Dr. Hyun Wook Kang Profile

Dr. Hyun Wook Kang

at Pukyong National Univ

SPIE Involvement:

Conference Chair | Editor | Author

Area of Expertise:

Endoscopic Laser Treatment , Medical Delivery Device , Laser Tissue Interaction , Optical Disinfection , Wound Management , Endoscopic PBM

Websites:

Personal Website

Publications (59)

Proceedings Article | 13 March 2024 Presentation + Paper

Photothermal therapy-mediated with photodynamic therapy to improve prostate cancer treatment

Yeongeun Kim, Myungji Kang, Hyun Wook Kang

Proceedings Volume 12817, 1281708 (2024) https://doi.org/10.1117/12.3002039

KEYWORDS: Photodynamic therapy, Cell death, Prostate cancer, Animal model studies, Cancer, Tissues, Laser irradiation, Infrared cameras, In vivo imaging, In vitro testing

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Proceedings Article | 13 March 2024 Poster + Paper

Dual-function polymer-based antifog and antibacterial coating for endoscopic applications

Sivakumar Bose, Byeong-Il Lee, Hyun Wook Kang

Proceedings Volume 12817, 128170O (2024) https://doi.org/10.1117/12.3002046

KEYWORDS: Coating, Polyvinyl alcohol, Glasses, Endoscopy, Endoscopes, Polymers, Scanning electron microscopy, Biomedical applications, Visible radiation, Universities

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Proceedings Article | 13 March 2024 Presentation + Paper

Biomodulatory effect of a wavelength-dependent laser on prostate cancer in vitro and in vivo

Myungji Kang, Jihye Jo, Hyun Wook Kang

Proceedings Volume 12817, 1281702 (2024) https://doi.org/10.1117/12.3002047

KEYWORDS: Tumors, Laser irradiation, Prostate cancer, In vivo imaging, In vitro testing, Cancer, Laser therapeutics, Proteins, Modulation, Blood vessels

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Proceedings Article | 13 March 2024 Presentation + Paper

Feasibility of non-ablative photothermal 980nm laser endoluminal treatment for stress urinary incontinence

Hwarang Shin, Yeachan Lee, Seonghee Lim, Hyun Wook Kang

Proceedings Volume 12817, 1281705 (2024) https://doi.org/10.1117/12.3002041

KEYWORDS: Laser irradiation, Collagen, Animal model studies, Laser therapeutics, Muscles, Tissues, Animals, Safety, Numerical simulations

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Proceedings Article | 17 March 2023 Presentation

Translaryngeal photobiomodulation therapy using basket-integrated diffusing applicator for tracheostomy-associated fenestrated wound management

Yeachan Lee, Hyoung shin Lee, Seonghee Lim, Hwarang Shin, Sunju Oh, Hyun Wook Kang

Proceedings Volume PC12362, PC123620D (2023) https://doi.org/10.1117/12.2648146

KEYWORDS: Inflammation, Wound healing, Surgery, Modulation, In vivo imaging, Collagen

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Proceedings Article | 14 March 2023 Presentation + Paper

Sodium copper chlorophyllin mediated Interstitial PhotoDynamic Therapy (I-PDT) for Locally Advanced Cervical Cancer (LACC)

Yeachan Lee, Seong-Yeong Heo, Hwarang Shin, Seonghee Lim, Hyun Wook Kang

Proceedings Volume 12353, 1235307 (2023) https://doi.org/10.1117/12.2646284

KEYWORDS: Photodynamic therapy, Tumors, Cervical cancer, Tumor growth modeling, Toxicity, Tissues, Chlorophyll

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Proceedings Article | 14 March 2023 Presentation + Paper

Photothermal effects on urethral tissue for treatment of stress urinary incontinence

Hwarang Shin, Yeachan Lee, Seonghee Lim, Hyun Wook Kang

Proceedings Volume 12353, 1235304 (2023) https://doi.org/10.1117/12.2648136

KEYWORDS: Tissues, Muscles, Photothermal effect, Numerical simulations, Collagen, Temperature distribution, Laser irradiation, Balloons, Thermal effects, Partial differential equations

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Proceedings Article | 14 March 2023 Presentation + Paper

A combination of photothermal and photodynamic therapies for treatment of prostate cancer

Yeongeun Kim, Hyun Wook Kang

Proceedings Volume 12353, 1235305 (2023) https://doi.org/10.1117/12.2648551

KEYWORDS: Photodynamic therapy, Tumors, Prostate cancer, Cell death, In vitro testing, Cancer, Thermography, In vivo imaging, Hypoxia, Tissues

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Proceedings Article | 14 March 2023 Presentation + Paper

