Prof. Jeffrey C. Bamber Profile

Prof. Jeffrey C. Bamber

Team Leader at Institute of Cancer Research

SPIE Involvement:

Author

Publications (20)

Proceedings Article | 16 March 2020 Paper

Effects of radiation exposure on dermal collagen: A multi modal approach

Anna Maeva, Jeffrey Bamber, Inna Seviaryna, Colin Hopper, Conal Perrett, Laurent Bozec

Proceedings Volume 11319, 113190P (2020) https://doi.org/10.1117/12.2549843

KEYWORDS: Collagen, Skin, Atomic force microscopy, Signal attenuation, Tissues, Microscopy, Acoustics, Radiation effects, Biopsy, Polarized microscopy

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Proceedings Article | 4 March 2019 Presentation

International Photoacoustic Standardisation Consortium (IPASC): overview (Conference Presentation)

Sarah Bohndiek, Joanna Brunker, Janek Gröhl, Lina Hacker, James Joseph, William Vogt, Paolo Armanetti, Hisham Assi, Jeffrey Bamber, Paul Beard, Thomas Berer, Richard Bouchard, Kimberly Briggman, Lucia Cavigli, Bryan Clingman, Ben Cox, Adrien Desjardins, Andrew Heinmiller, Jeesong Hwang, Eno Hysi, Aoife Ivory, Jithin Jose, Thomas Kirchner, Jan Klohs, Lena Maier-Hein, Efthymios Maneas, Julia Mannheim, Srirang Manohar, Lacey McNally, Luca Menichetti, Steven Miller, Stefan Morscher, Ruiqing Ni, Yoko Okamura, Malini Olivo, Marty Pagel, Geoff Parker, Anna Pelagotti, Antonio Pifferi, Srinath Rajagopal, Fulvio Ratto, Daniel Razansky, Lisa Richards, Avihai Ron, Mithun Kuniyil Ajith Singh, Maximillian Waldner, Kun Wang, Lihong Wang, Wenfeng Xia, Bajram Zeqiri

Proceedings Volume 10878, 108781N (2019) https://doi.org/10.1117/12.2506044

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SPIE Journal Paper | 5 February 2018 Open Access

Further characterization of changes in axial strain elastograms due to the presence of slippery tumor boundaries

Christopher Uff, Leo Garcia, Jeremie Fromageau, Aabir Chakraborty, Neil Dorward, Jeffrey Bamber

JMI, Vol. 5, Issue 02, 021211, (February 2018) https://doi.org/10.1117/12.10.1117/1.JMI.5.2.021211

KEYWORDS: Tumors, Tissues, Finite element methods, Elastography, Ultrasonography, Brain, Motion models, Breast, Cancer, Diagnostics

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Elastography measures tissue strain, which can be interpreted under certain simplifying assumptions to be representative of the underlying stiffness distribution. This is useful in cancer diagnosis where tumors tend to have a different stiffness to healthy tissue and has also shown potential to provide indication of the degree of bonding at tumor–tissue boundaries, which is clinically useful because of its dependence on tumor pathology. We consider the changes in axial strain for the case of a symmetrical model undergoing uniaxial compression, studied by characterizing changes in tumor contrast transfer efficiency (CTE), inclusion to background strain contrast and strain contrast generated by slip motion, as a function of Young’s modulus contrast and applied strain. We present results from a finite element simulation and an evaluation of these results using tissue-mimicking phantoms. The simulation results show that a discontinuity in displacement data at the tumor boundary, caused by the surrounding tissue slipping past the tumor, creates a halo of “pseudostrain” across the tumor boundary. Mobile tumors also appear stiffer on elastograms than adhered tumors, to the extent that tumors that have the same Young’s modulus as the background may in fact be visible as low-strain regions, or those that are softer than the background may appear to be stiffer than the background. Tumor mobility also causes characteristic strain heterogeneity within the tumor, which exhibits low strain close to the slippery boundary and increasing strain toward the center of the tumor. These results were reproduced in phantom experiments. In addition, phantom experiments demonstrated that when fluid lubrication is present at the boundary, these effects become applied strain-dependent as well as modulus-dependent, in a systematic and characteristic manner. The knowledge generated by this study is expected to aid interpretation of clinical strain elastograms by helping to avoid misinterpretation as well as provide additional diagnostic criteria stated in the paper and stimulate further research into the application of elastography to tumor mobility assessment.

