Dr. Randolph D. Glickman Profile

Dr. Randolph D. Glickman

Adjunct Professor (Retired)

SPIE Involvement:

Conference Program Committee | Author

Publications (61)

Proceedings Article | 9 February 2017 Presentation + Paper

Identification and localization of trauma-related biomarkers using matrix assisted laser desorption/ionization imaging mass spectrometry

Kirstin Jones, Matthew Reilly, Randolph Glickman

Proceedings Volume 10046, 100460G (2017) https://doi.org/10.1117/12.2256647

KEYWORDS: Proteins, Tissues, Mass spectrometry, Optic nerve, Injuries, Retina, Robotic systems, Eye, Biological research

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Proceedings Article | 15 March 2016 Presentation + Paper

All-optical optoacoustic microscopy system based on probe beam deflection technique

Saher Maswadi, Dmitri Tsyboulskic, Caleb Roth, Randolph Glickman, Hope Beier, Alexander Oraevsky, Bennett Ibey

Proceedings Volume 9708, 970818 (2016) https://doi.org/10.1117/12.2217690

KEYWORDS: Laser beam diagnostics, Imaging systems, Microscopy, Acoustics, Adaptive optics, Sensors, Signal detection, Microscopes, Objectives, Image sensors, Tissue optics, Image resolution, Photodiodes

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Proceedings Article | 9 March 2016 Presentation + Paper

Short infrared (IR) laser pulses can induce nanoporation

Caleb Roth, Ronald Barnes, Bennett Ibey, Randolph Glickman, Hope Beier

Proceedings Volume 9690, 96901L (2016) https://doi.org/10.1117/12.2214892

KEYWORDS: Action potentials, Infrared lasers, Thallium, Infrared radiation, Ions, Nerve, Neurophotonics, Luminescence, Analytical research, Statistical analysis

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Proceedings Article | 7 March 2016 Paper

Protein-protein binding before and after photo-modification of albumin

Sarah Rozinek, Randolph Glickman, Robert Thomas, Lorenzo Brancaleon

Proceedings Volume 9706, 97061J (2016) https://doi.org/10.1117/12.2213632

KEYWORDS: Proteins, Chromatography, Visible radiation, Liquids, Luminescence, Solids, Biomedical optics, Health sciences, Photochemical interactions, Receptors

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Proceedings Article | 7 March 2016 Presentation + Paper

Conductivity affects nanosecond electrical pulse induced pressure transient formation

Caleb Roth, Ronald Barnes, Bennett Ibey, Hope Beier, Randolph Glickman

Proceedings Volume 9706, 97060V (2016) https://doi.org/10.1117/12.2214896

KEYWORDS: Acoustics, Laser beam diagnostics, Electrodes, Calcium, Water, Electrostriction, Medicine, Health sciences, Analytical research, Roads, Tissue optics

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Proceedings Article | 12 March 2015 Paper

Cells exposed to nanosecond electrical pulses exhibit biomarkers of mechanical stress

Caleb Roth, Ronald Barnes, Bennett Ibey, Hope Beier, Erick Moen, Randolph Glickman

Proceedings Volume 9326, 932612 (2015) https://doi.org/10.1117/12.2080219

KEYWORDS: Plasma, Receptors, Proteins, Genetics, Acoustics, Biological research, Ultrasonics, Absorbance, Analytical research, Calcium

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Proceedings Article | 13 March 2014 Paper

Characterization of acoustic shockwaves generated by exposure to nanosecond electrical pulses

Caleb Roth, Saher Maswadi, Bennett Ibey, Hope Beier, Randolph Glickman

Proceedings Volume 8941, 89411O (2014) https://doi.org/10.1117/12.2042184

KEYWORDS: Acoustics, Electrodes, Laser beam diagnostics, Plasma, Tungsten, Sensors, Metals, Cavitation, Silver, Platinum

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Proceedings Article | 3 March 2014 Paper

Optoacoustic microscopy using laser beam deflection technique

E. Khachatryan, S. Maswadi, D. Tsyboulski, E. Barnes, D. Sardar, A. Oraevsky, K. Nash, R. Glickman

Proceedings Volume 8943, 89432T (2014) https://doi.org/10.1117/12.2040718

KEYWORDS: Laser beam diagnostics, Tissue optics, Ultrasonography, Acoustics, Microscopy, Objectives, Image resolution, Tissues, Transducers, Nanoparticles

