Dr. William P. Roach Profile

Dr. William P. Roach

Program Officer

SPIE Involvement:

Publications (71)

Proceedings Article | 3 March 2014 Paper

Beam combination of multiple vertical external cavity surface emitting lasers via volume Bragg gratings

Chunte Lu, William Roach, Genesh Balakrishnan, Alexander Albrecht, Jerome Moloney, Leonid Glebov

Proceedings Volume 8966, 89660Y (2014) https://doi.org/10.1117/12.2039666

KEYWORDS: Reflectivity, Vertical external cavity surface emitting lasers, Fiber Bragg gratings, Holography, Diffraction, Output couplers, Optical design, Near infrared, Multiplexing, Optical filters

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SPIE Journal Paper | 4 February 2014

Electric field measurements during filament-guided discharge

Andreas Schmitt-Sody, Adrian Lucero, David French, William Latham, William White, William Roach

OE, Vol. 53, Issue 05, 051504, (February 2014) https://doi.org/10.1117/12.10.1117/1.OE.53.5.051504

KEYWORDS: Electrodes, Plasmas, Physics, Refractive index, Optical engineering, Ultrafast phenomena, Diffraction, Radio propagation, Terahertz radiation, Pulsed laser operation

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Proceedings Article | 26 February 2013 Paper

Active coherent superposition of five fiber amplifiers at 670W using multiplexed volume Bragg grating

Chunte Lu, Angel Flores, Erik Bochove, William Roach, Vadim Smirnov, Leonid Glebov

Proceedings Volume 8601, 86011A (2013) https://doi.org/10.1117/12.2001854

KEYWORDS: Fiber lasers, Diffraction gratings, Fiber amplifiers, Fiber Bragg gratings, Multiplexing, Optical amplifiers, Diffraction, Beam splitters, Mode locking, Polarization

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SPIE Journal Paper | 1 April 2011 Open Access

Development of a compact terahertz time-domain spectrometer for the measurement of the optical properties of biological tissues

Gerald Wilmink, Bennett Ibey, Benjamin Rivest, Jessica Grundt, William Roach, Thomas Tongue, Brian Schulkin, Norman Laman, Xomalin Peralta, Caleb Roth, Cesario Cerna

JBO, Vol. 16, Issue 04, 047006, (April 2011) https://doi.org/10.1117/12.10.1117/1.3570648

KEYWORDS: Terahertz radiation, Tissues, Skin, Optical properties, Spectroscopy, Water, Refraction, Absorption, Bioalcohols, Optical testing

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Proceedings Article | 28 February 2011 Paper

Accelerating thermal deposition modeling at terahertz frequencies using GPUs

Michael Doroski, Michael Knight, Jason Payne, Jessica Grundt, Bennett Ibey, Robert Thomas, William Roach, Gerald Wilmink

Proceedings Volume 7897, 78970F (2011) https://doi.org/10.1117/12.874262

KEYWORDS: Terahertz radiation, Tissues, 3D modeling, Finite-difference time-domain method, Thermal modeling, Computer simulations, Laser damage threshold, Absorption, Radio propagation, In vitro testing

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Proceedings Article | 26 February 2010 Paper

Damage thresholds for terahertz radiation

Danielle Dalzell, Jill McQuade, Rebecca Vincelette, Bennet Ibey, Jason Payne, Robert Thomas, W. Roach, Caleb Roth, Gerald Wilmink

Proceedings Volume 7562, 75620M (2010) https://doi.org/10.1117/12.849243

KEYWORDS: Terahertz radiation, Tissues, Free electron lasers, Laser damage threshold, Standards development, Safety, Computational modeling, Gas lasers, Skin, Laser tissue interaction

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Proceedings Article | 23 February 2010 Paper

Quantitative investigation of the bioeffects associated with terahertz radiation

Gerald Wilmink, Benjamin Rivest, Bennett Ibey, Caleb Roth, Joshua Bernhard, William Roach

Proceedings Volume 7562, 75620L (2010) https://doi.org/10.1117/12.844916

KEYWORDS: Terahertz radiation, Infrared cameras, Finite-difference time-domain method, Temperature metrology, Data modeling, Proteins, Cameras, Gas lasers, Sensors, Carbon dioxide lasers

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Proceedings Article | 23 February 2010 Paper

Measurement of the optical properties of skin using terahertz time-domain spectroscopic techniques

Gerald Wilmink, Bennett Ibey, Thomas Tongue, Brian Schulkin, Xomalin Peralta, Benjamin Rivest, Eric Haywood, William Roach

Proceedings Volume 7562, 75620J (2010) https://doi.org/10.1117/12.844914

KEYWORDS: Terahertz radiation, Skin, Tissues, Optical properties, Spectroscopy, Optical testing, Refraction, Analytical research, Absorption, Terahertz spectroscopy

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Proceedings Article | 23 February 2010 Paper

Determination of death thresholds and identification of terahertz (THz)-specific gene expression signatures

Gerald Wilmink, Bennett Ibey, Caleb Roth, Rebecca Vincelette, Benjamin Rivest, Christopher Horn, Joshua Bernhard, Dawnlee Roberson, William Roach