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Proceedings Article | 10 January 2017 Open Access

Erratum: Monte Carlo investigation of the dosimetric effect of the Autoscan ultrasound probe for guidance in radiotherapy

Michael Martyn, Tuathan O'Shea, Emma Harris, Jeffrey Bamber, Stephen Gilroy, Mark Foley

Proceedings Volume 9790, 97902A (2017) https://doi.org/10.1117/12.2271153

KEYWORDS: Lithium, Ultrasonography, Monte Carlo methods, Radiotherapy, Solids, Medical imaging, Tomography, Computed tomography, Cancer, Current controlled current source

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Proceedings Article | 1 April 2016 Paper

Monte Carlo investigation of the dosimetric effect of the Autoscan ultrasound probe for guidance in radiotherapy

Michael Martyn, Tuathan O'Shea, Emma Harris, Jeffrey Bamber, Stephen Gilroy, Mark Foley

Proceedings Volume 9790, 97900N (2016) https://doi.org/10.1117/12.2216653

KEYWORDS: Monte Carlo methods, Ultrasonography, Radiotherapy, Computer simulations, Computed tomography, Physics, Radiation dosimetry, Prostate, Data modeling, Solids, Head

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Proceedings Article | 6 March 2015 Paper

Combined correlation estimation of axial displacement in optical coherence elastography: assessment of axial displacement sensitivity performance relative to existing methods

A. Grimwood, A. Messa, J. Bamber

Proceedings Volume 9327, 93270W (2015) https://doi.org/10.1117/12.2079315

KEYWORDS: Current controlled current source, Phase shifts, Optical coherence tomography, Elastography, Coherence (optics), Signal to noise ratio, Signal analyzers, Correlation function, Actuators, Motion measurement

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Proceedings Article | 3 March 2014 Paper

Non-invasive molecular profiling of cancer using photoacoustic imaging of functionalized gold nanorods

Anant Shah, Erwin Alles, Carol Box, Suzanne Eccles, Simon Robinson, Nandita deSouza, Jeffrey Bamber

Proceedings Volume 8943, 89435G (2014) https://doi.org/10.1117/12.2038412

KEYWORDS: Gold, Photoacoustic spectroscopy, Cancer, Photoacoustic imaging, Profiling, Absorption, Receptors, Biopsy, Tissue optics, Nanorods

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SPIE Journal Paper | 16 December 2013 Open Access

Feasibility of skin surface elastography by tracking skin surface topography

Louise Coutts, Naomi Miller, Christopher Harland, Jeffrey Bamber

JBO, Vol. 18, Issue 12, 121513, (December 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.12.121513

KEYWORDS: Skin, Signal to noise ratio, Elastography, Spatial resolution, Silicon, Statistical analysis, Tissue optics, Tissues, In vivo imaging, Photography

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SPIE Journal Paper | 6 February 2013 Open Access

Vessel orientation-dependent sensitivity of optoacoustic imaging using a linear array transducer

Stefan Preisser, Nigel Bush, Andreas Gertsch-Grover, Sara Peeters, Arthur Bailey, Jeffrey Bamber, Martin Frenz, Michael Jaeger

JBO, Vol. 18, Issue 02, 026011, (February 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.2.026011

KEYWORDS: Blood vessels, Transducers, Acoustics, Tissues, In vivo imaging, Tissue optics, Signal detection, Imaging systems, Absorption, 3D image processing

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SPIE Journal Paper | 4 June 2012 Open Access

Deformation-compensated averaging for clutter reduction in epiphotoacoustic imaging in vivo

Michael Jaeger, David Harris-Birtill, Andreas Gertsch-Grover, Elizabeth O’Flynn, Jeffrey Bamber

JBO, Vol. 17, Issue 06, 066007, (June 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.6.066007

KEYWORDS: Ultrasonography, In vivo imaging, Tissues, Tissue optics, Photoacoustic spectroscopy, Acoustics, Photoacoustic imaging, Cancer, Neck, Laser tissue interaction

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Proceedings Article | 26 March 2011 Paper

A two-dimensional locally regularized strain estimation technique: preliminary clinical results for the assessment of benign and malignant breast lesions

Elisabeth Brusseau, Valérie Detti, Agnès Coulon, Emmanuèle Maissiat, Nawèle Boublay, Yves Berthezène, Jérémie Fromageau, Nigel Bush, Jeffrey Bamber

Proceedings Volume 7968, 79680J (2011) https://doi.org/10.1117/12.877683

KEYWORDS: Ultrasonography, Tissues, Breast, Image compression, Elastography, Data acquisition, Tumors, Cancer, Reliability, In vivo imaging

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Proceedings Article | 17 March 2011 Paper

