Design of a multifiber light delivery system for photoacoustic-guided surgery

Blackberrie Eddins; Muyinatu A. Lediju Bell

doi:10.1117/1.JBO.22.4.041011

13 January 2017 Design of a multifiber light delivery system for photoacoustic-guided surgery

Blackberrie Eddins, Muyinatu A. Lediju Bell

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Journal of Biomedical Optics, Vol. 22, Issue 4, 041011 (January 2017). https://doi.org/10.1117/1.JBO.22.4.041011

Abstract

This work explores light delivery optimization for photoacoustic-guided minimally invasive surgeries, such as the endonasal transsphenoidal approach. Monte Carlo simulations were employed to study three-dimensional light propagation in tissue, comprising one or two 4-mm diameter arteries located 3 mm below bone, an absorbing metallic drill contacting the bone surface, and a single light source placed next to the 2.4-mm diameter drill shaft with a 2.9-mm diameter spherical drill tip. The optimal fiber distance from the drill shaft was determined from the maximum normalized fluence to the underlying artery. Using this optimal fiber-to-drill shaft distance, Zemax simulations were employed to propagate Gaussian beams through one or more 600 micron-core diameter optical fibers for detection on the bone surface. When the number of equally spaced fibers surrounding the drill increased, a single merged optical profile formed with seven or more fibers, determined by thresholding the resulting light profile images at 1/e times the maximum intensity. We used these simulations to inform design requirements, build a one to seven multifiber light delivery prototype to surround a surgical drill, and demonstrate its ability to simultaneously visualize the tool tip and blood vessel targets in the absence and presence of bone. The results and methodology are generalizable to multiple interventional photoacoustic applications.

CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Blackberrie Eddins and Muyinatu A. Lediju Bell "Design of a multifiber light delivery system for photoacoustic-guided surgery," Journal of Biomedical Optics 22(4), 041011 (13 January 2017). https://doi.org/10.1117/1.JBO.22.4.041011

Received: 1 September 2016; Accepted: 15 December 2016; Published: 13 January 2017

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