Dr. Iacovos S. Kyprianou Profile

Dr. Iacovos S. Kyprianou

Research Fellow/Visiting Scientist at US Food and Drug Administration

SPIE Involvement:

Author

Publications (23)

Proceedings Article | 17 March 2011 Paper

A comparison of methods for estimating the line spread function of a CT imaging system

Samir Abboud, Kristina Lee, Kaleb Vinehout, Sophie Paquerault, Iacovos Kyprianou

Proceedings Volume 7961, 79615V (2011) https://doi.org/10.1117/12.877665

KEYWORDS: Imaging systems, Modulation transfer functions, Point spread functions, Computed tomography, Polymethylmethacrylate, Aluminum, Molybdenum, Image quality, X-ray computed tomography, Signal attenuation

Read Abstract +

Proceedings Article | 17 March 2011 Paper

Investigation of a method to estimate the MTF and NPS of CT towards creating an international standard

Claudia Brunner, Bernhard Renger, Christoph Hoeschen, Iacovos Kyprianou

Proceedings Volume 7961, 79613C (2011) https://doi.org/10.1117/12.877657

KEYWORDS: Modulation transfer functions, Signal to noise ratio, Computed tomography, Image quality standards, Scanners, Medical imaging, Spatial frequencies, Imaging systems, Point spread functions, Physics

Read Abstract +

Proceedings Article | 17 March 2011 Paper

Energy deposition in the breast during CT scanning: quantification and implications for dose reduction

Franco Rupcich, Iacovos Kyprianou, Andreu Badal, Taly Schmidt

Proceedings Volume 7961, 796128 (2011) https://doi.org/10.1117/12.878861

KEYWORDS: Breast, Monte Carlo methods, Photon transport, Computed tomography, Sensors, Bismuth, Cancer, X-rays, Tissues, Tissue optics

Read Abstract +

Proceedings Article | 23 March 2010 Paper

Noise characterization of computed tomography using the covariance matrix

Claudia Brunner, Stefanie Hurowitz, Samir Abboud, Christoph Hoeschen, Iacovos Kyprianou

Proceedings Volume 7622, 76224Z (2010) https://doi.org/10.1117/12.845494

KEYWORDS: Signal to noise ratio, Computed tomography, Imaging systems, Medical imaging, Scanners, Physics, Current controlled current source, Interference (communication), Computing systems, Polymethylmethacrylate

Read Abstract +

Proceedings Article | 23 March 2010 Paper

Designing a phantom for dose evaluation in multi-slice CT

Samir Abboud, Andreu Badal, Stanley Stern, Iacovos Kyprianou

Proceedings Volume 7622, 762232 (2010) https://doi.org/10.1117/12.844355

KEYWORDS: Monte Carlo methods, Convolution, Scanners, Computed tomography, Optical simulations, Polymethylmethacrylate, Mathematical modeling, Ionization, X-ray computed tomography, Collimation

Read Abstract +

Proceedings Article | 23 March 2010 Paper

Fast cardiac CT simulation using a graphics processing unit-accelerated Monte Carlo code

Andreu Badal, Iacovos Kyprianou, Diksha Sharma, Aldo Badano

Proceedings Volume 7622, 762231 (2010) https://doi.org/10.1117/12.845562

KEYWORDS: Monte Carlo methods, Computer simulations, Sensors, X-rays, Computed tomography, Image compression, X-ray computed tomography, Particles, Electrons, CT reconstruction

Read Abstract +

Proceedings Article | 22 March 2010 Paper

Task specific evaluation of clinical full field digital mammography systems using the Fourier definition of the Hotelling observer SNR

Haimo Liu, Aldo Badano, Luis Benevides, Kish Chakrabarti, Richard Kaczmarek, Iacovos Kyprianou

Proceedings Volume 7622, 762212 (2010) https://doi.org/10.1117/12.845509

KEYWORDS: Signal to noise ratio, Image processing, Imaging systems, Modulation transfer functions, Image acquisition, Sensors, Digital mammography, Breast, Mammography, Solids

Read Abstract +

Proceedings Article | 14 March 2009 Paper

Noise and signal detection in digital x-ray detectors using the spatial definition of SNR

Iacovos Kyprianou, Aldo Badano, Subok Park, Haimo Liu, Kyle Myers

Proceedings Volume 7258, 725819 (2009) https://doi.org/10.1117/12.813843

KEYWORDS: Signal to noise ratio, Sensors, Imaging systems, Modulation transfer functions, Interference (communication), Quantum electronics, Signal detection, X-ray detectors, Digital x-ray imaging, Arteries

Read Abstract +

Proceedings Article | 13 March 2009 Paper

A task-based evaluation method for x-ray breast imaging systems using variable-background phantoms

Subok Park, Haimo Liu, Robert Jennings, Robert Leimbach, Iacovos Kyprianou, Aldo Badano, Kyle Myers

Proceedings Volume 7258, 72581L (2009) https://doi.org/10.1117/12.813572

KEYWORDS: Imaging systems, X-rays, X-ray imaging, 3D image processing, Signal to noise ratio, Breast imaging, Mammography, Signal detection, Breast, Optical spheres