Balloon-assisted cylindrical laser ablation for urethral stenosis treatment

Seonghee Lim, Jiho Lee, Hyun Wook Kang

Proceedings Volume 12353, 1235309 (2023) https://doi.org/10.1117/12.2648137

KEYWORDS: Laser ablation, Tissues, Liver, Ablation, Laser irradiation, Safety

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Proceedings Article | 14 March 2023 Poster + Paper

Laser-induced thermal decomposition with Diffractive Lens Array (DLA) in ex vivo and in vivo skin tissue

Jiho Lee, Jongman Choi, Hyun Wook Kang

Proceedings Volume 12352, 123520E (2023) https://doi.org/10.1117/12.2648552

KEYWORDS: Diffractive optical elements, Tissues, Skin, Laser irradiation, Picosecond phenomena, Nd:YAG lasers, Medical research

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Proceedings Article | 7 February 2023 Presentation

Effects of laser pulse profiles on bubble dynamics

Steven Peng, Aditi Ray, Jian James Zhang, Thomas Hasenberg, Mike O'Brien, Hyun Wook Kang

Proceedings Volume PC11958, PC119580H (2023) https://doi.org/10.1117/12.2610040

KEYWORDS: Pulsed laser operation, Fiber lasers, Prototyping, Numerical simulations, Laser therapeutics, Laser systems engineering, Laser lithotripsy, Laser irradiation, Laser development, Laser ablation

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Proceedings Article | 7 March 2022 Presentation

Diffusing applicator-assisted photothermal therapy for enhanced treatment of tumor tissue

Van Gia Truong, Hyejin Kim, Van Nam Tran, Hyun Wook Kang

Proceedings Volume PC11958, PC119580J (2022) https://doi.org/10.1117/12.2612145

KEYWORDS: Tumors, Tissue optics, Cancer, In vivo imaging, Tumor growth modeling, Tissues, Thermal effects, Safety, Prostate, Optical components

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Proceedings Article | 7 March 2022 Presentation

Photobiomodulation therapy combined with phlorotannin for prevention of tracheal stenosis and granuloma

Yeachan Lee, Hyoung Shin Lee, Hyeonsoo Kim, Sunju Oh, Hyun Wook Kang

Proceedings Volume PC11958, PC119580C (2022) https://doi.org/10.1117/12.2612142

KEYWORDS: Endoscopy, Modulation, Continuous wave operation, Collagen, Bladder

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Proceedings Article | 7 March 2022 Presentation

Photobiomodulative effects of laser wavelength on tumor tissue

Hyejin Kim, Yeongeun Kim, Hyun Wook Kang

Proceedings Volume PC11958, PC119580G (2022) https://doi.org/10.1117/12.2612146

KEYWORDS: Tumors, Cancer, Oncology, Laser tissue interaction, Ultraviolet radiation, Hypoxia, Safety, Photodynamic therapy, Near infrared, Laser therapeutics

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Proceedings Article | 7 March 2022 Presentation

Rapid evaluations of laser cleaning efficacy on mature biofilm with microfluidic-powered optical platform

Van Nam Tran, Won Han, Fazlurrahman Khan, Van Gia Truong, Joong Ho Shin, Young Mog Kim, Hyun Wook Kang

Proceedings Volume PC11958, PC119580F (2022) https://doi.org/10.1117/12.2612147

KEYWORDS: Laser irradiation, Microfluidics, Laser development, Environmental monitoring, Bacteria, 3D printing

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Proceedings Article | 7 March 2022 Poster + Presentation

Photothermal therapy combined with multi-lens array (MLA) and power modulation for treatment of prostate tumor

Yeongeun Kim, Hyejin Kim, Hyun Wook Kang

Proceedings Volume PC11958, PC119580O (2022) https://doi.org/10.1117/12.2610550

KEYWORDS: Modulation, Tumors, Prostate, Cancer, Prostate cancer, Infrared cameras, In vivo imaging, Tissues, Oncology, Mouse models

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Proceedings Article | 7 March 2022 Poster + Presentation

Automated recognition and quantitative analysis of scar tissue using deep learning

Luluil Maknuna, Hyeonsoo Kim, Yeachan Lee, Yoon Jin Choi, Hyunjung Kim, Myunggi Yi, Hyun Wook Kang

Proceedings Volume PC11958, PC119580Q (2022) https://doi.org/10.1117/12.2610591

KEYWORDS: Tissues, Quantitative analysis, Image segmentation, Image analysis, Collagen, Analytical research, Wound healing, Neural networks, Convolution

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Proceedings Article | 12 January 2022 Paper

Deep-learning-based characterization of laser-induced scar tissue

Luluil Maknuna, Hyeonsoo Kim, Yeachan Lee, Yoonjin Choi, Hyunjung Kim, Myunggi Yi, Hyun Wook Kang

Proceedings Volume 12159, 121590G (2022) https://doi.org/10.1117/12.2626273

KEYWORDS: Tissues, Collagen, RGB color model, Laser tissue interaction, Image segmentation, Wound healing, Convolution, Visualization, Skin, Biomedical engineering