Proceedings Volume 7562, 75620K (2010) https://doi.org/10.1117/12.844917

KEYWORDS: Terahertz radiation, Picosecond phenomena, Cell death, Luminescence, Flow cytometry, Microscopy, Carbon dioxide lasers, Radiation effects, Infrared radiation, Proteins

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Proceedings Article | 25 February 2009 Paper

Optical property of human skin

Luisiana Cundin, William Roach, Gerald Wilmink

Proceedings Volume 7175, 717517 (2009) https://doi.org/10.1117/12.805582

KEYWORDS: Absorption, Skin, Refraction, Liquids, Optical properties, Water, Fourier transforms, Statistical analysis, Biological research, Analytical research

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Proceedings Article | 25 February 2009 Paper

A signature microRNA expression profile for the cellular response to thermal stress

Gerald Wilmink, Caleb Roth, Norma Ketchum, Bennett Ibey, Angela Waterworth, Maria Suarez, William Roach

Proceedings Volume 7175, 71750U (2009) https://doi.org/10.1117/12.815310

KEYWORDS: Proteins, Cell death, Detection and tracking algorithms, Thermodynamics, Control systems, Mode conditioning cables, Luminescence, Computer programming, Databases, Cell mechanics

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Proceedings Article | 25 February 2009 Paper

Empirical comparison of Pennes' bio-heat equation

Luisiana Cundin, William Roach, Nancy Millenbaugh

Proceedings Volume 7175, 717516 (2009) https://doi.org/10.1117/12.805577

KEYWORDS: Blood, Thermal modeling, Statistical analysis, Tissues, 3D modeling, Biological research, Data modeling, Absorption, Convection, Scattering

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Proceedings Article | 25 February 2009 Paper

The optical properties of biological tissues in the terahertz wavelength range

Gerald Wilmink, Benjamin Rivest, Bennett Ibey, Luisiana Cundin, Eric Haywood, William Roach

Proceedings Volume 7175, 717507 (2009) https://doi.org/10.1117/12.806175

KEYWORDS: Terahertz radiation, Tissues, Optical properties, Waveguides, Absorption, Lenses, Sensors, Spectroscopy, Nitrogen, Laser optics

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Proceedings Article | 24 February 2009 Paper

Quantification of cell sensitivity to nanosecond duration electrical pulses

Bennett Ibey, William Roach, Andrei Pakhomov

Proceedings Volume 7180, 71800U (2009) https://doi.org/10.1117/12.808016

KEYWORDS: Resistance, Plasma, Electrodes, Data acquisition, Ions, Simulation of CCA and DLA aggregates, Tungsten, Electromagnetism, Calcium, Molecules

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Proceedings Article | 20 February 2008 Paper

Comparing finite difference time domain and Monte Carlo modeling of human skin interaction with terahertz radiation

Bennett Ibey, Jason Payne, Dustin Mixon, Robert Thomas, William Roach

Proceedings Volume 6854, 68540Z (2008) https://doi.org/10.1117/12.772076

KEYWORDS: Terahertz radiation, Finite-difference time-domain method, Tissues, Absorption, Synthetic aperture radar, Monte Carlo methods, Scattering, Skin, Water, Tissue optics

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Proceedings Article | 21 February 2007 Paper

Infrared laser damage thresholds for skin at wavelengths from 0.810 to 1.54 microns for femtosecond to microsecond pulse durations

Clarence Cain, William Roach, David Stolarski, Gary Noojin, Semih Kumru, Kevin Stockton, Justin Zohner, Benjamin Rockwell

Proceedings Volume 6435, 64350W (2007) https://doi.org/10.1117/12.715199

KEYWORDS: Skin, Pulsed laser operation, Laser damage threshold, Laser ablation, Femtosecond phenomena, Standards development, Laser induced breakdown spectroscopy, Plasma, Visible radiation, Infrared radiation

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Proceedings Article | 19 February 2007 Paper

Theoretical and experimental bioeffects research for high-power terahertz electromagnetic energy

Jill McQuade, Nichole Jindra, Semih Kumru, Ron Seaman, Alex Salazar, Victor Villavicencio, C. Clark, Kalyn Yaws, Jason Payne, Robert Thomas, William Roach

Proceedings Volume 6435, 64350X (2007) https://doi.org/10.1117/12.725180

KEYWORDS: Laser damage threshold, Terahertz radiation, Tissue optics, Tissues, Standards development, Skin, Radio optics, Absorption, Safety, Laser safety

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Proceedings Article | 19 February 2007 Paper

A thermal model of laser absorption

Dustin Mixon, William Roach

Proceedings Volume 6435, 643506 (2007) https://doi.org/10.1117/12.700910

KEYWORDS: Temperature metrology, Laser tissue interaction, Thermal modeling, Absorption, Tissues, Continuous wave operation, Partial differential equations, Blood, Wave propagation, Laser therapeutics

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Proceedings Article | 12 February 2007 Paper

Electromagnetic properties of tissue in the optical region

K. Yaws, D. Mixon, W. Roach

Proceedings Volume 6435, 643507 (2007) https://doi.org/10.1117/12.715202

KEYWORDS: Tissue optics, Water, Electromagnetism, Data modeling, Signal attenuation, Dielectrics, Skin, Terahertz radiation, Absorption, Tissues

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SPIE Journal Paper | 1 July 2006 Open Access

