Dr. Frits F. M. de Mul Profile

Dr. Frits F. M. de Mul

at Univ of Groningen

SPIE Involvement:

Author

Publications (64)

SPIE Journal Paper | 1 November 2008 Open Access

New laryngoscope for quantitative high-speed imaging of human vocal folds vibration in the horizontal and vertical direction

Nibu George, Frits de Mul, Qingjun Qiu, Gerhard Rakhorst, Harm Schutte

JBO, Vol. 13, Issue 06, 064024, (November 2008) https://doi.org/10.1117/12.10.1117/1.3041164

KEYWORDS: Endoscopes, In vivo imaging, Calibration, Visualization, High speed imaging, Image resolution, Video, 3D image processing, Biomedical optics, Semiconductor lasers

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SPIE Journal Paper | 1 November 2004 Open Access

Photoacoustic mammography laboratory prototype: imaging of breast tissue phantoms

Roy Kolkman, Erwin Hondebrink, Wiendelt Steenbergen, Ton van Leeuwen, Frits de Mul

JBO, Vol. 9, Issue 06, (November 2004) https://doi.org/10.1117/12.10.1117/1.1803548

KEYWORDS: Breast, Photoacoustic spectroscopy, Absorption, Tissue optics, Sensors, Optical spheres, Ultrasonography, Prototyping, Scattering, Mammography

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Proceedings Article | 23 September 2003 Paper

Quasi-parallel laser-Doppler perfusion imaging using a CMOS image sensor

Alexander Serov, W. Steenbergen, F. de Mul, T. Lasser

Proceedings Volume 5067, (2003) https://doi.org/10.1117/12.518488

KEYWORDS: Doppler effect, CMOS sensors, Imaging systems, Sensors, Particles, Blood, Tissues, Charge-coupled devices, CCD image sensors, Photography

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Proceedings Article | 27 August 2003 Paper

Developments in laser Doppler blood perfusion monitoring

Martin Leahy, Frits de Mul, Gert Nilsson, Roman Maniewski, Adam Liebert

Proceedings Volume 4876, (2003) https://doi.org/10.1117/12.475841

KEYWORDS: Doppler effect, Blood, Tissues, Skin, Calibration, Photons, Signal processing, Laser tissue interaction, Semiconductor lasers, Imaging systems

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Proceedings Article | 23 July 2003 Paper

Pulsed laser Doppler flowmetry for increased signal-to-noise ratio and probed depth

Wiendelt Steenbergen, Roy Kolkman, Sven Woldberg, Frits de Mul

Proceedings Volume 4965, (2003) https://doi.org/10.1117/12.478384

KEYWORDS: Doppler effect, Signal to noise ratio, Pulsed laser operation, Tissues, Tissue optics, Signal detection, Scattering, Safety, Semiconductor lasers

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Proceedings Article | 1 July 2003 Paper

Photoacoustic monitoring and imaging of blood vessel size in vivo

Roy Kolkman, John Klaessens, Erwin Hondebrink, Jeroen Hopman, Wiendelt Steenbergen, Ton van Leeuwen, Johan Thijssen, Frits de Mul

Proceedings Volume 4960, (2003) https://doi.org/10.1117/12.477637

KEYWORDS: Photoacoustic spectroscopy, Blood vessels, Sensors, Tissues, In vivo imaging, Blood, Tissue optics, Ear, Image sensors, Veins

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Proceedings Article | 1 July 2003 Paper

Photoacoustic imaging of inhomogeneities embedded in breast tissue phantoms

Srirang Manohar, Alexei Kharine, Johan van Hespen, Wiendelt Steenbergen, Frits de Mul, Ton van Leeuwen

Proceedings Volume 4960, (2003) https://doi.org/10.1117/12.477778

KEYWORDS: Absorption, Breast, Optical spheres, Photoacoustic spectroscopy, Tissue optics, Sensors, Acoustics, Water, Scattering, Ultrasonography

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SPIE Journal Paper | 1 April 2003 Open Access

Temperature modulation of the visible and near infrared absorption and scattering coefficients of human skin

Omar Khalil, Shu-Jen Yeh, Michael Lowery, Xiaomao Wu, Charles Hanna, Stanislaw Kantor, Tzyy-Wen Jeng, Johannes Kanger, Rene Bolt, Frits de Mul