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Proceedings Article | 12 January 2022 Paper

Novel endoscopic laser treatment of common bile duct stenosis using balloon catheter-integrated diffusing applicator (BCDA)

Van Gia Truong, Seok Jeong, Yeachan Lee, Sung Min Kim, Hyun Wook Kang

Proceedings Volume 12159, 1215904 (2022) https://doi.org/10.1117/12.2624568

KEYWORDS: Endoscopy, Laser tissue interaction, Laser ablation, Laser therapeutics

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Proceedings Article | 12 January 2022 Paper

Phlorotannin-combined photobiomodulation for prevention of tracheal stomal stenosis post-tracheostomy: in-vitro and in-vivo evaluations

Yeachan Lee, Hyoung Shin Lee, Hyeonsoo Kim, Hyun Wook Kang

Proceedings Volume 12159, 121590D (2022) https://doi.org/10.1117/12.2626052

KEYWORDS: Tissues, In vitro testing, Modulation, Medical research, Collagen, Safety, Continuous wave operation, Biomedical optics, Biomedical engineering

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Proceedings Article | 12 January 2022 Paper

Optical and thermal effects of air trap on cylindrical laser treatment of tubular stenosis

Seonghee Lim, Van Gia Truong, Hyun Wook Kang

Proceedings Volume 12159, 121590E (2022) https://doi.org/10.1117/12.2626054

KEYWORDS: Laser therapeutics, Laser tissue interaction, Tissues, Thermal effects, Laser ablation

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Proceedings Article | 12 January 2022 Paper

Stimulatory effects of laser wavelengths on proliferation and angiogenesis of colon cancer: in-vitro and in-vivo evaluations

Hyejin Kim, Yeongeun Kim, Hyun Wook Kang

Proceedings Volume 12159, 121590F (2022) https://doi.org/10.1117/12.2626057

KEYWORDS: Tumors, In vivo imaging, Near infrared, In vitro testing, Cancer, Colorectal cancer, Proteins, Laser therapeutics, Safety, Hypoxia

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Proceedings Article | 12 January 2022 Paper

Picosecond laser irradiation by using micro-lens arrays and diffractive optical elements on different skin types

Hyeonsoo Kim, Jongman Choi, Hyun Wook Kang

Proceedings Volume 12159, 121590H (2022) https://doi.org/10.1117/12.2626644

KEYWORDS: Skin, Diffractive optical elements, Picosecond phenomena, Laser tissue interaction, Tissues, Tissue optics, Laser optics, Optical arrays, Laser scattering, Ultraviolet radiation

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Proceedings Article | 12 January 2022 Paper

Opto-chemical disinfection of bacterial pathogens in mature biofilms grown in flexible endoscope

Van Nam Tran, Periaswamy Sivagnanam Saravana, Suhyun Park, Fazlurrahman Khan, Van Gia Truong, Seok Jeong, Don Haeng Lee, Byung-Soo Chun, Young Mog Kim, Hyun Wook Kang

Proceedings Volume 12159, 121590C (2022) https://doi.org/10.1117/12.2626049

KEYWORDS: Endoscopes, Scanning electron microscopy, Infrared radiation, Bacteria, Pathogens, Temperature metrology, Proteins, Infrared imaging, Biomimetics, Visible radiation

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Proceedings Article | 7 December 2021 Paper

Micro-lens arrays (MLA)-assisted fractional photothermal therapy for effective cancer treatment

Hyejin Kim, Hanjae Pyo, Hyeonsoo Kim, Hyun Wook Kang

Proceedings Volume 11919, 1191903 (2021) https://doi.org/10.1117/12.2614305

KEYWORDS: Tumors, Cancer, Laser irradiation, Photothermal effect, Oncology, Laser therapeutics, In vivo imaging, Temperature metrology, Tissue optics, Thermography

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Proceedings Article | 7 December 2021 Paper

Quantitative evaluations on EUS-guided laser ablation in ex-vivo and in-vivo porcine pancreas

Van Gia Truong, Jin-Seok Park, Van Nam Tran, Hyun Wook Kang

Proceedings Volume 11919, 1191908 (2021) https://doi.org/10.1117/12.2614455

KEYWORDS: Tissues, Laser ablation, In vivo imaging, Laser tissue interaction, Tumors, Safety, Pancreas, Nd:YAG lasers, Injuries, Ultrasonography

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Proceedings Article | 7 December 2021 Paper

A real-time evaluation of microfluidic-assisted laser treatment of poly-microbial biofilms

Van Nam Tran, Fazlurrahman Khan, Won Han, Van Gia Truong, Young Mog Kim, Joong Ho Shin, Hyun Wook Kang

Proceedings Volume 11919, 119192G (2021) https://doi.org/10.1117/12.2615059

KEYWORDS: Microfluidics, Bacteria, Laser therapeutics, Visualization, Systems modeling, Process modeling, Modulation, Microscopes, Medicine, Medical research