Porcine skin visible lesion thresholds for near-infrared lasers including modeling at two pulse durations and spot sizes

Clarence Cain, Garrett Polhamus, William Roach, David Stolarski, Kurt Schuster, Kevin Stockton, Benjamin Rockwell, Bo Chen, Ashley Welch

JBO, Vol. 11, Issue 04, 041109, (July 2006) https://doi.org/10.1117/12.10.1117/1.2338815

KEYWORDS: Skin, Pulsed laser operation, Laser safety, Thermal modeling, Infrared cameras, Laser induced breakdown spectroscopy, Injuries, Standards development, Temperature metrology, Laser damage threshold

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SPIE Journal Paper | 1 March 2006 Open Access

Visible lesion thresholds with pulse duration, spot size dependency, and model predictions for 1.54-µm, near-infrared laser pulses penetrating porcine skin

Clarence Cain, Kurt Schuster, Justin Zohner, Kevin Stockton, David Stolarski, Robert Thomas, Benjamin Rockwell, William Roach

JBO, Vol. 11, Issue 02, 024001, (March 2006) https://doi.org/10.1117/12.10.1117/1.2187987

KEYWORDS: Skin, Pulsed laser operation, Thermal modeling, Laser damage threshold, Tissues, Eye, Q switched lasers, Laser energy, Standards development, Cornea

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SPIE Journal Paper | 1 November 2004 Open Access

Retinal response of Macaca mulatta to picosecond laser pulses of varying energy and spot size

William Roach, Clarence Cain, Drew Narayan, Gary Noojin, Stephen Boppart, Reginald Birngruber, James Fujimoto, Cynthia Toth

JBO, Vol. 9, Issue 06, (November 2004) https://doi.org/10.1117/12.10.1117/1.1805554

KEYWORDS: Optical coherence tomography, Reflectivity, Retina, Injuries, Laser induced breakdown spectroscopy, Picosecond phenomena, Tissues, Photomicroscopy, Eye, Laser energy

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Proceedings Article | 1 July 2004 Paper

Porcine skin thermal response to near-IR lasers using a fast infrared camera

Clarence Cain, Thomas Milner, Sergey Telenkov, Kurt Schuster, Kevin Stockton, David Stolarski, Chris Condit, Benjamin Rockwell, William Roach, A. Welch

Proceedings Volume 5319, (2004) https://doi.org/10.1117/12.529356

KEYWORDS: Skin, Temperature metrology, Infrared cameras, Monte Carlo methods, Scattering, Absorption, Pulsed laser operation, Light scattering, Data modeling, Cameras

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Proceedings Article | 1 July 2004 Paper

Model predictions and measured skin damage thresholds for 1.54-um laser pulses in porcine skin

William Roach, Clarence Cain, Kurt Schuster, Kevin Stockton, David Stolarski, Robert Galloway, Benjamin Rockwell

Proceedings Volume 5319, (2004) https://doi.org/10.1117/12.529398

KEYWORDS: Skin, Thermal modeling, Laser damage threshold, Pulsed laser operation, Neodymium, Laser safety, Mathematical modeling, Laser induced damage, Standards development, Data modeling

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Proceedings Article | 1 July 2004 Paper

Proteomic analyses of the acute tissue response for explant rabbit corneas and engineered corneal tissue models following in vitro exposure to 1540-nm laser light

Thomas Eurell, Thomas Johnson, Willliam Roach

Proceedings Volume 5319, (2004) https://doi.org/10.1117/12.529548

KEYWORDS: Tissues, Laser tissue interaction, Proteins, Cornea, In vitro testing, Pulsed laser operation, Infrared lasers, Mass spectrometry, Homogenization, Analytical research

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Proceedings Article | 1 July 2004 Paper

Retinal injury from simultaneous exposure to 532-nm and 860-nm laser irradiation

Kurt Schuster, William Roach, Garrett Polhamus, John Notabartolo, Cheryl DiCarlo, Kevin Stockton, David Stolarski, Val Carothers, Benjamin Rockwell, Clarence Cain

Proceedings Volume 5319, (2004) https://doi.org/10.1117/12.529431

KEYWORDS: Eye, Standards development, Laser irradiation, Beam splitters, Injuries, Retina, Cameras, Laser tissue interaction, Sensors, Photography

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Proceedings Article | 27 August 2003 Paper

Model predictions and measured skin damage thresholds for 1.54-μm laser pulses in porcine skin

William Roach, James Thomas, Kurt Schuster, Kevin Stockton, David Stolarski, Michael Foltz, Benjamin Rockwell, Clarence Cain

Proceedings Volume 4961, (2003) https://doi.org/10.1117/12.477656

KEYWORDS: Skin, Laser damage threshold, Pulsed laser operation, Injuries, Thermal modeling, Standards development, Mathematical modeling, Laser applications, Laser safety, Cornea

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Proceedings Article | 20 June 2003 Paper

Histomorphometric and proteomic analysis of the acute rabbit corneal tissue response following in vitro exposure to 1540-nm laser light

Thomas Eurell, Thomas Johnson, William Roach

Proceedings Volume 4953, (2003) https://doi.org/10.1117/12.477905

KEYWORDS: Proteins, Tissues, Laser tissue interaction, Cornea, Infrared lasers, In vitro testing, Pulsed laser operation, Analytical research, Molecular lasers, Mass spectrometry