Read Abstract +

Proceedings Article | 11 March 2009 Paper

SKE/BKE task-based methodology for calculating Hotelling observer SNR in mammography

Haimo Liu, Iacovos Kyprianou, Aldo Badano, Kyle Myers, Robert Jennings, Subok Park, Richard Kaczmarek, Kish Chakrabarti

Proceedings Volume 7258, 72581D (2009) https://doi.org/10.1117/12.813833

KEYWORDS: Signal to noise ratio, Sensors, Imaging systems, Mammography, Signal detection, Polymethylmethacrylate, X-rays, X-ray detectors, Interference (communication), Laser range finders

Read Abstract +

Proceedings Article | 18 March 2008 Paper

An efficient depth- and energy-dependent Monte Carlo model for columnar CsI detectors

Iacovos Kyprianou, Gabriel Brackman, Kyle Myers, Andreu Badal, Aldo Badano

Proceedings Volume 6913, 69130O (2008) https://doi.org/10.1117/12.772878

KEYWORDS: Sensors, Monte Carlo methods, Scintillators, X-rays, Photon transport, Particles, X-ray detectors, X-ray optics, X-ray imaging, Imaging systems

Read Abstract +

Proceedings Article | 21 March 2007 Paper

Monte Carlo simulated coronary angiograms of realistic anatomy and pathology models

Iacovos Kyprianou, Andreu Badal, Aldo Badano, Diemphuc Banh, Melanie Freed, Kyle Myers, Laura Thompson

Proceedings Volume 6509, 65090O (2007) https://doi.org/10.1117/12.709553

KEYWORDS: Arteries, Monte Carlo methods, Angiography, Heart, Natural surfaces, Imaging systems, Particles, Tissues, X-rays, Pathology

Read Abstract +

Proceedings Article | 19 March 2007 Paper

Monte Carlo package for simulating radiographic images of realistic anthropomorphic phantoms described by triangle meshes

Andreu Badal, Iacovos Kyprianou, Aldo Badano, Josep Sempau, Kyle Myers

Proceedings Volume 6510, 65100Z (2007) https://doi.org/10.1117/12.707934

KEYWORDS: Particles, Monte Carlo methods, Computer simulations, Sensors, Angiography, X-ray imaging, Imaging systems, Data modeling, Medical imaging, Electrons

Read Abstract +

Proceedings Article | 13 March 2007 Paper

A method to estimate the point response function of digital x-ray detectors from edge measurements

Iacovos Kyprianou, Aldo Badano, Brandon Gallas, Kyle Myers

Proceedings Volume 6510, 65100B (2007) https://doi.org/10.1117/12.709517

KEYWORDS: Sensors, Laser range finders, X-rays, Monte Carlo methods, X-ray detectors, Scintillators, Dysprosium, Imaging systems, X-ray optics, Optical simulations

Read Abstract +

Proceedings Article | 13 March 2007 Paper

Validation of simulated point response of columnar phosphor screens

Aldo Badano, Iacovos Kyprianou, Katherine Tang, Anindita Saha

Proceedings Volume 6510, 65100Y (2007) https://doi.org/10.1117/12.709686

KEYWORDS: Monte Carlo methods, Sensors, X-rays, Imaging systems, Systems modeling, X-ray detectors, Optimization (mathematics), CCD cameras, Fiber optics, Optical simulations

Read Abstract +

Proceedings Article | 8 March 2007 Paper

Morphology-based three-dimensional segmentation of coronary artery tree from CTA scans

Diem Phuc Banh, Iacovos Kyprianou, Sophie Paquerault, Kyle Myers

Proceedings Volume 6512, 65122I (2007) https://doi.org/10.1117/12.710122

KEYWORDS: Arteries, Image segmentation, Heart, 3D modeling, 3D image processing, Algorithm development, Medical imaging, Reconstruction algorithms, Image processing, Tissues

Read Abstract +

Proceedings Article | 13 March 2006 Paper

Gender-specific statistical models of pathological coronary arteries for generating simulated angiograms

Iacovos Kyprianou, Laura Thompson, Diem Phuc Banh, William Pritchard, John Karanian, Lee Rosen, Kyle Myers

Proceedings Volume 6143, 61432K (2006) https://doi.org/10.1117/12.654383

KEYWORDS: Arteries, Angiography, Heart, Monte Carlo methods, Data modeling, Solid modeling, Imaging systems, Blood, Particles, Statistical analysis