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Proceedings Article | 9 March 2021 Presentation

Stone ablation rates of a concept 100W pulse-modulated Holmium:YAG laser

Thomas Hasenberg, Bingyuan Yang, Ben Turney, Isha Parab, Jasmine Cancino, Sanwei Liu, Dongyul Chai, Aditi Ray, Tim Harrah, Hyun Kang

Proceedings Volume 11619, 1161907 (2021) https://doi.org/10.1117/12.2579016

KEYWORDS: Laser ablation, Prototyping, Fiber lasers, Surgery, Renal calculi, Pulsed laser operation, Laser vision correction, Laser therapeutics, Holmium

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Proceedings Article | 5 March 2021 Presentation

Welcome and Introduction to SPIE Conference 11619

Hyun Wook Kang, Ronald Sroka

Proceedings Volume 11619, 1161902 (2021) https://doi.org/10.1117/12.2592878

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Proceedings Article | 5 March 2021 Presentation

Effect of holmium:YAG laser pulse modulation on lithotripsy particle size: a bench study

Sanwei Liu, Aditi Ray, James Zhang, Dongyul Chai, Jason Xuan, Steven Peng, Tim Harrah, Bingyuan Yang, Ben Turney, Hyun Kang, Thomas Hasenberg

Proceedings Volume 11619, 1161909 (2021) https://doi.org/10.1117/12.2578831

KEYWORDS: Particles, Pulsed laser operation, Modulation, Laser therapeutics, YAG lasers, Rutherfordium, Laser applications, Laser ablation, Holmium, Fiber lasers

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Proceedings Article | 5 March 2021 Presentation

Stone retropulsion rates of a 100W pulse-modulated Holmium:YAG laser

Thomas Hasenberg, Sanwei Liu, Longquan Chen, Isha Parab, Jasmine Cancino, Aditi Ray, Jian James Zhang, Tim Harrah, Bingyuan Yang, Ben Turney, Hyun Wook Kang

Proceedings Volume 11619, 116190A (2021) https://doi.org/10.1117/12.2578996

KEYWORDS: Laser lithotripsy, Laser therapeutics, Pulsed laser operation, Prototyping, Laser ablation, Thermography, Thermal effects, Physical phenomena, Modulation

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Proceedings Article | 6 March 2020 Presentation

Dynamic combination of chemical and laser lights for bacterial biofilm disinfection in flexible ureteroscope (Conference Presentation)

Van Nam Tran, Fazlurrahman Khan, Van Gia Truong, Young Mog Kim, Hyun Wook Kang

Proceedings Volume 11212, 112120I (2020) https://doi.org/10.1117/12.2542485

KEYWORDS: Chemical lasers, Bacteria, Cameras, Temperature metrology, Crystals, Biological research

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Proceedings Article | 26 February 2019 Paper

Phloroglucinol-assisted low-level laser therapy (LLLT) to prevent recurrence of urethral stricture

Yeachan Lee, Hyejin Kim, Hyun Wook Kang

Proceedings Volume 10852, 1085208 (2019) https://doi.org/10.1117/12.2507114

KEYWORDS: Laser therapeutics, Collagen, Confocal microscopy, Absorbance, Proteins, Wound healing, In vivo imaging, Statistical analysis, Inflammation, Shape memory alloys

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Proceedings Article | 26 February 2019 Presentation + Paper

Investigations on pulse-processing model for diffuser-assisted LITT on prostate cancer

Van Gia Truong, Van Nam Tran, Hyun Wook Kang

Proceedings Volume 10852, 1085204 (2019) https://doi.org/10.1117/12.2507164

KEYWORDS: Tissues, Tissue optics, Prostate cancer, Liver, Laser tissue interaction, Cancer, Continuous wave operation, Tumor growth modeling, Prostate, Oncology

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Proceedings Article | 26 February 2019 Paper

Bactericidal activity of biofilm in flexible cystoscope under combined exposure of glutaraldehyde, 808-nm, and 405-nm laser

Van Nam Tran, Periaswamy Sivagnanam Saravana, Van Gia Truong, Byung-Soo Chun, Hyun Wook Kang

Proceedings Volume 10852, 108520J (2019) https://doi.org/10.1117/12.2507107

KEYWORDS: Bacteria, Cystoscopy, Infrared cameras, Microorganisms, Digital cameras, Diagnostics and therapeutics

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Proceedings Article | 14 March 2018 Presentation

Laser-assisted decontamination of biofilm in flexible cystoscope (Conference Presentation)

Van Nam Tran, Chakradhar Dasagrandhi, Van Gia Truong, Young Mog Kim, Hyun Wook Kang