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Optoacoustic microscopy (OAM) is an emerging technology combining the beneficial features of optical contrast and ultrasound resolution, to form a hybrid imaging technique capable of multi-scale, high-contrast and high-resolution imaging through optically scattering biological tissues. In the past 15 years, two system modifications have been developed for optoacoustic / photoacoustic microscopy: acoustic-resolution AR-OAM and optical-resolution OR-OAM. Typically, acoustic resolution systems can image deeper tissues structures, however, with resolution at least an order of magnitude worse than the systems of optical-resolution. It would be attractive for variety of biomedical applications to attain high (submicron) resolution at a depth exceeding the present limit of the optical resolution optoacoustic microscopy. Here we introduce a novel, all-optical method for OAM, in which not only thermal energy deposition, but also optoacoustic signal detection is achieved optically. In our design the probe laser beam was used as an ultrawide-band ultrasonic transducer. In this method the acoustic pressure wave amplitude is proportional to the angle of deflection of the probing CW laser beam incident on a balanced dual photodiode. Such laser beam deflection (LBD) method overcomes the limitations of conventional piezoelectric ultrasound transducers and optical interferometers. LBD method allows one to use high numerical aperture objectives for better focusing, avoid distortions associated with the system elements that separate optical and acoustic paths, and provides better sensitivity than any optical interferometer. It also provides a non-contact method that is insensitive to optical and acoustic artifacts typical of backward mode of optoacoustic imaging. The LBD sensitivity depends on a large number of system parameters such as probe beam power, spot size, interaction length, optical refraction index of the coupling medium, laser wavelength, photodiode sensitivity, proximity to the optoacoustic source, and thus, can be optimized. The basic setup of OR-LBD-OAM shows high sensitivity competitive with commercial ultrasonic transducers. We report first images of biological cells and tissues obtained using this technique.

Proceedings Article | 15 February 2013 Paper

Ursolic acid mediates photosensitization by initiating mitochondrial-dependent apoptosis

Yuan-Hao Lee, Exing Wang, Neeru Kumar, Randolph Glickman

Proceedings Volume 8579, 85790F (2013) https://doi.org/10.1117/12.2000225

KEYWORDS: Cell death, Proteins, Control systems, Tumors, Modulation, Mode conditioning cables, Ultraviolet radiation, Oxygen, Modulators, Oxidation

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Proceedings Article | 15 February 2013 Paper

Detection of oxidative stress biomarker-induced assembly of gold nanoparticles in retinal pigment epithelial cells

Z. Yasmin, Y. Lee, S. Maswadi, R. Glickman, K. Nash

Proceedings Volume 8579, 85790E (2013) https://doi.org/10.1117/12.2003156

KEYWORDS: Gold, Nanoparticles, Absorption, Photoacoustic spectroscopy, Surface plasmons, Sensors, Biosensors, Scanning electron microscopy, Nanolithography, Biomedical optics

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Proceedings Article | 9 February 2012 Paper

Protection and sensitization of normal and malignant cells by a naturally occurring compound in a model of photochemical damage

Yuan-Hao Lee, Neeru Kumar, Randolph Glickman

Proceedings Volume 8221, 82211M (2012) https://doi.org/10.1117/12.910359

KEYWORDS: Cell death, Proteins, Skin, Melanoma, Tumors, Radiation effects, Luminescence, Modulation, Ultraviolet radiation, Oxidation

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Proceedings Article | 28 February 2011 Paper

Optoacoustic sensor for nanoparticle linked immunosorbent assay (NanoLISA)

André Conjusteau, Anton Liopo, Dmitri Tsyboulski, Sergey Ermilov, William Elliott, Norman Barsalou, Saher Maswadi, Randolph Glickman, Alexander Oraevsky

Proceedings Volume 7899, 789910 (2011) https://doi.org/10.1117/12.879401

KEYWORDS: Gold, Sensors, Nanoparticles, Biosensors, Target detection, Ferroelectric polymers, Pulsed laser operation, Acoustics, Signal to noise ratio, Nanorods

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Proceedings Article | 23 February 2011 Paper

Identification of radiolucent foreign bodies in tissue using optoacoustic spectroscopic imaging

Leland Page, Saher Maswadi, Randolph Glickman

Proceedings Volume 7899, 78993I (2011) https://doi.org/10.1117/12.875403

KEYWORDS: Absorption, Spectroscopy, Tissue optics, Laser beam diagnostics, Imaging spectroscopy, Optical parametric oscillators, Visible radiation, Absorption spectroscopy, Acoustics, Tissues