JBO, Vol. 8, Issue 02, (April 2003) https://doi.org/10.1117/12.10.1117/1.1559997

KEYWORDS: Skin, Tissues, Temperature metrology, Modulation, Tissue optics, Blood, Scattering, Reflectivity, Thermal modeling, Lamps

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Proceedings Article | 15 October 2002 Paper

Photoacoustic imaging of blood vessels in tissues

Frits de Mul, Magdalena Pilatou, Roy Kolkman, Erwin Hondebrink, Wiendelt Steenbergen

Proceedings Volume 4903, (2002) https://doi.org/10.1117/12.486606

KEYWORDS: Sensors, Tissues, Blood, Tissue optics, Blood vessels, Photoacoustic spectroscopy, Absorption, Breast, Arteries, Photoacoustic imaging

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Proceedings Article | 16 July 2002 Paper

Probing bulk and near-surface optical properties of phantoms and human skin using a probe with small source-detector distances

Omar Khalil, Johannes Kanger, Xiaomao Wu, Rene Bolt, Shu-Jen Yeh, Frits de Mul

Proceedings Volume 4707, (2002) https://doi.org/10.1117/12.475630

KEYWORDS: Scattering, Skin, Reflectivity, Optical fibers, Optical properties, Tissue optics, Absorption, Tissues, Light, Light scattering

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Proceedings Article | 14 June 2002 Paper

Path length distribution of multiple-scattered photons by low-coherence Doppler interferometry

Anna Petoukhova, Wiendelt Steenbergen, Frits de Mul

Proceedings Volume 4619, (2002) https://doi.org/10.1117/12.470463

KEYWORDS: Doppler effect, Multimode fibers, Mirrors, Photons, Interferometry, Heterodyning, Light scattering, Sensors, Superluminescent diodes, Light sources

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Proceedings Article | 10 June 2002 Paper

Photoacoustic monitoring and imaging of blood vessels in tissue

Roy Kolkman, Magdalena Pilatou, Wiendelt Steenbergen, Frits de Mul

Proceedings Volume 4618, (2002) https://doi.org/10.1117/12.469850

KEYWORDS: Sensors, Blood, Tissues, Tissue optics, Photoacoustic spectroscopy, Blood vessels, Absorption, Breast, Acoustics, Photoacoustic imaging

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Proceedings Article | 13 May 2002 Paper

New generation of integrated probes for laser Doppler perfusion monitoring: construction and in-vivo results

Alexander Serov, Sjoerd Oosterbaan, Janharm Nieland, Herma van Kranenburg, R. Verboom, Herman Bekman, Frits de Mul, Wiendelt Steenbergen

Proceedings Volume 4615, (2002) https://doi.org/10.1117/12.466644

KEYWORDS: Photodetectors, Sensors, Doppler effect, Vertical cavity surface emitting lasers, Semiconductor lasers, Laser beam diagnostics, Digital electronics, Tissue optics, Signal to noise ratio, In vivo imaging

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Proceedings Article | 24 October 2001 Paper

Pulsed laser-Doppler flowmetry for monitoring deep perfusion

Roy Kolkman, Erwin Hondebrink, Rene Bolt, Wiendelt Steenbergen, Frits de Mul

Proceedings Volume 4434, (2001) https://doi.org/10.1117/12.446680

KEYWORDS: Pulsed laser operation, Signal detection, Continuous wave operation, Photons, Blood, Sensors, Kidney, Tissues, Semiconductor lasers

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Proceedings Article | 24 October 2001 Paper

Photoacoustic imaging in phantom materials and in vivo

Magdalena Pilatou, N. Voogd, Frits de Mul, E. Marani, L. van Adrichem

Proceedings Volume 4434, (2001) https://doi.org/10.1117/12.446663

KEYWORDS: Photoacoustic imaging, In vivo imaging, Absorption, Applied physics, Optical imaging, Optical instrument design, Biomedical optics, Tomography, Tissue optics, Light scattering

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Proceedings Article | 23 October 2001 Paper

New developments in non-invasive biomedical optics

Frits de Mul

Proceedings Volume 4606, (2001) https://doi.org/10.1117/12.446708

KEYWORDS: Tissue optics, Light scattering, Blood, Scattering, Tissues, Sensors, Signal detection, Laser scattering, Photoacoustic spectroscopy, Modulation

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Proceedings Article | 22 August 2001 Paper

Dynamic light scattering: a quantitative approach to determination of the fraction of Doppler-shifted photons

