Ultrahigh-resolution optoacoustic tomography in vivo using silicon photonics

Yoav Hazan; Ahiad Levi; Michael Nagli; Amir Rosenthal

doi:10.1117/12.2651703

9 March 2023 Ultrahigh-resolution optoacoustic tomography in vivo using silicon photonics

Yoav Hazan, Ahiad Levi, Michael Nagli, Amir Rosenthal

Proceedings Volume PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023; PC123791N (2023) https://doi.org/10.1117/12.2651703
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

A new ultrasound-detection technology is developed for ultrahigh-resolution optoacoustic tomography and is experimentally demonstrated with bandwidths exceeding 200 MHz and lateral resolutions beyond 20 µm. Our technology is based on an optical resonator fabricated in a silicon-photonics platform, which is coated by a sensitivity-enhancing polymer, which also eliminates the parasitic effect of surface acoustic waves. Further improvement in sensitivity is achieved by a low-noise interferometric setup, which eliminates the effect of laser frequency noise on the measurement. In vivo optoacoustic tomography is performed on a mouse ear, revealing its vasculature at detail that has been previously reserved to optoacoustic microscopy.

Conference Presentation

Citation Download Citation

Yoav Hazan, Ahiad Levi, Michael Nagli, and Amir Rosenthal "Ultrahigh-resolution optoacoustic tomography in vivo using silicon photonics", Proc. SPIE PC12379, Photons Plus Ultrasound: Imaging and Sensing 2023, PC123791N (9 March 2023); https://doi.org/10.1117/12.2651703

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KEYWORDS

Optoacoustics

Tomography

In vivo imaging

Silicon photonics

Acoustics

Image resolution

Microscopy

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