Resolution enhancement of confocal scanning microscopy using low-intensity imaging part of point spread function

Vannhu Le; Xiaona Wang; Cuifang Kuang; Xu Liu

doi:10.1117/1.OE.57.5.053106

10 May 2018 Resolution enhancement of confocal scanning microscopy using low-intensity imaging part of point spread function

Vannhu Le, Xiaona Wang, Cuifang Kuang, Xu Liu

Author Affiliations +

Optical Engineering, Vol. 57, Issue 5, 053106 (May 2018). https://doi.org/10.1117/1.OE.57.5.053106

Abstract

We introduce a phase mask with a left-handed azimuthal polarization to generate a special shape of point spread function. The proposed point spread function has low-intensity and small size in the central lobe. This central lobe of the point spread function is used to obtain an image on the detector, and therefore the lateral resolution is improved. The proposed method can achieve a remarkable improvement in the lateral resolution and the depth of field compared with conventional confocal scanning microscopy. The image simulation demonstrated that the images obtained by this proposed method have better imaging quality.

Citation Download Citation

Vannhu Le, Xiaona Wang, Cuifang Kuang, and Xu Liu "Resolution enhancement of confocal scanning microscopy using low-intensity imaging part of point spread function," Optical Engineering 57(5), 053106 (10 May 2018). https://doi.org/10.1117/1.OE.57.5.053106

Received: 13 January 2018; Accepted: 17 April 2018; Published: 10 May 2018

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