Alexander Serov, Wiendelt Steenbergen, Frits de Mul

Proceedings Volume 4427, (2001) https://doi.org/10.1117/12.438415

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Proceedings Article | 15 June 2001 Paper

Photoacoustic imaging of blood perfusion in tissue and phantoms

Magdalena Pilatou, Roy Kolkman, Erwin Hondebrink, Rene Bolt, Frits de Mul

Proceedings Volume 4256, (2001) https://doi.org/10.1117/12.429318

KEYWORDS: Sensors, Tissue optics, Photoacoustic spectroscopy, Tissues, Blood, Bone, Signal processing, Acoustics, Reflection, Photoacoustic imaging

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Proceedings Article | 13 June 2001 Paper

Monitoring of deep structures using a frequency-domain technique: experimental approaches

Andrei Dergatchev, Frits de Mul

Proceedings Volume 4263, (2001) https://doi.org/10.1117/12.429337

KEYWORDS: Signal detection, Modulation, Photons, Scattering, Semiconductor lasers, Optical fibers, Monte Carlo methods, Blood, Phase shifts, Tissue optics

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Proceedings Article | 4 June 2001 Paper

Integrated probes containing a VCSEL and a multidetector chip for laser Doppler tissue perfusion monitoring

Alexander Serov, Sjoerd Oosterbaan, Janharm Nieland, Herma van Kranenburg, Frits de Mul, Wiendelt Steenbergen

Proceedings Volume 4254, (2001) https://doi.org/10.1117/12.427929

KEYWORDS: Doppler effect, Photodetectors, Sensors, Vertical cavity surface emitting lasers, Digital electronics, Semiconductor lasers, Signal to noise ratio, Tissue optics, Light sources, Signal detection

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Proceedings Article | 31 May 2001 Paper

Speckles in laser Doppler blood flowmetry

Alexander Serov, Wiendelt Steenbergen, Frits de Mul

Proceedings Volume 4242, (2001) https://doi.org/10.1117/12.427759

KEYWORDS: Photons, Doppler effect, Speckle, Blood, Ions, Skin, Modulation, Sensors, Photodetectors, Speckle pattern

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Proceedings Article | 22 November 2000 Paper

Radiative transfer through multilayered medium: high-frequency experiments and theory

Andrei Dergatchev, Rene Bolt, Frits de Mul

Proceedings Volume 4163, (2000) https://doi.org/10.1117/12.407647

KEYWORDS: Tissue optics, Scattering, Photons, Radiative transfer, Phase shifts, Tissues, Data modeling, Numerical analysis, Signal detection, Modulation

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Proceedings Article | 31 May 2000 Paper

Scattering properties of human whole blood under simple shear

Wiendelt Steenbergen, Roy Kolkman, Dirk Faber, Frits de Mul

Proceedings Volume 3923, (2000) https://doi.org/10.1117/12.387141

KEYWORDS: Scattering, Blood, Light scattering, Monte Carlo methods, Anisotropy, Glasses, Particles, Multiple scattering, Signal attenuation, Absorption

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Proceedings Article | 31 May 2000 Paper

Application of efficient numerical technique in transport theory for inhomogeneous turbid medium: comparison with experiments

Andrei Dergatchev, Rene Bolt, Frits de Mul

Proceedings Volume 3923, (2000) https://doi.org/10.1117/12.387130

KEYWORDS: Tissue optics, Scattering, Photons, Radiative transfer, Tissues, Data modeling, Numerical simulations, Numerical analysis, Sensors, Optical testing

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Proceedings Article | 19 May 2000 Paper

Photoacoustic a-scanning and monitoring of blood content in tissue

Roy Kolkman, Magdalena Pilatou, Erwin Hondebrink, Frits de Mul

Proceedings Volume 3916, (2000) https://doi.org/10.1117/12.386343

KEYWORDS: Sensors, Blood, Tissue optics, Photoacoustic spectroscopy, Electronics, Tissues, Signal detection, Ferroelectric polymers, Scattering, Absorption

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Proceedings Article | 19 May 2000 Paper

Photoacoustic imaging of microvascular structure in tissue

Magdalena Pilatou, Roy Kolkman, Erwin Hondebrink, Ralph Berendsen, Frits de Mul

Proceedings Volume 3916, (2000) https://doi.org/10.1117/12.386340

KEYWORDS: Sensors, Tissue optics, Signal detection, Electrodes, Detector arrays, Acoustics, Time metrology, Absorption, Blood, Signal to noise ratio