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Proceedings Article | 18 February 2011 Paper

Nano-LISA for in vitro diagnostic applications

Saher Maswadi, Randolph Glickman, Rowe Elliott, Norman Barsalou

Proceedings Volume 7899, 78991O (2011) https://doi.org/10.1117/12.874922

KEYWORDS: Gold, Laser beam diagnostics, Silver, In vitro testing, Target detection, Sensors, Signal detection, LabVIEW, Absorption, Nanorods

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Proceedings Article | 12 March 2010 Paper

Optoacoustic spectroscopic imaging of radiolucent foreign bodies

Leland Page, Saher Maswadi, Randolph Glickman

Proceedings Volume 7629, 76290E (2010) https://doi.org/10.1117/12.844468

KEYWORDS: Spectroscopy, Absorption, Imaging spectroscopy, Imaging systems, Laser beam diagnostics, Optical parametric oscillators, Tissues, Ultrasonography, Glasses, Visible radiation

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SPIE Journal Paper | 1 March 2010 Open Access

Femtosecond laser lithotripsy: feasibility and ablation mechanism

Jinze Qiu, Joel Teichman, Tianyi Wang, Joseph Neev, Randolph Glickman, Kin Foong Chan, Thomas Milner

JBO, Vol. 15, Issue 02, 028001, (March 2010) https://doi.org/10.1117/12.10.1117/1.3368998

KEYWORDS: Laser ablation, Femtosecond phenomena, Calculi, Plasma, Calculus, Laser lithotripsy, Pulsed laser operation, Laser therapeutics, Ferroelectric polymers, Photography

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Proceedings Article | 25 February 2009 Paper

Detection of gold-nanorod targeted pathogens using optical and piezoelectric optoacoustic sensors: comparative study

André Conjusteau, Saher Maswadi, Sergey Ermilov, Hans-Peter Brecht, Norman Barsalou, Randolph Glickman, Alexander Oraevsky

Proceedings Volume 7177, 71771P (2009) https://doi.org/10.1117/12.813434

KEYWORDS: Transducers, Acoustics, Sensors, Laser beam diagnostics, Gold, Signal detection, Signal generators, Target detection, Pathogens, Nanorods

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Proceedings Article | 12 February 2009 Paper

Optoacoustic detection of viral antigens using targeted gold nanorods

Saher Maswadi, Lee Woodward, Randolph Glickman, Norman Barsalou

Proceedings Volume 7177, 71771Q (2009) https://doi.org/10.1117/12.809186

KEYWORDS: Gold, RGB color model, Silver, Target detection, Signal detection, Laser spectroscopy, Absorption, Laser beam diagnostics, Spectroscopy, Nanorods

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Proceedings Article | 12 February 2009 Paper

Optoacoustic imaging: application to the detection of foreign bodies

Leland Page, Saher Maswadi, Randolph Glickman, Norman Barsalou, Ron Branstetter, Scott Thompson

Proceedings Volume 7177, 71770X (2009) https://doi.org/10.1117/12.809516

KEYWORDS: Ultrasonography, Laser beam diagnostics, Acoustics, Imaging systems, Tissues, Transducers, Magnetic resonance imaging, Optical parametric oscillators, Image resolution, X-ray computed tomography

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Proceedings Article | 28 February 2008 Paper

Optoacoustic sensing of ocular bacterial antigen using targeted gold nanorods

Saher Maswadi, Leland Page, Lee Woodward, Randolph Glickman, Norman Barsalou

Proceedings Volume 6856, 685615 (2008) https://doi.org/10.1117/12.766512

KEYWORDS: Silver, Gold, Optical parametric oscillators, Target detection, Absorption, Spectroscopy, Signal detection, Laser spectroscopy, Laser beam diagnostics, Nanorods

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Proceedings Article | 21 February 2007 Paper

Functional and cellular responses to laser injury in the rat snake retina

Randolph Glickman, W. Rowe Elliott, Neeru Kumar

Proceedings Volume 6435, 643511 (2007) https://doi.org/10.1117/12.698801

KEYWORDS: Retina, Injuries, Second-harmonic generation, Eye, Cell death, Visualization, Laser tissue interaction, Spatial frequencies, Eyeglasses, Modulation

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Proceedings Article | 13 February 2007 Paper

Investigational detection of pharmacological agents in the eye using photoacoustic spectroscopy