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Proceedings Article | 20 June 2003 Paper

Measured skin damage thresholds for 1314-nm laser exposures

Cecilia Montes de Oca, Clarence Cain, Kurt Schuster, Kevin Stockton, James Thomas, Thomas Eggleston, William Roach

Proceedings Volume 4953, (2003) https://doi.org/10.1117/12.477902

KEYWORDS: Skin, Biopsy, Laser safety, Pulsed laser operation, Laser damage threshold, Standards development, Laser systems engineering, Injuries, Cornea, Tissues

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Proceedings Article | 20 June 2003 Paper

Comparative analysis of spot size dependence for lesions produced by infrared laser pulses

James Thomas, Clarence Cain, David Stolarski, Gary Noojin, Kurt Schuster, Thomas Eggleston, Kevin Stockton, William Roach

Proceedings Volume 4953, (2003) https://doi.org/10.1117/12.476885

KEYWORDS: Skin, Laser damage threshold, Eye models, Standards development, Mathematical modeling, Electro optical modeling, Thermal modeling, Laser safety, Infrared lasers, Laser systems engineering

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Proceedings Article | 20 June 2003 Paper

Investigation of laser injuries

Thomas Johnson, Natalie Keeler, Jerome Dennis, Colin Figueroa, Howard Press, R. James Rockwell, Bruce Stuck, William Roach, Ardith Wartick

Proceedings Volume 4953, (2003) https://doi.org/10.1117/12.476909

KEYWORDS: Injuries, Databases, Manufacturing, Eyewear, Laser engineering, Eye, Surgery, Laser applications, Laser therapeutics, Laser safety

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SPIE Press Book | 9 January 2003

Selected Papers on Ultrashort Laser Pulse Bioeffects

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Proceedings Article | 27 June 2002 Paper

Morphometric comparison of the acute rabbit corneal response to 1540-nm laser light following in-vitro exposure to millisecond or nanosecond pulse widths

Thomas Eurell, Thomas Johnson, William Roach

Proceedings Volume 4617, (2002) https://doi.org/10.1117/12.472541

KEYWORDS: Tissues, Infrared lasers, Laser tissue interaction, Pulsed laser operation, Cornea, In vitro testing, Health sciences, Eye, Tissue optics, Laser applications

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Proceedings Article | 27 June 2002 Paper

Survey of laser injury

Thomas Johnson, J. Dunn, William Roach

Proceedings Volume 4617, (2002) https://doi.org/10.1117/12.472516

KEYWORDS: Injuries, Databases, Safety, Laser safety, Surveillance, Manufacturing, Laser countermeasures, Statistical analysis, Laser tissue interaction, Standards development

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Proceedings Article | 27 June 2002 Paper

Corneal injury from 1318-nm single laser pulses

William Roach, Bryan Ketzenberger, Margaret Burton, Thomas Johnson

Proceedings Volume 4617, (2002) https://doi.org/10.1117/12.472542

KEYWORDS: Cornea, Laser tissue interaction, Injuries, Tissues, Medicine, Neodymium, Nd:YAG lasers, Laser safety, Laser damage threshold, Near infrared

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Proceedings Article | 9 July 2001 Paper

Skin exposures from 1318-nm laser pulses

Thomas Johnson, Bryan Ketzenberger, Kenneth Pletcher, Steven Wild, William Roach

Proceedings Volume 4257, (2001) https://doi.org/10.1117/12.434720

KEYWORDS: Skin, Cornea, Laser tissue interaction, Injuries, Absorption, Medicine, Statistical analysis, Tissue optics, Nd:YAG lasers

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Proceedings Article | 9 July 2001 Paper

Porcine dermal lesions produced by 1540-nm laser radiation pulses

William Roach, Thomas Johnson

Proceedings Volume 4257, (2001) https://doi.org/10.1117/12.434721

KEYWORDS: Skin, Laser tissue interaction, Injuries, Absorption, Animal model studies, Tissues, Medicine, Health sciences, Laser development, Biopsy

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Proceedings Article | 21 May 2001 Paper

ED50 determination of corneal lesions produced by 1318-nm laser radiation pulses

Bryan Ketzenberger, Thomas Johnson, Steven Wild, Kenneth Pletcher, William Roach

Proceedings Volume 4244, (2001) https://doi.org/10.1117/12.427844

KEYWORDS: Cornea, Data modeling, Injuries, Laser tissue interaction, Laser systems engineering, Laser safety, Animal model studies, Nd:YAG lasers, Medicine, Laser damage threshold

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Proceedings Article | 17 May 2001 Paper

Morphometric comparison of the acute rabbit and pig corneal response to 1540-nm laser light following ex-vivo exposure

Thomas Eurell, William Roach, Thomas Johnson

Proceedings Volume 4246, (2001) https://doi.org/10.1117/12.426718

KEYWORDS: Cornea, Laser vision correction, Laser tissue interaction, Pulsed laser operation, Tissues, Infrared lasers, Surgery, Laser therapeutics, Laser applications, Laser cutting

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Proceedings Article | 17 May 2001 Paper

Corneal exposures from 1540-nm laser pulses

William Roach, Thomas Eurell, Thomas Johnson

Proceedings Volume 4246, (2001) https://doi.org/10.1117/12.426707

KEYWORDS: In vivo imaging, Cornea, In vitro testing, Cerium, Tissues, Lamps, Medicine, Eye models, Eye, Pulsed laser operation