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Proceedings Article | 3 May 2000 Paper

Recent advances in self-mixing laser-Doppler velocimetry: use as an in-vivo blood flow meter

Lorenzo Scalise, Frits de Mul, Wiendelt Steenbergen, Anna Petoukhova

Proceedings Volume 3911, (2000) https://doi.org/10.1117/12.384890

KEYWORDS: Arteries, Semiconductor lasers, Doppler effect, Optical fibers, Sensors, Blood, Blood circulation, In vivo imaging, Velocity measurements, Photodiodes

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Proceedings Article | 28 April 2000 Paper

Low-coherence Doppler interferometry to determine pathlength distribution of multiple-scattered photons

Anna Petoukhova, Wiendelt Steenbergen, Frits de Mul

Proceedings Volume 3915, (2000) https://doi.org/10.1117/12.384148

KEYWORDS: Doppler effect, Photons, Mirrors, Tissue optics, Monte Carlo methods, Interferometry, Blood, Signal detection, Light scattering, Heterodyning

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Proceedings Article | 28 April 2000 Paper

Dynamic speckle patterns formed by a mixture of moving and stationary scatterers: theory and experiment

Alexander Serov, Wiendelt Steenbergen, Frits de Mul

Proceedings Volume 3915, (2000) https://doi.org/10.1117/12.384152

KEYWORDS: Sensors, Doppler effect, Photons, Speckle, Photodetectors, Signal detection, Speckle pattern, Light scattering, Modulation, Skin

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Proceedings Article | 19 April 2000 Paper

Noninvasive determination of concentration of compounds in strongly absorbing biological tissue

Rene Bolt, Johannes Kanger, Frits de Mul, Xiaomao Wu, Shu-Jen Yeh, Omar Khalil

Proceedings Volume 3917, (2000) https://doi.org/10.1117/12.382729

KEYWORDS: Absorption, Scattering, Tissue optics, Monte Carlo methods, Tissues, Reflectivity, Blood, Diffusion, Light scattering, In vivo imaging

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Proceedings Article | 6 April 2000 Paper

Method for estimation of the fraction of Doppler-shifted photons in light scattered by a mixture of moving and stationary scatterers

Alexander Serov, Wiendelt Steenbergen, Frits de Mul

Proceedings Volume 4001, (2000) https://doi.org/10.1117/12.381488

KEYWORDS: Sensors, Doppler effect, Photons, Light scattering, Speckle pattern, Signal detection, Scattering, Speckle, Optical properties, Photodetectors

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Proceedings Article | 15 July 1999 Paper

Photoacoustic tissue scanning (PATS)

Christoph Hoelen, Roy Kolkman, M. Letteboer, Ralph Berendsen, Frits de Mul

Proceedings Volume 3597, (1999) https://doi.org/10.1117/12.356826

KEYWORDS: Sensors, Tissue optics, Photoacoustic spectroscopy, Scattering, Blood, Tissues, Light scattering, Breast, Absorption, Signal detection

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Proceedings Article | 17 May 1999 Paper

Description of an improved laser Doppler calibrator

Wiendelt Steenbergen, Frits de Mul

Proceedings Volume 3599, (1999) https://doi.org/10.1117/12.348364

KEYWORDS: Tissues, Scattering, Tissue optics, Refractive index, Monte Carlo methods, Doppler effect, Calibration, Laser scattering, Particles, Signal processing

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Proceedings Article | 15 January 1999 Paper

Noninvasive detection of glucose using Raman spectroscopy

Johannes Kanger, Frits de Mul, Cees Otto

Proceedings Volume 3570, (1999) https://doi.org/10.1117/12.336922

KEYWORDS: Glucose, Raman spectroscopy, Signal to noise ratio, Luminescence, Spectroscopy, In vivo imaging, Raman scattering, Blood, Light scattering, Error analysis

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Proceedings Article | 15 January 1999 Paper

Angular dependence of light scattering by biological tissue

Rene Bolt, Johannes Kanger, Frits de Mul

Proceedings Volume 3570, (1999) https://doi.org/10.1117/12.336932

KEYWORDS: Scattering, Light scattering, Tissue optics, Monte Carlo methods, Biological research, Tissues, Scatter measurement, Particles, Latex, Collimation

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Proceedings Article | 30 December 1998 Paper

Imaging of cutaneous blood vessels using photoacoustic tissue scanning (PATS)