Retaining axial-lateral orthogonality in steered ultrasound data to improve image quality in reconstructed lateral displacement data

Leo Garcia, Jérémie Fromageau, Richard Housden, Graham Treece, Christopher Uff, Jeffrey Bamber

Proceedings Volume 7961, 796151 (2011) https://doi.org/10.1117/12.878764

KEYWORDS: Ultrasonography, Tissues, Image quality, Point spread functions, Elastography, Image compression, Beam propagation method, Beam steering, Data acquisition, Scanners

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Proceedings Article | 23 February 2011 Paper

Optimising the illumination geometry of a clinical reflection mode photoacoustic scanner

David Birtill, Michael Jaeger, Andreas Gertsch, Jeffrey Bamber

Proceedings Volume 7899, 78993T (2011) https://doi.org/10.1117/12.875662

KEYWORDS: Photoacoustic spectroscopy, Point spread functions, Scanners, Tissue optics, Scattering, Fiber optics, Fiber optic illuminators, Photons, Ultrasonography, Current controlled current source

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Proceedings Article | 24 February 2010 Paper

Toward characterizing the size of microscopic optical absorbers using optoacoustic emission spectroscopy

A. Gertsch, N. Bush, D. C. Birtill, J. Bamber

Proceedings Volume 7564, 75641M (2010) https://doi.org/10.1117/12.844188

KEYWORDS: Transducers, Acoustics, Ultrasonography, Absorption, Tissue optics, Emission spectroscopy, Statistical analysis, Blood vessels, Imaging systems, Chemical elements

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Proceedings Article | 13 March 2009 Paper

Influence of inhomogeneity of optical absorbers on optoacoustic signals: a comparison between experiment and theory

A. Gertsch, M. Jaeger, N. Bush, M. Frenz, J. Bamber

Proceedings Volume 7265, 72650L (2009) https://doi.org/10.1117/12.813701

KEYWORDS: Absorption, Transducers, Target detection, Optical spheres, Tissue optics, Imaging systems, Ultrasonography, Acoustics, Spherical lenses, Computer simulations

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Proceedings Article | 8 October 2003 Paper

Development and design of a new spectral imaging system for melanoma research

Mary Haddock, Jeffrey Bamber, Robert Ott

Proceedings Volume 5141, (2003) https://doi.org/10.1117/12.500676

KEYWORDS: Spectral resolution, Diagnostics, Imaging spectroscopy, Imaging systems, Reflectivity, Melanoma, Spatial resolution, Spectrophotometry, Skin, Sensors

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Proceedings Article | 5 June 2002 Paper

Monitoring pigmented skin lesions

Vincent Wallace, Jeffery Bamber, Robert Ott, Diane Crawford, Peter Mortimer

Proceedings Volume 4623, (2002) https://doi.org/10.1117/12.469443

KEYWORDS: Melanoma, Skin, Diagnostics, Reflectivity, Artificial neural networks, Skin cancer, Visualization, Statistical analysis, Roads, Tissue optics

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Proceedings Article | 15 July 1999 Paper

Layered Monte Carlo model for the description of diffuse reflectance spectra from pigmented skin lesions

Vincent Wallace, Peter Mortimer, Robert Ott, Jeffery Bamber

Proceedings Volume 3597, (1999) https://doi.org/10.1117/12.356803

KEYWORDS: Skin, Optical properties, Melanoma, Monte Carlo methods, Reflectivity, Absorption, Scattering, Tissue optics, Blood, Photons

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Proceedings Article | 16 April 1997 Paper

Visual detectability of elastic contrast in real-time ultrasound images

Naomi Miller, Jeffery Bamber, Marvin Doyley, Martin Leach

Proceedings Volume 3036, (1997) https://doi.org/10.1117/12.271300

KEYWORDS: Tissues, Signal detection, Electroluminescence, Speckle, Ultrasonography, Visualization, Breast, Finite element methods, Error analysis, Transducers

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Proceedings Article | 22 September 1992 Paper

Data processing for 3-D ultrasound visualization of tumor anatomy and blood flow

Jeffery Bamber, R. Eckersley, P. Hubregtse, N. Bush, D. Bell, Diane Crawford

Proceedings Volume 1808, (1992) https://doi.org/10.1117/12.131117

KEYWORDS: Speckle, Visualization, Doppler effect, Volume rendering, Ultrasonography, Scattering, 3D visualizations, Binary data, Biomedical optics, Signal attenuation

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Showing 5 of 20 publications

Conference Committee Involvement (25)