Saher Maswadi, Randolph Glickman, Norman Barslou, Rowe Elliott

Proceedings Volume 6437, 643706 (2007) https://doi.org/10.1117/12.699094

KEYWORDS: Photoacoustic spectroscopy, Eye, Tissue optics, Absorption, Optical parametric oscillators, Pulsed laser operation, In vivo imaging, Laser tissue interaction, Tunable lasers, Retina

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Proceedings Article | 7 March 2006 Paper

Investigation of photoacoustic spectroscopy for biomolecular detection

Saher Maswadi, Randolph Glickman, Norman Barsalou, Rowe Elliott

Proceedings Volume 6138, 61380V (2006) https://doi.org/10.1117/12.674408

KEYWORDS: Photoacoustic spectroscopy, Eye, Tissue optics, In vivo imaging, Absorption, Laser beam diagnostics, Pulsed laser operation, Retina, Continuous wave operation, Q switched lasers

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Proceedings Article | 22 February 2006 Paper

A comparison of single use and reusable small core sized holmium:YAG laser fibers: Is there a difference in the risk of fiber failure?

Bodo Knudsen, Randolph Glickman, Joel Teichman

Proceedings Volume 6078, 607813 (2006) https://doi.org/10.1117/12.646864

KEYWORDS: Optical fibers, Fiber lasers, Waveguides, Manufacturing, Shape memory alloys, Connectors, Laser lithotripsy, Endoscopes, Holmium, Singular optics

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Proceedings Article | 15 April 2005 Paper

Intracellular signaling mechanisms responsive to laser-induced photochemical and thermal stress

Randolph Glickman, Mohan Natarajan, Benjamin Rockwell, Michael Denton, Saher Maswadi, Neeru Kumar, Francis Nieves-Roldan

Proceedings Volume 5695, (2005) https://doi.org/10.1117/12.584135

KEYWORDS: Continuous wave operation, Proteins, Cell death, Laser tissue interaction, Injuries, Ultraviolet radiation, Oxygen, Receptors, Laser therapeutics, Oxidation

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SPIE Journal Paper | 1 July 2004 Open Access

Temperature mapping of laser-induced hyperthermia in an ocular phantom using magnetic resonance thermography

Saher Maswadi, Stephen Dodd, Jia Hong Gao, Randolph Glickman

JBO, Vol. 9, Issue 04, (July 2004) https://doi.org/10.1117/12.10.1117/1.1751399

KEYWORDS: Temperature metrology, Magnetism, Thermography, Thermal modeling, Eye, Magnetic resonance imaging, Spatial resolution, Laser tissue interaction, Laser therapeutics, Laser scattering

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Proceedings Article | 1 July 2004 Paper

Photo-oxidation from mode-locked laser exposure to hTERT-RPE1 cells

Michael Denton, Debbie Eikum, Gary Noojin, David Stolarski, Randolph Glickman, Benjamin Rockwell

Proceedings Volume 5319, (2004) https://doi.org/10.1117/12.529355

KEYWORDS: Mode locking, Luminescence, Continuous wave operation, Near infrared, Laser damage threshold, Microscopy, Microscopes, Fluorescence spectroscopy, Target detection, Oxidation

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Proceedings Article | 1 July 2004 Paper

Noninvasive thermography of laser-induced hyperthermia using magnetic resonance

Saher Maswadi, Randolph Glickman, Stephen Dodd, Jia Hong Gao

Proceedings Volume 5319, (2004) https://doi.org/10.1117/12.527809

KEYWORDS: Temperature metrology, Laser tissue interaction, Thermal modeling, Magnetic resonance imaging, Laser scattering, Laser therapeutics, Spatial resolution, Diffusion, Thermography, Magnetism

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Proceedings Article | 1 July 2004 Paper

Multiphoton absorption is probably not the primary threshold damage mechanism for femtosecond laser pulse exposures in the retinal pigment epithelium

Randolph Glickman, Thomas Johnson

Proceedings Volume 5319, (2004) https://doi.org/10.1117/12.527843

KEYWORDS: Photons, Absorption, Comets, Pulsed laser operation, Continuous wave operation, Ultrafast phenomena, Laser damage threshold, Luminescence, Near infrared

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Proceedings Article | 27 August 2003 Paper

Melanin and the cellular effects of ultrashort-pulse near-infrared laser radiation

Randolph Glickman, Neeru Kumar, Benjamin Rockwell, Gary Noojin, Michael Denton, David Stolarski