Christoph Hoelen, Frits de Mul

Proceedings Volume 3566, (1998) https://doi.org/10.1117/12.334361

KEYWORDS: Sensors, Tissue optics, Photoacoustic spectroscopy, Blood vessels, Tissues, Scattering, Blood, Light scattering, Absorption, Acoustics

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Proceedings Article | 19 June 1998 Paper

Role of speckles in laser Doppler flowmetry

Wiendelt Steenbergen, Frits de Mul

Proceedings Volume 3252, (1998) https://doi.org/10.1117/12.311886

KEYWORDS: Photons, Doppler effect, Sensors, Speckle, Laser scattering, Scattering, Tissue optics, Correlation function, Monte Carlo methods, Signal detection

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Proceedings Article | 19 June 1998 Paper

Application of a novel laser Doppler tester including a sustainable tissue phantom

Wiendelt Steenbergen, Frits de Mul

Proceedings Volume 3252, (1998) https://doi.org/10.1117/12.311891

KEYWORDS: Doppler effect, Tissues, Scattering, Tissue optics, Photons, Laser scattering, Laser tissue interaction, Natural surfaces, Absorption, Blood

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SPIE Journal Paper | 1 April 1998 Open Access

Feasibility of picosecond laser-Doppler flowmetry provides basis for time-resolved Doppler tomography of biological tissues

Vladimir Kolinko, Frits de Mul, Jan Greve

JBO, Vol. 3, Issue 02, (April 1998) https://doi.org/10.1117/12.10.1117/1.429887

KEYWORDS: Doppler tomography, Pulsed laser operation, Signal detection, Picosecond phenomena, Tissues, Doppler effect, Laser scattering, Laser sources, Light scattering, Heterodyning

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Proceedings Article | 13 January 1998 Paper

Photoacoustic blood cell detection and imaging of blood vessels in phantom tissue

Christoph Hoelen, Richard Pongers, G. Hamhuis, Frits de Mul, Jan Greve

Proceedings Volume 3196, (1998) https://doi.org/10.1117/12.297931

KEYWORDS: Photoacoustic spectroscopy, Blood, Blood vessels, Tissue optics

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Proceedings Article | 13 January 1998 Paper

New optical tissue phantom and its use for studying laser Doppler blood flowmetry

Wiendelt Steenbergen, Frits de Mul

Proceedings Volume 3196, (1998) https://doi.org/10.1117/12.297935

KEYWORDS: Tissue optics, Doppler effect, Laser tissue interaction, Blood, Optical properties, Polymer thin films, Polymers, Laser development, Monte Carlo methods, Fiber lasers

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Proceedings Article | 2 May 1997 Paper

Coherence effects in laser Doppler blood flowmetry

Wiendelt Steenbergen, Matthijs van Stratum, Frits de Mul, Jan Greve

Proceedings Volume 2982, (1997) https://doi.org/10.1117/12.273602

KEYWORDS: Sensors, Scattering, Doppler effect, Laser scattering, Speckle, Photons, Monte Carlo methods, Light scattering, Anisotropy, Blood

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Proceedings Article | 11 December 1996 Paper

Photoacoustic location of optical absorbers in phantom tissue

Christoph Hoelen, G. Hamhuis, Niko Pagoulatos, Iris van den Ham, Frits de Mul, Jan Greve

Proceedings Volume 2927, (1996) https://doi.org/10.1117/12.260657

KEYWORDS: Tissue optics, Signal detection, Sensors, Photoacoustic spectroscopy, Blood, Optical fibers, Capillaries, Blood vessels, Scattering, Near field optics

