A challenge for high-speed and high-resolution CT for extremities with clinical feasibility

Hiroki Kawashima; Katsuhiro Ichikawa

doi:10.1117/12.3004919

1 April 2024 A challenge for high-speed and high-resolution CT for extremities with clinical feasibility

Proceedings Volume 12925, Medical Imaging 2024: Physics of Medical Imaging; 129251W (2024) https://doi.org/10.1117/12.3004919
Event: SPIE Medical Imaging, 2024, San Diego, California, United States

Conference Poster

Abstract

Existing micro-CT systems can visualize the trabecular bone microstructure; however, its application is limited because of the small scan field of view and the long scan time for clinical use. We developed a high-resolution CT for human extremities (HRCTe) with clinical feasibility, which can achieve a spatial resolution of ~100μm and a short acquisition time of 6.5 seconds. A complementary metal-oxide-semiconductor x-ray detector with a 99μm pixel pitch and a compact x-ray tube with a focal spot size of 0.8mm were installed in the HRCTe. In order to maximize the performance of the x-ray tube and the detector, we introduced a low-magnification geometry. This resulted in an effective focal spot size of 0.14mm, ensuring the resolution performance of the pixel pitch at the iso-center of 81μm. The scan z-directional coverage was 50mm. For the technical assessment, modulation transfer function (MTF) and noise power spectrum (NPS) were measured using a wire phantom and a water phantom, respectively. A squared system performance function (SPF²) was calculated as MTF²/NPS. These results were compared with those measured using a high-resolution mode of a whole-body CT with a 0.25mm detector (WCT) and a dental CT (DCT). The 5%MTF of the HRCT, WCT, and DCT were approximately 3.8, 1.9, and 1.5mm^-1. The SPF² at 2.0mm^-1 of the developed CT was 260% higher than that of WCT. The trabecular bones in an anthropomorphic foot phantom were visualized much clearer with HRCTe than with both WCT and DCT.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Hiroki Kawashima and Katsuhiro Ichikawa "A challenge for high-speed and high-resolution CT for extremities with clinical feasibility", Proc. SPIE 12925, Medical Imaging 2024: Physics of Medical Imaging, 129251W (1 April 2024); https://doi.org/10.1117/12.3004919

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