Read Abstract +

Cardiovascular disease is considered the leading cause of death in the US, accounting for 38% of all deaths. There are gender differences in the size of coronary arteries and in the character and location of atherosclerotic lesions that affect the detection of coronary artery disease with the medical imaging modalities currently used (e.g. angiography, computed tomography). These differences also affect the safety and effectiveness of image-guided interventions using therapeutic devices. For the optimization of the medical imaging modalities used for this specific task we require the generation of clinically-realistic, gender-specific images of healthy and pathological coronary angiograms. For this purpose we have created a gender-specific statistical model of a pathological coronary artery tree. Starting from "healthy" heart-phantoms created from high resolution CT scans of cadaver hearts of both genders, the model uses prevalence data obtained from clinical studies of patients with significant (>50% stenosis) coronary artery disease (CAD). The model determines the plaque deposit locations and character (length, percent stenosis) for each case, based on a flow model. These data are then used to generate artificially diseased artery trees, embedded in a gender-specific torso model. Using an x-ray and optical photon Monte-Carlo simulation program, we then generate simulated angiograms exhibiting realistic disease patterns. The severity of each angiogram is determined from a set of rules that combines the geometrically increasing severity of lesions, the cumulative effects of multiple obstructions, the significance of their locations, the modifying influence of the collaterals, and the size and quality of the distal vessels. The simulated angiograms will consequently be read by model and human observers. The probability of detection derived in combination with the severity score will be used as a figure of merit for the patient- and gender-specific optimization of the imaging modality under investigation.

Proceedings Article | 2 March 2006 Paper

Three-dimensional columnar CsI model for x-ray imaging system simulations using MANTIS: validating for noise, blur, and light output

Aldo Badano, Iacovos Kyprianou, Josep Sempau

Proceedings Volume 6142, 61420W (2006) https://doi.org/10.1117/12.653309

KEYWORDS: X-rays, Sensors, Imaging systems, Monte Carlo methods, Photons, X-ray optics, X-ray imaging, Systems modeling, 3D modeling, Electrons

Read Abstract +

Proceedings Article | 2 March 2006 Paper

A practical method for measuring the H matrix of digital x-ray and cone beam CT imaging systems

Iacovos Kyprianou, Aldo Badano, Brandon Gallas, Subok Park, Kyle Myers

Proceedings Volume 6142, 61421U (2006) https://doi.org/10.1117/12.654374

KEYWORDS: Sensors, Imaging systems, X-rays, X-ray imaging, X-ray detectors, Calibration, Scintillators, Image sensors, Convolution, Ytterbium

Read Abstract +

Proceedings Article | 20 April 2005 Paper

Generalized performance evaluation of x-ray image intensifier compared with a microangiographic system

Girijesh Yadava, Iacovos Kyprianou, Stephen Rudin, Daniel Bednarek, Kenneth Hoffmann

Proceedings Volume 5745, (2005) https://doi.org/10.1117/12.594593

KEYWORDS: Sensors, Modulation transfer functions, Image intensifiers, Imaging systems, Spatial frequencies, X-ray imaging, X-rays, Silver, Radiation effects, X-ray detectors

Read Abstract +

Proceedings Article | 6 April 2005 Paper

Efficiency of the human observer compared to an ideal observer based on a generalized NEQ which incorporates scatter and geometric unsharpness: evaluation with a 2AFC experiment

Iacovos Kyprianou, Arundhuti Ganguly, Stephen Rudin, Daniel Bednarek, Brandon Gallas, Kyle Myers

Proceedings Volume 5749, (2005) https://doi.org/10.1117/12.595870

KEYWORDS: Sensors, Signal to noise ratio, Modulation transfer functions, Imaging systems, X-rays, Iodine, X-ray detectors, X-ray imaging, Signal detection, Spatial frequencies

Read Abstract +

Proceedings Article | 6 May 2004 Paper

Study of the generalized MTF and DQE for a new microangiographic system

Iacovos Kyprianou, Stephen Rudin, Daniel Bednarek, Kenneth Hoffmann

Proceedings Volume 5368, (2004) https://doi.org/10.1117/12.533512

KEYWORDS: Sensors, Modulation transfer functions, X-rays, X-ray detectors, Signal detection, Spatial frequencies, Head, Angiography, Scattering, Iodine

Read Abstract +

Proceedings Article | 3 May 2002 Paper

Micro-angiographic detector with fluoroscopic capability

Stephen Rudin, Ye Wu, Iacovos Kyprianou, Ciprian Ionita, Zhou Wang, Arundhuti Ganguly, Daniel Bednarek

Proceedings Volume 4682, (2002) https://doi.org/10.1117/12.465575

KEYWORDS: Sensors, Modulation transfer functions, X-rays, Charge-coupled devices, CCD cameras, CCD image sensors, Angiography, Fluoroscopy, X-ray imaging, Fiber optics

Read Abstract +

Showing 5 of 23 publications

Conference Committee Involvement (5)

Physics of Medical Imaging

11 February 2013 | Lake Buena Vista (Orlando Area), Florida, United States

Physics of Medical Imaging

5 February 2012 | San Diego, California, United States

Physics of Medical Imaging

13 February 2011 | Lake Buena Vista (Orlando), Florida, United States

Physics of Medical Imaging

15 February 2010 | San Diego, California, United States

Physics of Medical Imaging

9 February 2009 | Lake Buena Vista (Orlando Area), Florida, United States

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Keywords/Phrases

Search In:

Publication Years