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5 March 2021 Laser-ablative synthesis of elemental Bi and Sm oxide nanoparticles for radiation nanomedicine
Gleb Tikhonowski, Julia C. Bulmahn, Anton A. Popov, Andrey Kuzmin, Sergey M. Klimentov, Andrei V. Kabashin, Paras N. Prasad, Elena Popova-Kuznetsova, Vladimir Duflot, Sergey M. Deyev, Irina Zavestovskaya
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Proceedings Volume 11675, Synthesis and Photonics of Nanoscale Materials XVIII; 116750H (2021) https://doi.org/10.1117/12.2586325
Event: SPIE LASE, 2021, Online Only
Abstract
Radiation nanomedicine is an emerging field, which utilizes nanoformulations of high-Z elements and nuclear agents to improve therapeutic outcome and to reduce radiation dosage. This field lacks methods for controlled fabrication of biocompatible nanoformulations. Here, we present application of femtosecond laser ablation in liquids to fabricate stable colloidal solutions of ultrapure elemental Bi and isotope-enriched samarium oxide nanoparticles (NPs). The obtained spherical Bi and Sm oxide NPs have controllable size, while Bi NPs have remarkable absorption in the near-IR region. Exempt of any toxic by-products, laser-ablated Bi and Sm oxide NPs present a novel appealing nanoplatform for nuclear and radiotherapies.
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Gleb Tikhonowski, Julia C. Bulmahn, Anton A. Popov, Andrey Kuzmin, Sergey M. Klimentov, Andrei V. Kabashin, Paras N. Prasad, Elena Popova-Kuznetsova, Vladimir Duflot, Sergey M. Deyev, and Irina Zavestovskaya "Laser-ablative synthesis of elemental Bi and Sm oxide nanoparticles for radiation nanomedicine", Proc. SPIE 11675, Synthesis and Photonics of Nanoscale Materials XVIII, 116750H (5 March 2021); https://doi.org/10.1117/12.2586325
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KEYWORDS
Nanoparticles
Bismuth
Oxides
Samarium
Nanomedicine
Femtosecond phenomena
Laser ablation
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