Proceedings Volume 4961, (2003) https://doi.org/10.1117/12.477653

KEYWORDS: Comets, Continuous wave operation, Near infrared, Pulsed laser operation, Ultrafast phenomena, Chromophores, Absorption, Control systems, Mode locking

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Proceedings Article | 14 July 2003 Paper

Composition of the excimer laser-induced plume produced during LASIK refractive surgery

Randolph Glickman, Yun Liu, George Mayo, Alan Baribeau, Tomy Starck, Tom Bankhead

Proceedings Volume 4951, (2003) https://doi.org/10.1117/12.477953

KEYWORDS: Optical filters, Laser vision correction, Excimer lasers, LASIK, Surgery, Laser therapeutics, Scanning electron microscopy, Molecules, Particles, Laser ablation

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Proceedings Article | 20 June 2003 Paper

Pigmentation in NIR laser tissue damage

Michael Denton, Debbie Eikum, Gary Noojin, David Stolarski, Robert Thomas, Randolph Glickman, Benjamin Rockwell

Proceedings Volume 4953, (2003) https://doi.org/10.1117/12.476898

KEYWORDS: Mode locking, Continuous wave operation, Laser tissue interaction, Near infrared, Laser damage threshold, Laser induced damage, Particles, Cell death, In vivo imaging, Absorption

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Proceedings Article | 20 June 2003 Paper

Nonlinear optical characterization of retinal molecules

Kristy Hayes, Robert Thomas, Jacob Stolarski, Benjamin Rockwell, David Stolarski, Michael Denton, Debbie Eikum, Gary Noojin, Randolph Glickman

Proceedings Volume 4953, (2003) https://doi.org/10.1117/12.476886

KEYWORDS: Absorption, Retina, Laser damage threshold, Transmittance, Ultrafast phenomena, Pulsed laser operation, Laser induced breakdown spectroscopy, Laser induced damage, Tissues, Molecules

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Proceedings Article | 27 June 2002 Paper

Hydrogen peroxide production in cultured RPE cells exposed to near-infrared lasers

Michael Denton, Debbie Eikum, David Stolarski, Gary Noojin, Robert Thomas, Randolph Glickman, Benjamin Rockwell

Proceedings Volume 4617, (2002) https://doi.org/10.1117/12.472518

KEYWORDS: Luminescence, Mode locking, Continuous wave operation, Hydrogen, Target detection, Near infrared, Absorption, Multiphoton fluorescence microscopy, Microscopy, Oxygen

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Proceedings Article | 27 June 2002 Paper

Cytotoxicity in cultured RPE: a comparative study between continuous-wave and mode-locked lasers

Michael Denton, Debbie Eikum, David Stolarski, Gary Noojin, Robert Thomas, Randolph Glickman, Benjamin Rockwell

Proceedings Volume 4617, (2002) https://doi.org/10.1117/12.472519

KEYWORDS: Continuous wave operation, Mode locking, Cell death, Luminescence, Laser safety, Near infrared, In vivo imaging, Retina, Visualization, Laser applications

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Proceedings Article | 27 June 2002 Paper

Evidence for excitation of fluorescence in RPE melanin by multiphoton absorption

Randolph Glickman, Benjamin Rockwell, Gary Noojin, David Stolarski, Michael Denton

Proceedings Volume 4617, (2002) https://doi.org/10.1117/12.472521

KEYWORDS: Luminescence, Absorption, Ultrafast phenomena, Continuous wave operation, Chromophores, Pulsed laser operation, Near infrared, Raman spectroscopy, Spectroscopy

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SPIE Journal Paper | 1 October 2001 Open Access

Optical characterization of melanin

Dhiraj Sardar, Michael Mayo, Randolph Glickman

JBO, Vol. 6, Issue 04, (October 2001) https://doi.org/10.1117/12.10.1117/1.1411978

KEYWORDS: Scattering, Absorption, Particles, Transmittance, Optical properties, Monte Carlo methods, Light scattering, Anisotropy, Integrating spheres, Optical testing

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Proceedings Article | 9 July 2001 Paper

Pulsewidth-dependent nature of laser-induced DNA damage in RPE cells

Rebecca Hall, Randolph Glickman, Benjamin Rockwell, Neeru Kumar, Gary Noojin

Proceedings Volume 4257, (2001) https://doi.org/10.1117/12.434700

KEYWORDS: Comets, Pulsed laser operation, Ultrafast phenomena, Mode locking, Continuous wave operation, Head, Absorption, Photons, Microscopes, Molecules

