Intravascular OCT polarimetry: Progress, prospects, and challenges

Martin Villiger; Kenichiro Otsuka; Brett Bouma

doi:10.1117/12.2619302

7 March 2022 Intravascular OCT polarimetry: Progress, prospects, and challenges

Martin Villiger, Kenichiro Otsuka, Brett Bouma

Proceedings Volume PC11936, Diagnostic and Therapeutic Applications of Light in Cardiology 2022; PC1193601 (2022) https://doi.org/10.1117/12.2619302
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Intravascular polarimetry with optical coherence tomography measures polarization effects arising from tissue anisotropy. This affords insight into the microstructure and physical orientation of collagen or smooth muscle cells and provides metrics to quantify scattering properties of lipid-rich plaques. We present insights from clinical pilot studies with intravascular polarimetry, discuss its prospects for improving our mechanistic understanding of plaque progression and help patient management, and explain our progress with alleviating the hardware requirements to enable intravascular polarimetry.

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Martin Villiger, Kenichiro Otsuka, and Brett Bouma "Intravascular OCT polarimetry: Progress, prospects, and challenges", Proc. SPIE PC11936, Diagnostic and Therapeutic Applications of Light in Cardiology 2022, PC1193601 (7 March 2022); https://doi.org/10.1117/12.2619302

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KEYWORDS

Polarimetry

Optical coherence tomography

Anisotropy

Collagen

Optical testing

Polarization

Scattering

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