Scanning laser image correlation for measurement of flow

Molly J. Rossow; William W. Mantulin; Enrico Gratton

doi:10.1117/1.3365946

1 March 2010 Scanning laser image correlation for measurement of flow

Molly J. Rossow, William W. Mantulin, Enrico Gratton

Author Affiliations +

Journal of Biomedical Optics, Vol. 15, Issue 2, 026003 (March 2010). https://doi.org/10.1117/1.3365946

Abstract

Scanning laser image correlation (SLIC) is an optical correlation technique for measuring the fluid velocity of particles suspended in a liquid. This technique combines laser scanning of an arbitrary pattern with pair cross-correlation between any two points in the pattern. SLIC overcomes many of the limitations of other optical correlation techniques for flow measurement, such as laser speckle, spatial temporal image correlation spectroscopy, and two-foci methods. One of the main advantages of SLIC is that the concept can be applied to measurements on a range of scales through simple zooming or modifications in the instrumentation. Additionally, SLIC is relatively insensitive to instrument noise through the use of correlation analysis and is insensitive to background. SLIC can provide detailed information about the direction and pattern of flow. SLIC has potential applications ranging from microfluidics to blood flow measurements.

©(2010) Society of Photo-Optical Instrumentation Engineers (SPIE)

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Molly J. Rossow, William W. Mantulin, and Enrico Gratton "Scanning laser image correlation for measurement of flow," Journal of Biomedical Optics 15(2), 026003 (1 March 2010). https://doi.org/10.1117/1.3365946

Published: 1 March 2010

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KEYWORDS

Particles

Microfluidics

Velocity measurements

Blood vessels

Blood circulation

Speckle

Microscopes

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