Proceedings Volume 10468, 1046802 (2018) https://doi.org/10.1117/12.2287644

KEYWORDS: Infrared radiation, Infrared lasers, Infrared cameras, Surgery, Laser systems engineering, Cameras, Bacteria, Liquids, Laser therapeutics

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SPIE Journal Paper | 16 June 2017

Second-order fiber interleaving filter based on polarization-diversified loop

Kyongsoo Park, Sungwook Choi, Seul-Lee Lee, Jun Hyeok Jeong, Sun Jae Jeong, Nouaze Joseph Christian, Min Seok Kim, Jihoon Kim, Hyun Wook Kang, Seung Yun Nam, Junghwan Oh, Yong Wook Lee

OE, Vol. 56, Issue 06, 066108, (June 2017) https://doi.org/10.1117/12.10.1117/1.OE.56.6.066108

KEYWORDS: Optical filters, Birefringence, Linear filtering, Polarization, Beam splitters, Switching, Modulators

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SPIE Journal Paper | 20 April 2017 Open Access

Real-time temperature monitoring with fiber Bragg grating sensor during diffuser-assisted laser-induced interstitial thermotherapy

Ngot Thi Pham, Seul Lee Lee, Suhyun Park, Yong Wook Lee, Hyun Wook Kang

JBO, Vol. 22, Issue 04, 045008, (April 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.4.045008

KEYWORDS: Fiber Bragg gratings, Tissues, Temperature metrology, Diffusers, Laser tissue interaction, Liver, Sensors, Fiber lasers, Natural surfaces, Tissue optics

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Proceedings Article | 19 April 2017 Presentation

Quantitative comparison between radial and cylindrically diffusing fibers for photothermal treatment of varicose vein disease (Conference Presentation)

Gia Truong Van, Hyun Wook Kang

Proceedings Volume 10042, 100420G (2017) https://doi.org/10.1117/12.2250754

KEYWORDS: Veins, Optical fibers, Temperature metrology, Laser therapeutics, Combustion, Laser systems engineering, Laser tissue interaction, Thermal effects, Optical components, In vivo imaging

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Proceedings Article | 19 April 2017 Presentation

Temperature monitoring with FBG sensor during diffuser-assisted laser-induced interstitial thermotherapy (Conference Presentation)

Ngot Pham, Seul Lee Lee, Yong Wook Lee, Hyun Wook Kang

Proceedings Volume 10038, 100380B (2017) https://doi.org/10.1117/12.2251369

KEYWORDS: Technetium, Laser therapeutics, Fiber Bragg gratings, Sensors, Tissues, Temperature sensors, Temperature metrology, Heat therapy, Diffusers, Electromagnetic interference

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Temperature variations are often monitored by using sensors operating at the site of treatment during Laser-induced Interstitial Thermotherapy (LITT). Currently, temperature measurements during LITT have been performed with thermocouples (TCs). However, TCs could directly absorb laser light and lead to self-heating (resulting in an over-estimation). Fiber Bragg grating (FBG) sensors can instead overcome this limitation of the TCs due to its insensitivity to electromagnetic interference. The aim of the current study was to quantitatively evaluate the FBG temperature sensor with a K-type thermocouple to real-time monitor temperature increase in ex vivo tissue during diffuser-assisted LITT. A 4-W 980-nm laser was employed to deliver optical energy in continuous mode through a 600-µm core-diameter diffusing applicator. A goniometric measurement validated the uniform light distribution in polar and longitudinal directions. The FBG sensor showed a linear relationship (R2 = 0.995) between wavelength shift and temperature change in air and tissue along with a sensitivity of ~ 0.0114 nm/˚C. Regardless of sensor type, the measured temperature increased with irradiation time and applied power but decreased with increasing distance from the diffuser surface. The temperature elevation augmented the degree of thermal coagulation in the tissue during LITT (4.0±0.3-mm at 99˚C after 120-s). The temperature elevation augmented the degree of thermal coagulation in the tissue during LITT s irradiation). The FBG-integrated diffuser was able to monitor the interstitial temperature in tubular tissue (porcine urethra) real-time during laser treatment. However, the thermal coagulation thickness of the porcine urethra was measured to be 1.5 mm that was slightly thicker (~20%) than that of the bovine liver after 4-W 980-nm laser for 48 s. The FBG temperature sensor can be a feasible tool to real-time monitor the temporal development of the temperature during the diffuser-assisted LITT to treat urethral disease.

