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20 December 2021 Spectrophotometry of native cytological smears from the cervix in cervical cancer screening
O. Peresunko, Ju. Galushko, P. Riabyi, N. Horodynska, S. Yermolenko, D. Burkovets, K. Chala
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Proceedings Volume 12126, Fifteenth International Conference on Correlation Optics; 121260P (2021) https://doi.org/10.1117/12.2615512
Event: Fifteenth International Conference on Correlation Optics, 2021, Chernivtsi, Ukraine
Abstract
The aim of this work is to improve the diagnosis of cervical cancer by introducing laser polarimetry and spectro polarization methods of investigation. We have proposed a novel approach for the differentiation of squamous cell carcinoma and cervical adenocarcinoma using laser optics. Obtained by the method of laser polarimetry by Stokes parameter S4 of native smear with adenocarcinoma of the cervix and squamous cell carcinoma, as well as scraping of the mud canal with endometrial adenocarcinoma and flat cell cancer allows to reliably differentiate the norm from cancer in the native smear and adenocarcinoma from the flat cell cancer in the smear-imprint. The method of spectropolarimetry allows reliably accurately distinguishing the normal epithelium of the cervix from cancer of the cervix, and the parameters of linear dichroism during the spectropolarization study, reliably (р=0,001) differentiate between normal, adenocarcinoma and flat cell cancer of the cervix.
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O. Peresunko, Ju. Galushko, P. Riabyi, N. Horodynska, S. Yermolenko, D. Burkovets, and K. Chala "Spectrophotometry of native cytological smears from the cervix in cervical cancer screening", Proc. SPIE 12126, Fifteenth International Conference on Correlation Optics, 121260P (20 December 2021); https://doi.org/10.1117/12.2615512
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KEYWORDS
Dichroic materials
Connective tissue
Tumors
Absorbance
Optical fibers
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