Characterizing femtosecond laser effects on collagen (Conference Presentation)

Po-Yi Lee; Yuankai Lu; Marissa Quinn; Susannah Waxman; Fengting Ji; Gregory A. Gibson; Bin Yang; Ian A. Sigal

doi:10.1117/12.2647185

15 March 2023 Characterizing femtosecond laser effects on collagen (Conference Presentation)

Po-Yi Lee, Yuankai Lu, Marissa Quinn, Susannah Waxman, Fengting Ji, Gregory A. Gibson, Bin Yang, Ian A. Sigal

Proceedings Volume PC12381, Optical Elastography and Tissue Biomechanics X; PC123810H (2023) https://doi.org/10.1117/12.2647185
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Collagen crosslinking and degradation have been associated with changes in tissue stiffness. Although femtosecond laser irradiation might induce either collagen crosslinking or collagen degradation, the photomodulation effects are still unclear. Our goal was to characterize effects of photomodulation. We found that collagen crosslinking and degradation were related to the number of treatments, and photomodulation-involved reactants diffuse. The precision of photomodulation was at the micrometer level in both lateral and axial directions. Polarized light microscopy shows no change in collagen architecture in the treatment boundary and without the production of damaging thermoacoustic effects.

Conference Presentation

Citation Download Citation

Po-Yi Lee, Yuankai Lu, Marissa Quinn, Susannah Waxman, Fengting Ji, Gregory A. Gibson, Bin Yang, and Ian A. Sigal "Characterizing femtosecond laser effects on collagen (Conference Presentation)", Proc. SPIE PC12381, Optical Elastography and Tissue Biomechanics X, PC123810H (15 March 2023); https://doi.org/10.1117/12.2647185

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available