SPIE Journal Paper | 20 May 2016 Open Access

Ex vivo laser lipolysis assisted with radially diffusing optical applicator

Jieun Hwang, Nguyen Trung Hau, Sung Yeon Park, Yun-Hee Rhee, Jin-Chul Ahn, Hyun Wook Kang

JBO, Vol. 21, Issue 05, 058001, (May 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.5.058001

KEYWORDS: Tissues, Laser tissue interaction, Tissue optics, Diffusers, Fiber lasers, Biomedical optics, Ocean optics, Thermography, Natural surfaces, Microscopes

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Proceedings Article | 27 April 2016 Presentation

Application of novel optical diffuser for urethral stricture treatment (Conference Presentation)

Trung Hau Nguyen, Yun-Hee Rhee, Jin-Chul Ahn, Hyun Wook Kang

Proceedings Volume 9689, 96891H (2016) https://doi.org/10.1117/12.2212217

KEYWORDS: Tissues, Diffusers, Tissue optics, Optical fibers, Laser therapeutics, Laser tissue interaction, Optical fabrication, In vitro testing, Liver, Energy efficiency

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Optical fibers have frequently been used for photothermal laser therapy due to its efficiency to deliver laser energy directly to tissue. The aim of the current study was to develop a diffusing optical fiber to achieve radially uniform light irradiation for endoscopically treating urethral stricture. The optical diffuser was fabricated by micro-machining helical patterns on the fiber surface using CO2 laser light at 5 W. Visible light emission (632 nm) and spatial emissions (including polar, azimuthal, and longitudinal emissions) of the fiber tip were evaluated to validate the performance of the fabricated diffuser. Prior to tissue tests, numerical simulation on heat distribution was developed to estimate the degree of tissue coagulation depth during interstitial coagulation. Due to a high absorption coefficient by tissue water, 1470 nm laser was used for photothermal therapy treatment of urethral stricture to obtain a more precise depth profile. For in vitro tissue tests, porcine liver tissue was irradiated with three different power levels (3, 6, and 9 W) at various irradiation times. Porcine urethral tissue was also tested with the diffuser for 10 sec at 6 W to validate the feasibility of circumferential photothermal treatment. The treated tissue was stained with hematoxylin and eosin (H and E) and then imaged with an optical transmission microscope. The spatial emission characteristics of the diffusing optical fiber presented an almost uniform power distribution along the diffuser tip (less than 10% deviation) and around its circumference (less than 5% deviation). The peak temperature in simulation model at the tissue interface between the glass-cap and the tissue was 373 K that was higher than that at the distal end. The tissue tests showed that higher power levels resulted in lower coagulation thresholds (e.g., 1 sec at 9 W vs 8 sec at 3 W). Furthermore, the coagulation depth was approximately 20% thinner than the simulation results (p<0.001). The extent of coagulation thickness in urethral tissue was measured to be 1.3±0.2 mm, which was slightly thicker (18%) than the liver testing (1.1±0.1 mm) under the same conditions (p < 0.001). The proposed optical diffuser may be a feasible tool to treat the urethral stricture in a uniform manner.

Proceedings Article | 27 April 2016 Presentation

Feasibility of laser-integrated high intensity focused ultrasound (HIFU) treatment for bladder tumors: in vitro study (Conference Presentation)

Van Phuc Nguyen, Suhyun Park, Junghwan Oh, Hyun Wook Kang

Proceedings Volume 9689, 96891F (2016) https://doi.org/10.1117/12.2212201

KEYWORDS: Tumors, Ultrasonography, Bladder, In vitro testing, Laser therapeutics, Biomedical optics, Thermal effects, Chemical elements, Transducers, Acoustics

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SPIE Journal Paper | 10 December 2015 Open Access

Water content contribution in calculus phantom ablation during Q-switched Tm:YAG laser lithotripsy

Jian Zhang, Danop Rajabhandharaks, Jason Rongwei Xuan, Hui Wang, Ray W. Chia, Thomas Hasenberg, Hyun Wook Kang

JBO, Vol. 20, Issue 12, 128001, (December 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.12.128001

KEYWORDS: Calculus, Laser ablation, Pulsed laser operation, Q switched lasers, Laser lithotripsy, Laser therapeutics, Absorption, Fiber lasers, Cements, Calculi

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Proceedings Article | 26 February 2015 Paper

Photoactive dye enhanced tissue ablation for endoscopic laser prostatectomy

Minwoo Ahn, Trung Hau Nguyen, Van Phuc Nguyen, Junghwan Oh, Hyun Wook Kang

Proceedings Volume 9303, 93031D (2015) https://doi.org/10.1117/12.2077096

KEYWORDS: Laser ablation, Laser tissue interaction, Tissue optics, Tissues, Absorption, Prostate, Absorbance, Endoscopy, Laser therapeutics, Natural surfaces

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SPIE Journal Paper | 29 October 2014 Open Access

Feasibility study on photoacoustic guidance for high-intensity focused ultrasound-induced hemostasis

Van Phuc Nguyen, Jeehyun Kim, Kang-lyeol Ha, Junghwan Oh, Hyun Wook Kang

JBO, Vol. 19, Issue 10, 105010, (October 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.10.105010

KEYWORDS: Acoustics, Arteries, Tissues, Blood, Transducers, Blood vessels, Ultrasonography, Photoacoustic spectroscopy, Tissue optics, Absorption

