All-optical optoacoustic micro-tomography based on silicon-photonics acoustic detector in reflection mode

Tamar Harary; Yoav Hazan; Amir Rosenthal

doi:10.1117/12.2691550

13 March 2024 All-optical optoacoustic micro-tomography based on silicon-photonics acoustic detector in reflection mode

Tamar Harary, Yoav Hazan, Amir Rosenthal

Proceedings Volume PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024; PC128421M (2024) https://doi.org/10.1117/12.2691550
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

High-resolution optoacoustic imaging is conventionally performed using a microscopy setup where a strongly focused ultrasound transducer samples the image object point-by-point. Although recent advancements in miniaturized ultrasound detectors enables to achieve microscopic resolution with an unfocused detector in a tomographic configuration, such an approach requires illuminating the entire object, leading to an inefficient use of the optical power, and imposing a trans-illumination configuration that is limited to thin objects. We developed an optoacoustic micro-tomography system in an epi-illumination configuration, in which the illumination is scanned with the detector. The system is demonstrated in phantoms for imaging depths of up to 5 mm and in vivo for imaging the vasculature of a mouse ear. Although image-formation in optoacoustic tomography generally requires static illumination, our numerical simulations and experimental measurements show that this requirement is relaxed in practice due to light diffusion, which homogenizes the fluence in deep tissue layers.

Conference Presentation

Citation Download Citation

Tamar Harary, Yoav Hazan, and Amir Rosenthal "All-optical optoacoustic micro-tomography based on silicon-photonics acoustic detector in reflection mode", Proc. SPIE PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024, PC128421M (13 March 2024); https://doi.org/10.1117/12.2691550

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