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Proceedings Article | 9 July 2001 Paper

Revisiting the internal absorption coefficient of the retinal pigment epithelium melanosome

Randolph Glickman, Steven Jacques, Rebecca Hall, Neeru Kumar

Proceedings Volume 4257, (2001) https://doi.org/10.1117/12.434697

KEYWORDS: Absorption, Laser damage threshold, Retina, Visualization, Skin, Optical properties, Tissues, Health sciences, Eye, Oxidation

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Proceedings Article | 4 May 2001 Paper

Physical and photochemical properties of ocular melanin

Randolph Glickman, James Gallas, Steven Jacques, Benjamin Rockwell, Dhiraj Sardar

Proceedings Volume 4241, (2001) https://doi.org/10.1117/12.431511

KEYWORDS: Particles, Absorption, Scattering, Light scattering, Visible radiation, Eye, Scanning tunneling microscopy, X-rays, Tissue optics, Retina

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Proceedings Article | 13 June 2000 Paper

Further characterization of photothermal breakdown products of uric acid stones following holmium:YAG laser lithotripsy

Randolph Glickman, Susan Weintraub, Neeru Kumar, Nicole Corbin, Omid Lesani, Joel Teichman

Proceedings Volume 3914, (2000) https://doi.org/10.1117/12.388040

KEYWORDS: Mass spectrometry, Absorption, Nd:YAG lasers, Ultraviolet radiation, Statistical analysis, Cyanide, Laser irradiation, Laser ablation, Chemical analysis, Calculi

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Proceedings Article | 13 June 2000 Paper

In-vitro Erbium:YAG laser lithotripsy

Kin Foong Chan, Gracie Vargas, Patricia Parker, Joel Teichman, Randolph Glickman, H. Stan McGuff, Ashley Welch

Proceedings Volume 3914, (2000) https://doi.org/10.1117/12.388046

KEYWORDS: Er:YAG lasers, Calculus, Acoustics, Sapphire, Laser lithotripsy, Plasma, Fiber lasers, Pulsed laser operation, Laser therapeutics, Laser energy

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Proceedings Article | 17 May 2000 Paper

Proteus mirabilis viability after lithotripsy of struvite calculi

Sabitha Prabakharan, Joel Teichman, Scott Spore, Edmund Sabanegh, Randolph Glickman, Robert McLean

Proceedings Volume 3907, (2000) https://doi.org/10.1117/12.386261

KEYWORDS: Calculi, Control systems, Bacteria, Dye lasers, Ultrasonics, Magnesium, Laser therapeutics, Acoustics, Information operations, Statistical analysis

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Proceedings Article | 17 September 1999 Paper

Photo-oxidative stress in the eye: role of retinal pigment epithelial pigments

Randolph Glickman, Alexander Dontsov, Michail Ostrovsky, Neeru Kumar, Meena Vendal, Mary Gonzales

Proceedings Volume 3863, (1999) https://doi.org/10.1117/12.364425

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Proceedings Article | 17 September 1999 Paper

Photothermal ablation is the primary mechanism in holmium:YAG laser lithotripsy of urinary calculi

Randolph Glickman, Joel Teichman, Nicole Corbin, George Vassar, Susan Weintraub, Kin Foong Chan, Ashley Welch

Proceedings Volume 3863, (1999) https://doi.org/10.1117/12.364416

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SPIE Journal Paper | 1 July 1999 Open Access

Activated rate processes and a specific biochemical mechanism for explaining delayed laser induced thermal damage to the retina

Bernard Gerstman, Randolph Glickman

JBO, Vol. 4, Issue 03, (July 1999) https://doi.org/10.1117/12.10.1117/1.429936

KEYWORDS: Proteins, Retina, Molecules, Thin film coatings, Laser induced damage, Argon ion lasers, Visible radiation, Pulsed laser operation, Thermal effects, Laser damage threshold

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Proceedings Article | 22 June 1999 Paper

Photothermal laser lithotripsy of uric acid calculi: clinical assessment of the effects of cyanide production

Joel Teichman, Paolo Champion, Randolph Glickman, Timothy Wollin, John Denstedt

Proceedings Volume 3590, (1999) https://doi.org/10.1117/12.350964

KEYWORDS: Cyanide, Calculi, Toxicity, Bladder, Calculus, Absorption, Cystoscopy, Laser lithotripsy, Mercury, Blood

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Proceedings Article | 14 June 1999 Paper

