Combined optical and electrochemical analysis of protein binding with ITO-coated lossy-mode resonance sensor

Marcin Koba; Dariusz Burnat; Katarzyna Szot-Karpińska; Petr Sezemsky; Vitezslav Stranak; Robert Bogdanowicz; Joanna Niedziółka-Jönsson; Mateusz Śmietana

doi:10.1117/12.2540849

28 August 2019 Combined optical and electrochemical analysis of protein binding with ITO-coated lossy-mode resonance sensor

Marcin Koba, Dariusz Burnat, Katarzyna Szot-Karpińska, Petr Sezemsky, Vitezslav Stranak, Robert Bogdanowicz, Joanna Niedziółka-Jönsson, Mateusz Śmietana

Author Affiliations +

Proceedings Volume 11199, Seventh European Workshop on Optical Fibre Sensors; 111991E (2019) https://doi.org/10.1117/12.2540849
Event: Seventh European Workshop on Optical Fibre Sensors, 2019, Limassol, Cyprus

Abstract

This work discuses indium tin oxide (ITO) coated optical fiber lossy-mode resonance (LMR) sensor working in an electrochemical setup for monitoring of protein binding to the sensor’s surface. The binding mechanism has been observed simultaneously in optical and electrochemical domain. The combined measurement was enabled by the electrically conductive ITO overlay. In the experiment, biotin molecules have been used to test the collective optical and electrochemical setup and to illustrate the binding effect. It has been shown that the effect is observed in the investigated domains at applied potential, and the qualitative comparison shows high resemblance of the outcome.

Citation Download Citation

Marcin Koba, Dariusz Burnat, Katarzyna Szot-Karpińska, Petr Sezemsky, Vitezslav Stranak, Robert Bogdanowicz, Joanna Niedziółka-Jönsson, and Mateusz Śmietana "Combined optical and electrochemical analysis of protein binding with ITO-coated lossy-mode resonance sensor", Proc. SPIE 11199, Seventh European Workshop on Optical Fibre Sensors, 111991E (28 August 2019); https://doi.org/10.1117/12.2540849

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available