Ms. Mengyuan Ke Profile

Mengyuan Ke

at Medizinische Univ. Wien

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Proceedings Article | 13 March 2024 Presentation + Paper

Wide dynamic range digital aberrometry and fast anterior-segment imaging with MHz SS-OCT

Mengyuan Ke, Abhishek Kumar, Björn Meyer, Thor Ansbæk, Rainer Leitgeb

Proceedings Volume 12830, 128300S (2024) https://doi.org/10.1117/12.3005622

KEYWORDS: Eye, Point spread functions, Eye models, Optical coherence tomography, Imaging systems, Wavefront errors, Vertical cavity surface emitting lasers, Anatomy

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Ocular aberrometry with a wide dynamic range for assessing vision performance and anterior segment imaging that provides anatomical details of the eye are both essential for vision research and clinical applications. Defocus error is a major limitation of digital wavefront aberrometry (DWA) as the blurring of the detected point spread function (PSF) results in a significant reduction of SNR beyond ±3 D range. With the aid of Badal-like precompensation of defocus, the dynamic defocus range of the captured aberrated PSFs can be effectively extended. We demonstrate a dual-modality MHz VCSEL-based swept-source OCT (SS-OCT) system, with an easy switch between DWA and OCT imaging mode. The system is capable of measuring aberrations with defocus dynamic range of D as well as providing fast anatomical imaging of the anterior segment at an A-scan rate of 1.6 MHz. The dual-mode system stands out for its modular design wherein simple hardware additions to an SS-OCT system enable the aberration measurement in DWA mode. In DWA mode, a diffraction-limited stationary spot is formed at the retina by a narrow illumination beam. The reflected light passes then through the full pupil of the eye, thereby the single path optical aberrations are captured. The OCT detection leads to volumetric PSFs, which are post-processed using the digital lateral shearing-based digital adaptive optics technique (DLS-DAO) to reconstruct the wavefront error. Capturing both optical and anatomical information of the eye can be potentially helpful for improved diagnosis and targeted treatment of ocular diseases.

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