Chemical decomposition of urinary stones during holmium-laser lithotripsy: I. Lack of a photomechanical effect

Kin Foong Chan, George Vassar, T. Joshua Pfefer, Joel Teichman, Randolph Glickman, Susan Weintraub, Ashley Welch

Proceedings Volume 3601, (1999) https://doi.org/10.1117/12.350023

KEYWORDS: Holmium, Acoustics, Pulsed laser operation, Laser energy, Laser therapeutics, Laser lithotripsy, Photography, Cavitation, Calculus, Fiber lasers

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Proceedings Article | 14 June 1999 Paper

Intracellular photochemical reactions in the RPE cell exhibit a wavelength dependence that resembles the action spectrum of melanin

Randolph Glickman, Meena Vendal, Mary Ann Gonzalez, Neeru Kumar

Proceedings Volume 3601, (1999) https://doi.org/10.1117/12.349992

KEYWORDS: Luminescence, Microscopes, Fluorescence spectroscopy, Chemical analysis, Microscopy, Visible radiation, Ions, Argon ion lasers, Tissues, Oxidation

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Proceedings Article | 14 June 1999 Paper

Chemical decomposition of urinary stones during holmium-laser lithotripsy: II. Evidence for photothermal breakdown

Randolph Glickman, Joel Teichman, George Vassar, Susan Weintraub, Kin Foong Chan, T. Joshua Pfefer, Ashley Welch

Proceedings Volume 3601, (1999) https://doi.org/10.1117/12.350022

KEYWORDS: Laser ablation, Magnesium, Cyanide, Calcium, Laser energy, Calculi, Pulsed laser operation, Absorption, Laser therapeutics, Chemical analysis

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Proceedings Article | 13 May 1998 Paper

Relative photoreactivity of pigment inclusions of the retinal pigment epithelium

Randolph Glickman, Alexander Dontsov, Michail Ostrovsky

Proceedings Volume 3254, (1998) https://doi.org/10.1117/12.308206

KEYWORDS: Visible radiation, Eye, Argon ion lasers, Oxygen, Tissues, Proteins, Medical research, Ophthalmology, Ultraviolet radiation, Oxidation

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Proceedings Article | 16 June 1997 Paper

Action spectrum of oxidative reactions mediated by light-activated melanin

Randolph Glickman, Benjamin Rockwell, Steven Jacques

Proceedings Volume 2975, (1997) https://doi.org/10.1117/12.275469

KEYWORDS: Proteins, Argon ion lasers, Lamps, Absorption, Continuous wave operation, Retina, Visible radiation, Chromophores, Photons, Oxidation

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Proceedings Article | 7 May 1996 Paper

Photodisruption increases the free-radical reactivity of melanosomes isolated from retinal pigment epithelium

Randolph Glickman, Steven Jacques, Jon Schwartz, Tom Rodriguez, Kwok-Wai Lam, Gwen Buhr

Proceedings Volume 2681, (1996) https://doi.org/10.1117/12.239607

KEYWORDS: YAG lasers, Argon ion lasers, Absorbance, Continuous wave operation, Photons, Nd:YAG lasers, Argon, Eye, Thin film coatings, Oxidation

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Proceedings Article | 7 May 1996 Paper

Internal absorption coefficient and threshold for pulsed laser disruption of melanosomes isolated from retinal pigment epithelium

Steven Jacques, Randolph Glickman, Jon Schwartz

Proceedings Volume 2681, (1996) https://doi.org/10.1117/12.239608

KEYWORDS: Laser damage threshold, Absorption, Pulsed laser operation, Nd:YAG lasers, Explosives, Glasses, Skin, Laser energy, Retina, Oxidation

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Proceedings Article | 1 April 1996 Paper

Visual evoked potential measurement of contrast sensitivity in a case of retinal laser injury reveals visual function loss despite normal acuity

Randolph Glickman, Joseph Harrison, Harry Zwick, Harold Longbotham, Charles Ballentine, Bennie Pierce

Proceedings Volume 2674, (1996) https://doi.org/10.1117/12.237516

KEYWORDS: Visualization, Spatial frequencies, Injuries, Contrast sensitivity, Electrodes, Target detection, Retina, Eye, Medical research, Amplifiers

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Proceedings Article | 9 February 1996 Paper

Confocal scanning laser ophthalmoscopic imaging resolution of secondary retinal effects induced by laser radiation

Harry Zwick, David Lund, Bruce Stuck, Joseph Zuclich, Rowe Elliot, Steven Schuschereba, Donald Gagliano, M. Belkin, Randolph Glickman

