Currently, a number of techniques are used to access cell deformability. We study a novel silicon microchannels device for use in red blood cell deformability. The channels are produced in silicon substrate using microengineering technology. The microgrooves formed in the surface of a single-crystal silicon substrate. They were converted to channels by tightly covering them with an optical flat glass plate. An array of flow channels (number 950 in parallel) have typical dimensions of 5 micrometers width X 5.5 Xm depth, and 30 micrometers length. There the RBC's are forced to pass through channels. Thus, the microchannels are used to simulate human blood capillaries. It provides a specific measurement of individual cell in terms of both flow velocity profile and an index of cell volume while the cell flow through the channels. It dominates the complex cellular flow behavior, such as, the viscosity of whole blood is a nonlinear function of shear rate, index of filtration, etc.
Conference Committee Involvement (6)
Nano-, Bio-, Info-Tech Sensors and 3D Systems
26 March 2017 | Portland, Oregon, United States
Nano-, Bio-, Info-Tech Sensors and Systems
21 March 2016 | Las Vegas, Nevada, United States
Nano-, Bio-, Info-Tech Sensors and Systems
9 March 2015 | San Diego, California, United States
Nano-, Bio-, Info-Tech Sensors and Systems
10 March 2014 | San Diego, California, United States
Nano-, Bio-, Info-Tech Sensors and Systems
10 March 2013 | San Diego, California, United States
Nano-, Bio-, Info-Tech Sensors and Systems
12 March 2012 | San Diego, California, United States
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