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Proceedings Article | 13 June 2000 Paper

Corneal and skin laser exposures from 1540-nm laser pulses

Thomas Johnson, Michael Mitchell, Pedro Rico, David Fletcher, Thomas Eurell, William Roach

Proceedings Volume 3914, (2000) https://doi.org/10.1117/12.388049

KEYWORDS: Skin, Cornea, Laser tissue interaction, In vivo imaging, Cerium, Absorption, Tissues, In vitro testing, Injuries, Statistical analysis

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Proceedings Article | 17 May 2000 Paper

Corneal equivalents: a replacement model for in-vivo 1540-nm laser exposure studies

David Fletcher, Thomas Johnson, Michael Mitchell, Thomas Eurell, Pedro Rico, William Roach

Proceedings Volume 3907, (2000) https://doi.org/10.1117/12.386288

KEYWORDS: Cornea, Cerium, In vivo imaging, Tissues, In vitro testing, Animal model studies, Confocal microscopy, Laser induced damage, Collagen, Laser damage threshold

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Proceedings Article | 17 May 2000 Paper

ED50 determination and histological characterization of porcine dermal lesions produced by 1540-nm laser radiation pulses

Pedro Rico, Michael Mitchell, Thomas Johnson, William Roach

Proceedings Volume 3907, (2000) https://doi.org/10.1117/12.386278

KEYWORDS: Skin, Laser safety, Laser tissue interaction, Standards development, Safety, Laser systems engineering, Animal model studies, Thermal modeling, Medicine, Systems modeling

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Proceedings Article | 3 March 2000 Paper

Retinal damage from femtosecond to nanosecond laser exposure

Robert Thomas, Gary Noojin, David Stolarski, Gordon Hengst, Cynthia Toth, William Roach, Benjamin Rockwell

Proceedings Volume 3902, (2000) https://doi.org/10.1117/12.379341

KEYWORDS: Ultrafast phenomena, Laser induced damage, Laser damage threshold, Femtosecond phenomena, Laser safety, Laser induced breakdown spectroscopy, Retina, Visible radiation, Eye, Pulsed laser operation

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SPIE Journal Paper | 1 October 1999 Open Access

Comparison of optical coherence tomography imaging of cataracts with histopathology

Cheryl DiCarlo, William Roach, Donald Gagliano, Stephen Boppart, Daniel Hammer, Ann Cox, James Fujimoto

JBO, Vol. 4, Issue 04, (October 1999) https://doi.org/10.1117/12.10.1117/1.429951

KEYWORDS: Optical coherence tomography, Photomicroscopy, Opacity, Reflectivity, Eye, Lab on a chip, Tissues, Coherence imaging, Photography, Lenses

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Proceedings Article | 22 June 1999 Paper

Comparison of in-vivo skin models for near-infrared laser exposure

Thomas Eggleston, Michael Mitchell, Thomas Johnson, Robert Becker, William Roach

Proceedings Volume 3590, (1999) https://doi.org/10.1117/12.350981

KEYWORDS: Skin, In vivo imaging, Laser safety, Statistical analysis, Statistical modeling, Safety, Standards development, Distance measurement, Thermal modeling, Medicine

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Proceedings Article | 14 June 1999 Paper

Retinal damage mechanisms and safety for ultrashort laser exposure

Benjamin Rockwell, Cynthia Toth, William Roach, Dale Payne, Richard Hopkins, Paul Kennedy, David Stolarski, Gary Noojin, Robert Thomas, Clarence Cain

Proceedings Volume 3601, (1999) https://doi.org/10.1117/12.349987

KEYWORDS: Laser safety, Ultrafast phenomena, Laser damage threshold, Eye, Retina, Femtosecond phenomena, Safety, Near infrared, Pulsed laser operation, Standards development

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Proceedings Article | 14 June 1999 Paper

Determination of single-pulse exposure threshold (ED50) for cornea for 1400- to 2000-nm lasers

Thomas Johnson, Thomas Eggleston, David Fletcher, Ken Lopez, Pedro Rico, Michael Mitchell, William Roach

Proceedings Volume 3601, (1999) https://doi.org/10.1117/12.350045

KEYWORDS: Skin, Cornea, Cameras, In vivo imaging, Laser damage threshold, Confocal microscopy, Laser tissue interaction, Tissues, Microscopy, In vitro testing

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Proceedings Article | 4 June 1999 Paper

Safe use of ultrashort lasers

Benjamin Rockwell, Clarence Cain, William Roach, Robert Thomas

Proceedings Volume 3616, (1999) https://doi.org/10.1117/12.351838

KEYWORDS: Laser safety, Laser systems engineering, Femtosecond phenomena, Laser damage threshold, Retina, Ultrafast phenomena, Safety, Pulsed laser operation, Eye, Standards development

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Proceedings Article | 18 May 1998 Paper

Retinal damage mechanisms from ultrashort laser exposure

Benjamin Rockwell, Dale Payne, Richard Hopkins, Daniel Hammer, Paul Kennedy, Rodney Amnotte, Brent Eilert, Jeffrey Druessel, Cynthia Toth, William Roach, Shana Phillips, David Stolarski, Gary Noojin, Robert Thomas, Clarence Cain