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Proceedings Article | 4 March 2014 Paper

Blood coagulation using High Intensity Focused Ultrasound (HIFU)

Phuc Nguyen, Junghwan Oh, Hyun Wook Kang

Proceedings Volume 8926, 89261A (2014) https://doi.org/10.1117/12.2037171

KEYWORDS: Arteries, Blood, Acoustics, Transducers, Tissues, Ultrasonography, Photoacoustic spectroscopy, Blood vessels, Absorption, Injuries

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Proceedings Article | 8 March 2013 Paper

Dependence of water content in calculus phantom during Q-switched Tm:YAG laser lithotripsy

Danop Rajabhandharaks, Jian Zhang, Hui Wang, Jason Xuan, Ray W. Chia, Tom Hasenberg, Hyun Wook Kang

Proceedings Volume 8565, 856519 (2013) https://doi.org/10.1117/12.2004830

KEYWORDS: Calculus, Laser ablation, Q switched lasers, Laser lithotripsy, Pulsed laser operation, Glasses, Absorption, Cements, Calculi, Fiber lasers

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SPIE Journal Paper | 15 November 2012 Open Access

Enhanced photocoagulation with catheter-based diffusing optical device

Hyun Wook Kang, Jeehyun Kim, Junghwan Oh

JBO, Vol. 17, Issue 11, 118001, (November 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.11.118001

KEYWORDS: Tissue optics, Uterus, Tissues, Laser coagulation, Optical components, Diffusers, In vivo imaging, Laser tissue interaction, Natural surfaces, Prototyping

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Proceedings Article | 18 February 2011 Paper

MoXy fiber with active cooling cap for bovine prostate vaporization with high power 200W 532 nm laser

Steven Peng, Hyun Wook Kang, Homa Pirzadeh, Douglas Stinson

Proceedings Volume 7883, 78831D (2011) https://doi.org/10.1117/12.875195

KEYWORDS: Tissues, Prostate, Fiber lasers, Laser ablation, In vitro testing, Metals, Laser systems engineering, Optical fibers, Energy efficiency, Transmittance

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Proceedings Article | 18 February 2011 Paper

Interaction between high power 532nm laser and prostatic tissue: in vitro evaluation for laser prostatectomy

Hyun Wook Kang, Yihlih Steven Peng, Douglas Stinson

Proceedings Volume 7883, 78831E (2011) https://doi.org/10.1117/12.875517

KEYWORDS: Tissues, Laser ablation, Laser tissue interaction, Prostate, In vitro testing, Natural surfaces, Picosecond phenomena, High power lasers, Laser development, Laser systems engineering

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Proceedings Article | 18 February 2011 Paper

In vitro assessment of fiber sweeping speed during Q-switched 532-nm laser tissue ablation

Danop Rajabhandharaks, Hyun Wook Kang, Woo Jin Ko, Douglas Stinson, Benjamin Choi

Proceedings Volume 7883, 78831K (2011) https://doi.org/10.1117/12.879275

KEYWORDS: Tissues, Laser ablation, Laser tissue interaction, Fiber lasers, Q switched lasers, Prostate, In vitro testing, Kidney, Tissue optics, Natural surfaces

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Proceedings Article | 18 February 2011 Paper

Interaction between high power 532nm laser and prostatic tissue: in vivo evaluation for laser prostatectomy

Reza Malek, Hyun Wook Kang, Steven Yihlih Peng, Douglas Stinson, Michael Beck, Ed Koullick

Proceedings Volume 7883, 78831F (2011) https://doi.org/10.1117/12.875535

KEYWORDS: Prostate, Laser tissue interaction, Tissues, Laser ablation, Fiber lasers, Collagen, High power lasers, In vivo imaging, Laser development, Natural surfaces

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Proceedings Article | 18 February 2011 Paper

In vitro assessment of fiber sweeping angle during Q-switched 532-nm laser tissue ablation

Danop Rajabhandharaks, Hyun Wook Kang, Woo Jin Ko, Douglas Stinson, Benjamin Choi

Proceedings Volume 7883, 78831J (2011) https://doi.org/10.1117/12.879271

KEYWORDS: Tissues, Laser ablation, Prostate, Laser tissue interaction, Q switched lasers, Natural surfaces, In vitro testing, Kidney, Aluminum, Fiber lasers

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Proceedings Article | 2 March 2010 Paper

Investigation of wavelength-dependent tissue ablation: visible (lambda= 532 nm) vs IR (lambda= 2.01 µm)

Hyun Wook Kang, Yihlih Steven Peng

Proceedings Volume 7548, 75481B (2010) https://doi.org/10.1117/12.841045

KEYWORDS: Tissues, Laser ablation, Laser tissue interaction, Visible radiation, Natural surfaces, Prostate, Continuous wave operation, Tissue optics, Infrared lasers, Kidney

