive Erratum Email Alert

Show All Keywords

Keywords/Phrases

Search In:

Publication Years