We succeeded in fabricating ZnO microspheres with high sphericity by laser ablation in superfluid helium. Such
microspheres enable efficient lasing in the whole visible region due to defects with a CW laser at room temperature. The
lasing threshold is found to be around 100 W/cm2. This value is much smaller than those of the recent reports on the
lasing in ZnO microwire. Cathodoluminescence of single ZnO microspheres was also measured.