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Pulsed photoacoustic (PA) signals may be used for the detection and imaging of blood vessels in tissue. A relatively strong absorption by red blood cells and low absorption by the surrounding tissue, combined with a reasonable penetration depth of the light is found at a wavelength of ca. 577 nm. Experiments were performed with a pulsed frequency doubled Nd:YAG laser which delivered 10 ns pulses at 532 nm wavelength. Ten percent dilutions of India ink and 50% suspensions of red blood cells in PBS were used as optical absorbers. Blood vessels were simulated by hollow nylon fibers with an inner diameter of ca. 250 micrometer through which these suspensions flow. The optical scattering of the surrounding tissue was simulated by a 12% dilution of Intralipid-10% to get a solution with a reduced scattering coefficient of 1.8 mm^-1. The PA signals were detected with a hydrophone that contained four wide band piezoelectric transducers made of 9 micrometer thick PVdF film with an effective diameter of 200 micrometers. Laser pulses with energies up to 8 microjoules were delivered to the sample by a 50 or 100 micrometer core diameter glass fiber. Pulsed optical heating of red blood cells up to 30 - 35 degrees for more than 12,000 times did not affect the photoacoustic response of the cells. If a single fiber is used to illuminate the sample, then even at a depth of 1 mm the PA signals show that the volume that is effectively illuminated is laterally restricted to a diameter of ca. 1 mm. Vessels with blood or ink dilutions were detected up to a depth of more than 1 mm in the scattering medium. Monte- Carlo (MC) simulations were used to simulate the spatial distribution of light absorption in phantom tissue. From this distribution the PA response of blood vessels was simulated. A delay-and-sum beam forming algorithm was developed for 3-D near field configurations and applied to a PA image reconstruction program. The images based on MC simulations as well as experimental data show that the side of larger vessels that is facing the illuminating fiber can be located with a resolution that depends on the configuration and varies between 0.1 and 1 time the inner vessel diameter. This shows the principle and the feasibility of three dimensional photoacoustic dermal tissue imaging.

Proceedings Article | 6 December 1996 Paper

Monte Carlo simulation of transit time dependence of Doppler spectra in dynamic time-resolved tomography

Vladimir Kolinko, Alexander Priezzhev, Frits de Mul

Proceedings Volume 2925, (1996) https://doi.org/10.1117/12.260834

KEYWORDS: Blood, Tissues, Photons, Blood vessels, Monte Carlo methods, Doppler tomography, Tomography, Skin, Doppler effect, Optical simulations

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Proceedings Article | 10 May 1996 Paper

Acceleration of Monte Carlo simulations of laser Doppler blood flowmetry by repeated use of photon trajectories

Vladimir Kolinko, Frits de Mul, Jan Greve, Alexander Priezzhev

Proceedings Volume 2678, (1996) https://doi.org/10.1117/12.239526

KEYWORDS: Doppler effect, Monte Carlo methods, Particles, Light scattering, Scattering, Computer simulations, Photodetectors, Error analysis, Tissues, Blood

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Proceedings Article | 10 May 1996 Paper

Signal optimization in glass-fiber self-mixing intra-arterial laser Doppler velocimetry

Frits de Mul, M. van Herwijnen, P. Moes, Jan Greve

Proceedings Volume 2678, (1996) https://doi.org/10.1117/12.239524

KEYWORDS: Doppler effect, Modulation, Glasses, Mirrors, Semiconductor lasers, Light scattering, Velocity measurements, Fiber lasers, Particles, Laser resonators

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Proceedings Article | 9 February 1996 Paper

Coherence effects in modeling laser-Doppler perfusion flowmetry

Frits de Mul, Wiendelt Steenbergen, T. Vonck, Jan Greve

Proceedings Volume 2732, (1996) https://doi.org/10.1117/12.231681

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Proceedings Article | 15 January 1996 Paper

Nondestructive photoacoustic subsurface tissue imaging: a feasibility study

Christoph Hoelen, Frits de Mul, Jan Greve

Proceedings Volume 2628, (1996) https://doi.org/10.1117/12.230000

KEYWORDS: Signal detection, Sensors, Spherical lenses, Acoustics, Light scattering, Tissue optics, Signal generators, Scattering, Tissues, Ferroelectric polymers

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Proceedings Article | 15 January 1996 Paper

Phase delays in reflectance pulse oximetry: a Monte Carlo study

Reindert Graaff, A. Dassel, W. Zijlstra, Frits de Mul, Jan Aarnoudse

Proceedings Volume 2628, (1996) https://doi.org/10.1117/12.230004

KEYWORDS: Sensors, Scattering, Monte Carlo methods, Absorption, Blood, Oximetry, Infrared radiation, Reflectivity, Light scattering, Oxygen

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Proceedings Article | 8 January 1996 Paper

Noise suppression and correction of laser Doppler blood flow spectra after high-pass filtering

K. Wierda, Reindert Graaff, R. van Someren, Frits de Mul, B. Leerkotte, Jan Greve

Proceedings Volume 2629, (1996) https://doi.org/10.1117/12.229525

KEYWORDS: Doppler effect, Sensors, Digital signal processing, Blood circulation, Signal processing, Signal detection, Interference (communication), Filtering (signal processing), Optical filters, Skin

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Proceedings Article | 27 December 1995 Paper

