In vivo animal follow-up studies on intrastromal surgery with near-infrared nanojoule femtosecond laser pulses

Baogui Wang; Iris Riemann; Karl-Juergen Halbhuber; Harald Schubert; Sigrun Kirste; Karsten Koenig

doi:10.1117/12.584193

15 April 2005 In vivo animal follow-up studies on intrastromal surgery with near-infrared nanojoule femtosecond laser pulses

Baogui Wang, Iris Riemann, Karl-Juergen Halbhuber, Harald Schubert, Sigrun Kirste, Karsten Koenig

Author Affiliations +

Proceedings Volume 5695, Optical Interactions with Tissue and Cells XVI; (2005) https://doi.org/10.1117/12.584193
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

We report on the histological results of in-vivo animal follow-up studies on refractive femtosecond laser surgery. Non-invasive flap-free intrastromal ablation as well as flap generation has been performed with MHz nanojoule near infrared femtosecond laser pulses. In particular, the dynamics of corneal wound healing have been studied. Wound-healing effects could be detected up to 90 days post-operation in the case of lasermediated flap generation. The flap-free intrastromal cavity was identified until the 28th day post-treatment. Interestingly, eosinophil granulocytes were observed. The follow-up studies confirmed that the near infrared femtosecond laser at near-nanojoule pulse energy is a highly precise and an attractive tool for intraocular refractive surgery, especially for flap-free intrastromal surgery.

Citation Download Citation

Baogui Wang, Iris Riemann, Karl-Juergen Halbhuber, Harald Schubert, Sigrun Kirste, and Karsten Koenig "In vivo animal follow-up studies on intrastromal surgery with near-infrared nanojoule femtosecond laser pulses", Proc. SPIE 5695, Optical Interactions with Tissue and Cells XVI, (15 April 2005); https://doi.org/10.1117/12.584193

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available