Multifunctional nanoprobe to enhance the utility of optical based imaging techniques

Yeongri Jung; Guangying Guan; Chen-Wei Wei; Roberto Reif; Xiaohu Gao; Matthew O'Donnell; Ruikang K. Wang

doi:10.1117/1.JBO.17.1.016015

31 January 2012 Multifunctional nanoprobe to enhance the utility of optical based imaging techniques

Yeongri Jung, Guangying Guan, Chen-Wei Wei, Roberto Reif, Xiaohu Gao, Matthew O'Donnell, Ruikang K. Wang

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Journal of Biomedical Optics, Vol. 17, Issue 1, 016015 (January 2012). https://doi.org/10.1117/1.JBO.17.1.016015

Abstract

Several imaging modalities such as optical coherence tomography, photothermal, photoacoustic and magnetic resonance imaging, are sensitive to different physical properties (i.e. scattering, absorption and magnetic) that can provide contrast within biological tissues. Usually exogenous agents are designed with specific properties to provide contrast for these imaging methods. In nano-biotechnology there is a need to combine several of these properties into a single contrast agent. This multifunctional contrast agent can then be used by various imaging techniques simultaneously or can be used to develop new imaging modalities. We reported and characterized a multifunctional nanoparticle, made from gold nanoshells, which exhibits scattering, photothermal, photoacoustic, and magnetic properties.

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Yeongri Jung, Guangying Guan, Chen-Wei Wei, Roberto Reif, Xiaohu Gao, Matthew O'Donnell, and Ruikang K. Wang "Multifunctional nanoprobe to enhance the utility of optical based imaging techniques," Journal of Biomedical Optics 17(1), 016015 (31 January 2012). https://doi.org/10.1117/1.JBO.17.1.016015

Published: 31 January 2012

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