Tissue-optical model to determine changes in saturation and blood volume during ischemia

A. Talsma, Reindert Graaff, Frits de Mul, W. Ament, Jan Greve

Proceedings Volume 2627, (1995) https://doi.org/10.1117/12.228897

KEYWORDS: Blood, Sensors, Tissues, Scattering, Tissue optics, Absorption, Skin, Ischemia, Light emitting diodes, Diffusion

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Proceedings Article | 18 December 1995 Paper

Coherence effects in modeling laser-Doppler perfusion flowmetry

Frits de Mul, Wiendelt Steenbergen, T. Vonck, Jan Greve

Proceedings Volume 2626, (1995) https://doi.org/10.1117/12.228677

KEYWORDS: Photons, Doppler effect, Homodyne detection, Heterodyning, Scattering, Sensors, Monte Carlo methods, Particles, Light scattering, Signal detection

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Proceedings Article | 31 January 1995 Paper

Measurements and simulations of dynamic light scattering in an upscaled tissue blood flow model

Frits de Mul, Jan Greve, Marco Koelink, Reindert Graaff, Jan Aarnoudse

Proceedings Volume 2326, (1995) https://doi.org/10.1117/12.200828

KEYWORDS: Doppler effect, Scattering, Photons, Monte Carlo methods, Homodyne detection, Sensors, Heterodyning, Laser scattering, Absorption, Tissues

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Proceedings Article | 14 September 1993 Paper

Photon migration in upscaled tissue models: measurements and Monte Carlo simulations

Frits de Mul, Marco Koelink, M. Kok, Jan Greve, Reindert Graaff, A. Dassel, Jan Aarnoudse

Proceedings Volume 1888, (1993) https://doi.org/10.1117/12.154629

KEYWORDS: Doppler effect, Monte Carlo methods, Sensors, Tissue optics, Scattering, Absorption, Particles, Liquids, Light scattering, Skin

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Proceedings Article | 14 September 1993 Paper

Condensed Monte Carlo simulations applied to reflectance pulse oximetry

Reindert Graaff, A. Dassel, Marco Koelink, Jan Aarnoudse, Frits de Mul, W. Zijlstra, Jan Greve

Proceedings Volume 1888, (1993) https://doi.org/10.1117/12.154637

KEYWORDS: Monte Carlo methods, Sensors, Oximetry, Absorption, Blood, Reflectivity, Scattering, Light emitting diodes, Optical properties, Infrared radiation

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Proceedings Article | 6 August 1993 Paper

Glass fiber self-mixing laser Doppler velocimetry: technical aspects and biomedical applications

Frits de Mul, Marco Koelink, Jan Greve, Reindert Graaff, A. Dassel, Jan Aarnoudse

Proceedings Volume 2052, (1993) https://doi.org/10.1117/12.150501

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Proceedings Article | 21 May 1993 Paper

Blood velocity measurements using a fiber-coupled self-mixing diode-laser Doppler velocimeter

Frits de Mul, Marco Koelink, Ralph Berendsen, Jan Greve, Reindert Graaff, A. Dassel, Jan Aarnoudse

Proceedings Volume 1886, (1993) https://doi.org/10.1117/12.144835

KEYWORDS: Blood, Doppler effect, Velocity measurements, Fiber lasers, Arteries, Glasses, Blood circulation, Fiber optics sensors, Medical diagnostics, Semiconductor lasers

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SPIE Journal Paper | 1 February 1993

Reindert Graaff, Jan Aarnoudse, Frits de Mul, Henk Jentink

OE, Vol. 32, Issue 02, (February 1993) https://doi.org/10.1117/12.10.1117/12.60735

KEYWORDS: Scattering, Rayleigh scattering, Diffusion, Monte Carlo methods, Light scattering, Absorption, Signal attenuation, Interfaces, Tissues, Blood

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Proceedings Article | 1 August 1991 Paper

In-vivo blood flow velocity measurements using the self-mixing effect in a fiber-coupled semiconductor laser

Marco Koelink, M. Slot, Frits de Mul, Jan Greve, Reindert Graaff, A. Dassel, Jan Aarnoudse

Proceedings Volume 1511, (1991) https://doi.org/10.1117/12.45984

KEYWORDS: Blood, Blood circulation, Doppler effect, Semiconductor lasers, In vivo imaging, Modulation, Velocity measurements, Fiber lasers, In vitro testing, Fiber optics sensors

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