Proceedings Volume 3255, (1998) https://doi.org/10.1117/12.308221

KEYWORDS: Pulsed laser operation, Eye, Laser safety, Ultrafast phenomena, Laser damage threshold, Laser induced damage, Retina, Femtosecond phenomena, Standards development, Laser induced breakdown spectroscopy

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Proceedings Article | 13 May 1998 Paper

Windows of opportunity: applying ultrashort laser pulses for selective tissue effects

Cynthia Toth, Eric Chiu, Katrina Winter, Clarence Cain, Gary Noojin, William Roach, Benjamin Rockwell

Proceedings Volume 3254, (1998) https://doi.org/10.1117/12.308155

KEYWORDS: Ultrafast phenomena, Retina, Injuries, Laser energy, Laser tissue interaction, Pulsed laser operation, Argon ion lasers, In vivo imaging, Vitreous, Eye

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Proceedings Article | 16 June 1997 Paper

Optical coherence tomography of the retinal response to ultrashort laser pulses

Cynthia Toth, Drew Narayan, William Roach, Reginald Birngruber, Stephen Boppart, Michael Hee, Cheryl DiCarlo, Clarence Cain, Gary Noojin, James Fujimoto

Proceedings Volume 2975, (1997) https://doi.org/10.1117/12.275466

KEYWORDS: Optical coherence tomography, Reflectivity, Injuries, Retina, Ultrafast phenomena, Picosecond phenomena, Tissue optics, Laser tissue interaction, Pulsed laser operation, In vivo imaging

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Proceedings Article | 2 May 1997 Paper

Ultrashort-laser-pulse retinal damage

Benjamin Rockwell, William Roach, Dale Payne, Paul Kennedy, Jeffrey Druessel, Rodney Amnotte, Brent Eilert, Shana Phillips, David Stolarski, Gary Noojin, Clarence Cain, Cynthia Toth

Proceedings Volume 2974, (1997) https://doi.org/10.1117/12.275228

KEYWORDS: Eye, Information operations, Pulsed laser operation, Laser damage threshold, Ultrafast phenomena, Wave propagation, Laser induced breakdown spectroscopy, Retina, Femtosecond phenomena, Laser safety

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Proceedings Article | 7 May 1996 Paper

Subnanosecond single laser pulse minimum-visible-lesion studies in the near infrared

William Roach, Cheryl DiCarlo, Gary Noojin, David Stolarski, Rodney Amnotte, Val Caruthers, Benjamin Rockwell, Clarence Cain

Proceedings Volume 2681, (1996) https://doi.org/10.1117/12.239597

KEYWORDS: Picosecond phenomena, Pulsed laser operation, Near infrared, Visible radiation, Standards development, Laser safety, Retina, Photography, Laser systems engineering, Laser damage threshold

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Proceedings Article | 7 May 1996 Paper

In-vivo laser-induced bubbles in the primate eye with femtosecond pulses

Clarence Cain, Cheryl DiCarlo, Gary Noojin, Rodney Amnotte, Benjamin Rockwell, William Roach

Proceedings Volume 2681, (1996) https://doi.org/10.1117/12.239599

KEYWORDS: Eye, Laser induced breakdown spectroscopy, Retina, Video, Femtosecond phenomena, Vitreous, In vivo imaging, Eye models, Laser damage threshold, Cameras

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Proceedings Article | 7 May 1996 Paper

Time-resolved spectroscopy of laser-induced breakdown in water

Robert Thomas, Daniel Hammer, Gary Noojin, David Stolarski, Benjamin Rockwell, William Roach

Proceedings Volume 2681, (1996) https://doi.org/10.1117/12.239601

KEYWORDS: Plasma, Pulsed laser operation, Laser induced damage, Laser induced breakdown spectroscopy, Spectrographs, Streak cameras, Laser scattering, Time resolved spectroscopy, Picosecond phenomena, Laser energy

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Proceedings Article | 7 May 1996 Paper

Histopathology of ultrashort-laser-pulse retinal damage

Cynthia Toth, Drew Narayan, Catherine Osborne, Benjamin Rockwell, Cindy Stein, Rodney Amnotte, Cheryl DiCarlo, William Roach, Gary Noojin, Clarence Cain

Proceedings Volume 2681, (1996) https://doi.org/10.1117/12.239598

KEYWORDS: Laser tissue interaction, Picosecond phenomena, Retina, Laser energy, Ultrafast phenomena, Pulsed laser operation, Eye, Laser safety, Blood, Vitreous

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Proceedings Article | 22 May 1995 Paper

In vivo laser-induced breakdown in the rabbit eye

Clarence Cain, Cheryl DiCarlo, Paul Kennedy, Gary Noojin, Rodney Amnotte, William Roach

Proceedings Volume 2391, (1995) https://doi.org/10.1117/12.209913

KEYWORDS: Eye, Laser induced breakdown spectroscopy, Vitreous, In vivo imaging, Femtosecond phenomena, Laser damage threshold, Eye models, Video, Retina, Pulsed laser operation

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Proceedings Article | 22 May 1995 Paper

In vivo imaging of the development of linear and nonlinear retinal laser effects using optical coherence tomography in correlation with histopathological findings

