Skull transmittance of transcranial red and near-infrared light in mouse models

Xi Li; Zhenping Xu; Miao Wang; Feifan Zhou

doi:10.1117/12.3003926

12 March 2024 Skull transmittance of transcranial red and near-infrared light in mouse models

Xi Li, Zhenping Xu, Miao Wang, Feifan Zhou

Proceedings Volume 12843, Biophotonics and Immune Responses XIX; 1284302 (2024) https://doi.org/10.1117/12.3003926
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Photobiomodulation (PBM) is a type of phototherapy that uses red or near-infrared (NIR) light to stimulate healing or regeneration of tissues with injury or degradation. In recent years, PBM has been successfully used in the treatment of nervous system diseases. However, the application of optical technology in non-invasive transcranial therapy is greatly limited by the high scattering and absorbance of head tissues including scalp and skull, as well as the transcranial spread properties of light with different parameters still remain unclear. Therefore, for realization of phototherapy for brain diseases, in-depth understanding of the transcranial penetrability of light through head tissues is urgently needed. In this study, the wavelength dependence of light transmittance through scalp and skull of mice was investigated using a transcranial laser at wavelengths of 660 nm or 808 nm, which provides reference for future research and application of transcranial PBM.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Xi Li, Zhenping Xu, Miao Wang, and Feifan Zhou "Skull transmittance of transcranial red and near-infrared light in mouse models", Proc. SPIE 12843, Biophotonics and Immune Responses XIX, 1284302 (12 March 2024); https://doi.org/10.1117/12.3003926

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available