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Proceedings Article | 8 February 2008 Paper

Comparative study on laser tissue ablation between PV and HPS lasers

Hyun Wook Kang, David Jebens, Gerald Mitchell, Ed Koullick

Proceedings Volume 6842, 68420X (2008) https://doi.org/10.1117/12.760075

KEYWORDS: Laser ablation, Photovoltaics, Laser tissue interaction, Tissues, Laser systems engineering, Fiber lasers, Prostate, Laser therapeutics, Tissue optics, Collimation

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Proceedings Article | 8 March 2007 Paper

Effect of water spray during laser ablation on dental hard tissue

Hyun Wook Kang, Ioana Rizoiu, A. Welch

Proceedings Volume 6425, 64250M (2007) https://doi.org/10.1117/12.702034

KEYWORDS: Laser ablation, Acoustics, Pulsed laser operation, Optical coherence tomography, Laser tissue interaction, Tissues, Laser dentistry, Image processing, Natural surfaces, Fiber lasers

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Proceedings Article | 22 February 2006 Paper

Investigation of stone retropulsion as a function of Ho:YAG laser pulse duration

Hyun Wook Kang, Ho Lee, Jason Petersen, J. Teichman, A. Welch

Proceedings Volume 6078, 607815 (2006) https://doi.org/10.1117/12.646513

KEYWORDS: Optical fibers, Pulsed laser operation, Laser ablation, Calculus, Laser lithotripsy, Optical coherence tomography, Distance measurement, High speed cameras, Calculi, Interfaces

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Proceedings Article | 25 April 2005 Paper

Comparison of urinary calculus fragmentation during Ho:YAG and Er:YAG lithotripsy

Hyun Wook Kang, Ho Lee, Joel Teichman, A. Welch

Proceedings Volume 5686, (2005) https://doi.org/10.1117/12.589455

KEYWORDS: Er:YAG lasers, Laser ablation, Calculus, Pulsed laser operation, Calculi, Absorption, Laser drilling, Energy efficiency, Laser lithotripsy, Laser therapeutics

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Showing 5 of 59 publications

Proceedings Volume Editor (13)

SPIE Conference Volume | 22 March 2024

Advanced Photonics in Urology 2024

SPIE Conference Volume | 14 April 2023

Advanced Photonics in Urology 2023

SPIE Conference Volume | 22 April 2021

Advanced Photonics in Urology

SPIE Conference Volume | 4 March 2020

Therapeutics and Diagnostics in Urology 2020

SPIE Conference Volume | 7 June 2019

Therapeutics and Diagnostics in Urology 2019

Showing 5 of 13 publications

Conference Committee Involvement (19)

Advanced Photonics in Urology 2025

25 January 2025 | San Francisco, California, United States

Advanced Photonics in Urology 2024

27 January 2024 | San Francisco, California, United States

SPIE Advanced Biophotonics Conference (SPIE ABC 2023)

1 November 2023 | Jeju, Korea, Republic of

Advanced Photonics in Urology 2023

28 January 2023 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXXIII and Advanced Photonics in Urology

22 January 2022 | San Francisco, California, United States

SPIE Advanced Biophotonics Conference (SPIE ABC 2021)

4 November 2021 | Busan, Republic of Korea

Advanced Photonics in Urology

6 March 2021 | Online Only, California, United States

Therapeutics and Diagnostics in Urology 2020

1 February 2020 | San Francisco, California, United States

Translation of Lasers and Biophotonics Technologies and Procedures: Toward the Clinic

23 June 2019 | Munich, Germany

Therapeutics and Diagnostics in Urology 2019

2 February 2019 | San Francisco, California, United States

Therapeutics and Diagnostics in Urology 2018

27 January 2018 | San Francisco, California, United States

Therapeutics and Diagnostics in Urology

28 January 2017 | San Francisco, California, United States

Therapeutics and Diagnostics in Urology

13 February 2016 | San Francisco, California, United States

Therapeutics and Diagnostics in Urology

7 February 2015 | San Francisco, California, United States

Therapeutics and Diagnostics in Urology

1 February 2014 | San Francisco, California, United States

Therapeutics and Diagnostics in Urology: Lasers, Robotics, Minimally Invasive, and Advanced Biomedical Devices

2 February 2013 | San Francisco, California, United States

Therapeutics and Diagnostics in Urology: Lasers, Robotics, Minimally Invasive, and Advanced Biomedical Devices

21 January 2012 | San Francisco, California, United States

Urology: Diagnostics, Therapeutics, Robotics, Minimally Invasive, and Photodynamic Therapy

22 January 2011 | San Francisco, California, United States

Urology: Diagnostics, Therapeutics, Robotics, Minimally Invasive, and Photodynamic Therapy

23 January 2010 | San Francisco, California, United States

Showing 5 of 19 Conference Committees

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