Reginald Birngruber, Michael Hee, Stephen Boppart, James Fujimoto, Eric Swanson, Cynthia Toth, Cheryl DiCarlo, Clarence Cain, Gary Noojin, William Roach

Proceedings Volume 2391, (1995) https://doi.org/10.1117/12.209892

KEYWORDS: Optical coherence tomography, Retina, Eye, In vivo imaging, Argon ion lasers, Nonlinear optics, Laser optics, Tissues, Image resolution, Injuries

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Optical Coherence Tomography (OCT) is a new, non-invasive diagnostic technique for high resolution optical 3D imaging, which was developed and applied to several different biological materials during the lasi; five years [1, 2, 3]. A unique application ofthis technique is the microscopical cross-sectional imaging ofpostenor structures ofthe eye which are not accessable with other high resolution techniques in-vivo neither with x-ray-imaging nor with high frequency ultrasound scanning. The superior spatial resolution on the order ofabout lOtm laterally and axially, the high signal-to-noise ratio ofmore than 100 db and the fast acquisition-time of one second for a two dimensional scan provides a technique for cross-sectional in-vivo-momtoring ofintraocular structures and therefore the possibility to study the time course of anatomical and pathological developments in the eye. The acute morphological changes of ocular structures and their biological healing response after shortterm impacts such as high-intensity laser exposures are ofparticular interest for the understanding of the mechanisms responsible for therapeutic laser-application in ophthal-mology as well as for laser injury to the eye. A correlation between cross-sectional OCT-images and structural findings using classical histopathological techniques facilitates a better interpretation ofthe characteristic patterns seen in OCTimages and defines the sensitivity ofthe OCT-technique to image morphological details. On the other hand preparational artefacts not avoidable in all histological procedures can be identified and analyzed by comparing histological micrographs with OCT-images of exactly the same structure. First results of an experimental study where retinal effects were produced in monkey eyes using laser pulses from 200 ms to 130 fs in duration are presented in this article. The applied energies from 5tJ to 50 mJ were able to induce the whole spectrum of biological effects possible in the eye, ranging from intraretinal microruptures to extensive thermal denaturation and massive preretinal hemorrhages [4, 5, 6].

Proceedings Article | 22 May 1995 Paper

Retinal threshold studies for nanosecond and picosecond visible laser pulses

William Roach, Cheryl DiCarlo, Gary Noojin, David Stolarski, Rodney Amnotte, Audrey Smith, Mark Rogers, Clarence Cain

Proceedings Volume 2391, (1995) https://doi.org/10.1117/12.209871

KEYWORDS: Picosecond phenomena, Standards development, Laser damage threshold, Photography, Laser safety, Retina, Nd:YAG lasers, Eye, Visible radiation, Cornea

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Proceedings Article | 22 May 1995 Paper

Effect of nonlinear optical phenomena on retinal damage

Benjamin Rockwell, Paul Kennedy, Robert Thomas, William Roach, Mark Rogers

Proceedings Volume 2391, (1995) https://doi.org/10.1117/12.209944

KEYWORDS: Absorption, Retina, Pulsed laser operation, Laser scattering, Information operations, Scattering, Laser induced damage, Laser damage threshold, Supercontinuum generation, Picosecond phenomena

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Proceedings Article | 22 May 1995 Paper

Integrated light spectroscopy of laser-induced breakdown in aqueous media

David Stolarski, Jennifer Hardman, Craig Bramlette, Gary Noojin, Robert Thomas, Benjamin Rockwell, William Roach

Proceedings Volume 2391, (1995) https://doi.org/10.1117/12.209873

KEYWORDS: Plasmas, Laser induced breakdown spectroscopy, Picosecond phenomena, Pulsed laser operation, Spectroscopy, Black bodies, Laser energy, Laser induced damage, Spectrographs, Liquids

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Proceedings Article | 22 May 1995 Paper

First-order model for computation of laser-induced breakdown thresholds in condensed media

Paul Kennedy, Stephen Boppart, Daniel Hammer, Benjamin Rockwell, Gary Noojin, William Roach

Proceedings Volume 2391, (1995) https://doi.org/10.1117/12.209922

KEYWORDS: Ionization, Electrons, Eye models, Laser induced breakdown spectroscopy, Solid modeling, Laser damage threshold, Plasma, Laser induced damage, Liquids, Polonium

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Proceedings Article | 12 May 1995 Paper

New noninvasive imaging technique for cataract evaluation in the rhesus monkey

Cheryl DiCarlo, Stephen Boppart, Donald Gagliano, Rodney Amnotte, Audrey Smith, Daniel Hammer, Ann Cox, Michael Hee, James Fujimoto, Eric Swanson, William Roach

Proceedings Volume 2395, (1995) https://doi.org/10.1117/12.209062

KEYWORDS: Optical coherence tomography, Opacity, Lab on a chip, Reflectivity, Eye, Photography, Lamps, In vivo imaging, Tissue optics, Tissues

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Proceedings Article | 17 August 1994 Paper

Femtosecond laser threshold: retinal damage versus induced breakdown mechanisms

Clarence Cain, Cynthia Toth, Cindy Stein, Gary Noojin, David Stolarski, Benjamin Rockwell, Stephen Boppart, William Roach

