Lissajous OCT angiography for large field-of-view, high-dense spatial sampling, and long-duration microvasculature imaging

Shuichi Makita; Masahiro Miura; Shinnosuke Azuma; Toshihiro Mino; Tatsuo Yamaguchi; Yoshiaki Yasuno

doi:10.1117/12.2647849

17 March 2023 Lissajous OCT angiography for large field-of-view, high-dense spatial sampling, and long-duration microvasculature imaging

Shuichi Makita, Masahiro Miura, Shinnosuke Azuma, Toshihiro Mino, Tatsuo Yamaguchi, Yoshiaki Yasuno

Author Affiliations +

Proceedings Volume PC12360, Ophthalmic Technologies XXXIII; PC1236006 (2023) https://doi.org/10.1117/12.2647849
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

OCT-based angiography (OCTA) enables imaging of retinal microvasculature. However, involuntary movements of subjects prevent obtaining microvasculature with a large field of view (FOV) with high-dense spatial sampling. Meanwhile, a short duration for blood flow detection results in unstable vasculature contrast. By combining a Lissajous scan and a slow shift, Lissajous OCT enables compensating eye movements, and then the FOV will be extended while the spatial sampling density is preserved by the slow shift. The Lissajous scan allows a long blood flow detection duration. In vivo human eye microvasculature imaging using the convolutional Lissajous OCTA is investigated with several disease eyes.

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Shuichi Makita, Masahiro Miura, Shinnosuke Azuma, Toshihiro Mino, Tatsuo Yamaguchi, and Yoshiaki Yasuno "Lissajous OCT angiography for large field-of-view, high-dense spatial sampling, and long-duration microvasculature imaging", Proc. SPIE PC12360, Ophthalmic Technologies XXXIII, PC1236006 (17 March 2023); https://doi.org/10.1117/12.2647849

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