CONFERENCE PROCEEDINGS
Advanced Search
Home > Proceedings > Volume PC12860 > Article
Presentation
13 March 2024 Graphene-based surface-enhanced Raman spectroscopy (SERS) for enzyme-linked immunosorbent assay (ELISA)
Takashi Uchino
Author Affiliations +
Proceedings Volume PC12860, Plasmonics in Biology and Medicine XXI; PC1286005 (2024) https://doi.org/10.1117/12.2691655
Event: SPIE BiOS, 2024, San Francisco, California, United States
Abstract
We develop highly sensitive graphene-based surface-enhanced Raman spectroscopy (SERS) substrates where monolayer graphene is coated on the Ag/mica substrates. SERS has attracted attention in biosensor applications that allow label-free detection with high specificity. Recently two-dimensional (2D) materials such as graphene, h-BN, and MoS2 have been explored as a new platform for SERS substrates. These materials have the advantage of being non-metal, with excellent biological compatibility, endurance, and uniformity characteristics. Then, we study the stacked SERS substrates where monolayer graphene is transferred on the mica substrates with single-crystal Ag thin films deposited on the back to improve SERS efficiency. The fabricated SERS substrates show stronger Raman signals than the mica substrates with Ag thin films. Then sandwich enzyme-linked immunosorbent assay (ELISA) is fabricated on the SERS substrates to detect bovine interleukin-6 (IL-6), inciting bovine mastitis.
Conference Presentation
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Citation Download Citation
Takashi Uchino "Graphene-based surface-enhanced Raman spectroscopy (SERS) for enzyme-linked immunosorbent assay (ELISA)", Proc. SPIE PC12860, Plasmonics in Biology and Medicine XXI, PC1286005 (13 March 2024); https://doi.org/10.1117/12.2691655
ACCESS THE FULL ARTICLE
ORGANIZATIONAL
Sign in with credentials provided by your organization.
INSTITUTIONAL
Select your institution to access the SPIE Digital Library.
SELECT YOUR INSTITUTION
PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
PERSONAL SIGN IN
No SPIE Account? Create one
PURCHASE THIS CONTENT
SUBSCRIBE TO DIGITAL LIBRARY
50 downloads per 1-year subscription
Members: $195
Non-members: $335 ADD TO CART
25 downloads per 1 - year subscription
Members: $145
Non-members: $250 ADD TO CART
PURCHASE SINGLE ARTICLE
Includes PDF, HTML & Video, when available
Members: $17.00
Non-members: $21.00 ADD TO CART
PROCEEDINGS
 PRESENTATION
WATCH
PRESENTATION SAVE TO MY LIBRARY
GET CITATION
Advertisement
Advertisement
KEYWORDS
Surface enhanced Raman spectroscopy
Graphene
Mica
Silver
Monolayers
Localized surface plasmon resonances
Raman spectroscopy
RELATED CONTENT
Subscribe to Digital Library
Receive Erratum Email Alert
Back to Top