Open Access
4 August 2016 High-temporal-resolution, full-field optical angiography based on short-time modulation depth for vascular occlusion tests
Riwei Liao, Mingyi Wang, Dingan Han, Zuohua Huang, Yaguang Zeng
Author Affiliations +
Abstract
We developed high-temporal-resolution, full-field optical angiography for use in vascular occlusion tests (VOTs). In the proposed method, undersampled signals are acquired by a high-speed digital camera that separates the dynamic and static speckle signals. The two types of speckle signal are used to calculate the short-time modulation depth (STMD) of each of the camera pixels. STMD is then used to realize high-temporal-resolution, full-field optical angiography. Phantom and biological experiments conducted and demonstrated the feasibility of using our proposed method to perform VOTs and to study the reaction kinetics in microfluidic systems.
© 2016 Society of Photo-Optical Instrumentation Engineers (SPIE) 1083-3668/2016/$25.00 © 2016 SPIE
Riwei Liao, Mingyi Wang, Dingan Han, Zuohua Huang, and Yaguang Zeng "High-temporal-resolution, full-field optical angiography based on short-time modulation depth for vascular occlusion tests," Journal of Biomedical Optics 21(8), 086002 (4 August 2016). https://doi.org/10.1117/1.JBO.21.8.086002
Published: 4 August 2016
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CITATIONS
Cited by 2 scholarly publications.
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KEYWORDS
Speckle

Angiography

Cameras

Modulation

Particles

Biomedical optics

Blood circulation

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