Proceedings Volume 2732, (1996) https://doi.org/10.1117/12.231676

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Proceedings Article | 22 May 1995 Paper

Confocal scanning laser evaluation of repeated Q-switched laser exposure and possible retinal NFL damage

Harry Zwick, Donald Gagliano, Joseph Zuclich, Bruce Stuck, David Lund, Randolph Glickman

Proceedings Volume 2391, (1995) https://doi.org/10.1117/12.209933

KEYWORDS: Confocal microscopy, Scanning laser ophthalmoscopy, Angiography, Q switched lasers, Nerve, Macula, Indocyanine green, Visualization, Medical research, Q switching

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Proceedings Article | 22 May 1995 Paper

Melanin may promote photooxidation of linoleic acid

Randolph Glickman, Kwok-Wai Lam

Proceedings Volume 2391, (1995) https://doi.org/10.1117/12.209890

KEYWORDS: Xenon, Lamps, Argon ion lasers, Absorption, Ultraviolet radiation, Absorbance, Oxygen, Temperature metrology, Continuous wave operation, Oxidation

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Proceedings Article | 12 January 1995 Paper

Nerve fiber layer (NFL) degeneration associated with acute q-switched laser exposure in the nonhuman primate

Harry Zwick, Joseph Zuclich, Bruce Stuck, Donald Gagliano, David Lund, Randolph Glickman

Proceedings Volume 2330, (1995) https://doi.org/10.1117/12.199259

KEYWORDS: Nerve, Macula, Confocal microscopy, Retina, Scanning laser ophthalmoscopy, Sensors, Angiography, Ophthalmology, Q switched lasers, Visualization

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Proceedings Article | 19 May 1994 Paper

Noninvasive spectroscopic diagnosis of superficial ocular lesions and corneal infections

Judith Mourant, Irving Bigio, D. Gritz, Randolph Glickman, Tamara Johnson, Tsutomu Shimada, K. Story-Held

Proceedings Volume 2135, (1994) https://doi.org/10.1117/12.176002

KEYWORDS: Luminescence, Scattering, Cornea, Bacteria, Scatter measurement, Eye, Tissue optics, Light scattering, Sclera, Spectroscopy

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Proceedings Article | 15 January 1994 Paper

Optical diagnostics based on elastic scattering: recent clinical demonstrations with the Los Alamos optical biopsy system

Irving Bigio, Thomas Loree, Judith Mourant, Tsutomu Shimada, K. Story-Held, Randolph Glickman, Richard Conn

Proceedings Volume 2081, (1994) https://doi.org/10.1117/12.166823

KEYWORDS: Tissue optics, Biopsy, Luminescence, Scattering, Tissues, Cancer, Pathology, Diagnostics, Natural surfaces, Prostate

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Showing 5 of 61 publications

Conference Committee Involvement (24)

Optical Interactions with Tissue and Cells XXXVI

25 January 2025 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXXV

27 January 2024 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXXIV

28 January 2023 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXXIII and Advanced Photonics in Urology

22 January 2022 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXXII

6 March 2021 | Online Only, California, United States

Optical Interactions with Tissue and Cells XXXI

1 February 2020 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXX

2 February 2019 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXIX

29 January 2018 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXVIII

30 January 2017 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXVII

14 February 2016 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXVI

8 February 2015 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXV

3 February 2014 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXIV

5 February 2013 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXIII

23 January 2012 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXII

24 January 2011 | San Francisco, California, United States

Optical Interactions with Tissues and Cells XXI

25 January 2010 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XX

26 January 2009 | San Jose, California, United States

Optical Interactions with Tissue and Cells XIX

21 January 2008 | San Jose, California, United States

Optical Interactions with Tissue and Cells XVIII

21 January 2007 | San Jose, California, United States

Optical Interactions with Tissue and Cells XVII

23 January 2006 | San Jose, California, United States

Optical Interactions with Tissue and Cells XVI

24 January 2005 | San Jose, CA, United States

Laser Interaction with Tissue and Cells XV

26 January 2004 | San Jose, CA, United States

Laser Tissue Interaction XIV: Photochemical, Photothermal, Photomechanical

28 January 2003 | San Jose, CA, United States

Laser and Noncoherent Light Ocular Effects: Epidemiology, Prevention, and Treatment III

25 January 1999 | San Jose, CA, United States

Showing 5 of 24 Conference Committees

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