Proceedings Volume 2134, (1994) https://doi.org/10.1117/12.182940

KEYWORDS: Eye, Femtosecond phenomena, Laser damage threshold, Laser induced breakdown spectroscopy, Vitreous, Water, Laser induced damage

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Proceedings Article | 17 August 1994 Paper

Retinal hemorrhagic lesions from femtosecond visible laser pulses

Cindy Stein, Cynthia Toth, Clarence Cain, Gary Noojin, David Stolarski, Benjamin Rockwell, William Roach

Proceedings Volume 2134, (1994) https://doi.org/10.1117/12.182946

KEYWORDS: Absorption, Femtosecond phenomena, Eye, In vivo imaging, Eye models

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Proceedings Article | 17 August 1994 Paper

Determination of self-focusing effects for light propagating in the eye

Benjamin Rockwell, William Roach, Mark Rogers

Proceedings Volume 2134, (1994) https://doi.org/10.1117/12.182921

KEYWORDS: Eye, Retina, Ultrafast phenomena, Laser beam propagation, Matrices, Refractive index, Diffraction, Picosecond phenomena, Femtosecond phenomena, Laser damage threshold

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Proceedings Article | 17 August 1994 Paper

Temperature dependence of laser-induced breakdown

Daniel Hammer, Rex Eiserer, Gary Noojin, Stephen Boppart, Paul Kennedy, William Roach

Proceedings Volume 2134, (1994) https://doi.org/10.1117/12.182956

KEYWORDS: Laser induced breakdown spectroscopy, Laser induced damage, Laser optics, Picosecond phenomena, Eye, Temperature metrology, Femtosecond phenomena, Visible radiation, Near infrared, Vitreous

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Proceedings Article | 17 August 1994 Paper

Minimum visible retinal lesions from pico- and femtosecond laser pulses

William Roach, Cynthia Toth, Cindy Stein, Gary Noojin, David Stolarski, Clarence Cain

Proceedings Volume 2134, (1994) https://doi.org/10.1117/12.182931

KEYWORDS: Femtosecond phenomena, Picosecond phenomena, Laser damage threshold, Retina, Angiography, Astatine

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Proceedings Article | 7 July 1993 Paper

Shielding effectiveness of femtosecond laser-induced plasmas in ultrapure water

Stephen Boppart, C. Toth, William Roach, Benjamin Rockwell

Proceedings Volume 1882, (1993) https://doi.org/10.1117/12.147675

KEYWORDS: Laser induced breakdown spectroscopy, Plasmas, Pulsed laser operation, Picosecond phenomena, Femtosecond phenomena, Retina, Eye, Laser tissue interaction, Amplifiers, Sensors

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Proceedings Article | 17 June 1993 Paper

Nonlinear transmittance through laser protection barrier: reverse photosaturation of 1-phenylazo 2-napthalenol in polymer host

Michael Mayo, William Roach, Craig Bramlette, M. Gavornik

Proceedings Volume 1864, (1993) https://doi.org/10.1117/12.146892

KEYWORDS: Transmittance, Polymethylmethacrylate, Absorption, Absorbance, Time metrology, Molecules, Polymers, Solid state lasers, Laser damage threshold, Saturable absorption

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Showing 5 of 71 publications

Proceedings Volume Editor (6)

SPIE Conference Volume | 6 March 2009

Optical Interactions with Tissue and Cells XX

SPIE Conference Volume | 25 February 2008

Optical Interactions with Tissue and Cells XIX

SPIE Conference Volume | 6 February 2007

Optical Interactions with Tissue and Cells XVIII

SPIE Conference Volume | 14 February 2006

Optical Interactions with Tissue and Cells XVII

SPIE Conference Volume | 15 April 2005

Optical Interactions with Tissue and Cells XVI

Showing 5 of 6 publications

Conference Committee Involvement (19)

Optical Interactions with Tissue and Cells XXXV

27 January 2024 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXXIV

28 January 2023 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXXIII and Advanced Photonics in Urology

22 January 2022 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXXII

6 March 2021 | Online Only, California, United States

Optical Interactions with Tissue and Cells XXXI

1 February 2020 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXV

3 February 2014 | San Francisco, California, United States

Terahertz and Ultrashort Electromagnetic Pulses for Biomedical Applications

2 February 2014 | San Francisco, California, United States

Terahertz and Ultrashort Electromagnetic Pulses for Biomedical Applications

6 February 2013 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXIV

5 February 2013 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXIII

23 January 2012 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXII

24 January 2011 | San Francisco, California, United States

Optical Interactions with Tissues and Cells XXI

25 January 2010 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XX

26 January 2009 | San Jose, California, United States

Optical Interactions with Tissue and Cells XIX

21 January 2008 | San Jose, California, United States

Optical Interactions with Tissue and Cells XVIII

21 January 2007 | San Jose, California, United States

Optical Interactions with Tissue and Cells XVII

23 January 2006 | San Jose, California, United States

Optical Interactions with Tissue and Cells XVI

24 January 2005 | San Jose, CA, United States

Laser Interaction with Tissue and Cells XV

26 January 2004 | San Jose, CA, United States

Laser Tissue Interaction XIV: Photochemical, Photothermal, Photomechanical

28 January 2003 | San Jose, CA, United States

Showing 5 of 19 Conference Committees

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